Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,632

Sort By: Relevance

$95K - $115K *

Unlock your potential in a dynamic role focused on strategic account development and clinical support within the medical device sector, driving growth and collaboration across healthcare systems in th...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $160K *

Lead the charge in driving strategic sales growth within higher education, transforming complex challenges into solutions. Collaborate cross-functionally to enhance market share and establish lasting...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$149K - $198K *

Champion the investigation and diagnosis of complex AV behaviors, driving solutions autonomously across simulation and on-road environments. Utilize Python and custom tools to enhance diagnostic capab...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Transportation

$100K - $104K *

Manage daily property operations, lead a dedicated team, and drive leasing success while ensuring resident satisfaction and financial performance in a dynamic environment...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Real Estate & Construction

$175K - $210K *

Drive your career forward by leading strategic partnerships in precision medicine. This role focuses on executive relationships, enterprise account strategies, and cross-functional collaboration to en...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Champion innovative software solutions by leveraging your expertise in Java Spring Boot and Angular. Collaborate with teams to enhance applications, streamline processes, and ensure optimal performanc...

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$180K - $220K *

Manage strategic partnerships with C-suite executives in healthcare, driving enterprise adoption of precision medicine solutions. Collaborate across teams to implement and scale initiatives, ensuring...

North Carolina, USRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$106K - $167K *

Elevate your career by optimizing ERP systems, crafting integration solutions, and enhancing performance for business success. Collaborate with cross-functional teams to deliver high-quality projects...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Information Technology

$75K - $90K *

Lead impactful proposal and communication strategies, partnering with sales teams to deliver compelling RFP responses, optimize materials, and support business pursuits for effective client engagement...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Transportation

$125K - $168K *

Pioneer application modernization efforts by leading agile teams, driving technical outcomes, and enhancing developer experiences. Collaborate with clients to deliver measurable business results while...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Join a team that's redefining mechanical contracting by leading a dynamic branch. Oversee construction and service operations, manage P&L, and drive business growth while guiding a talented team of ov...

Yesterday

  •   8 - 10 years exp.  •   Staffing

$160K - $200K *

Drive growth by leading strategic partnerships in healthcare tech. Collaborate with executives to shape joint strategies, negotiate impactful deals, and operationalize go-to-market initiatives that en...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$190K - $249K *

Join a team that's bridging technical solutions with client needs, driving digital transformation. Leverage your expertise to build relationships, influence decisions, and ensure customer success thro...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Transform demand generation strategies in the Consumer & Life Sciences sectors. Lead initiatives to create impactful marketing campaigns, enhance customer engagement, and collaborate with cross-functi...

Reposted yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$77K - $144K *

Oversee the onboarding program and training processes, ensuring compliance and efficiency. Collaborate with stakeholders to enhance LMS functionality and support continuous improvement initiatives whi...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Champion patient recovery by delivering individualized, evidence-based physical therapy. Collaborate with a dedicated team to enhance mobility and improve lives, while fostering professional growth an...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$98K - $115K *

Join a team that's dedicated to delivering innovative payment solutions while leading audit engagements. As an Audit Project Manager, you'll supervise staff, ensure quality work, and collaborate acros...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$142K - $202K *

Unlock commercial potential by executing transformation workstreams, collaborating with cross-functional teams, and delivering strategic insights to drive measurable results in a healthcare-focused en...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Elevate AI experiences from concept to value by collaborating with engineering and design teams. Drive strategy, build prototypes, and make data-driven decisions to enhance user engagement and product...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Help us shape the future of federal security architecture by developing integrated designs and compliance strategies that protect sensitive information while ensuring reliable business operations acro...

Yesterday

  •   8 - 10 years exp.  •   Real Estate & Construction

$160K - $200K *

Transform client relationships by driving business growth, securing profitable projects, and leveraging market access expertise. Lead teams to exceed expectations while identifying industry trends and...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$165K - $220K *

Join a team that's redefining avionics systems engineering by translating customer needs into innovative architectures and requirements. Collaborate across domains to deliver high-quality solutions in...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Aerospace & Defense

$66K - $105K *

Join a team that's dedicated to delivering exceptional patient care through comprehensive assessments, individualized care plans, and effective collaboration with healthcare professionals to enhance p...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Drive your career with a strategic sales leadership role focused on enterprise growth in healthcare. Lead complex business development efforts, build executive relationships, and shape solutions that...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$130K - $155K *

Lead the AI/ML product strategy across multiple business units, driving integration and data-centric solutions that enhance customer value and revenue growth through innovative workflows and collabora...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.