Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,788

Sort By: Relevance

$76K - $114K *

Drive innovative fire sprinkler designs by preparing detailed CAD drawings, performing hydraulic calculations, and collaborating with installation teams to ensure code compliance and optimal system pe...

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$76K - $114K *

Design innovative fire sprinkler systems by preparing detailed CAD drawings, performing hydraulic calculations, and collaborating with installation teams to ensure code compliance and effective execut...

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$90K - $95K *

Transform engagement in legal education by managing relationships, driving program success, and supporting bar exam strategies across multiple states. Collaborate with schools and students to enhance...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Develop scalable applications and enhance cloud-based solutions in a dynamic team. Leverage your Python expertise to tackle complex challenges and contribute to enterprise financial technology initiat...

Today

  •   8 - 10 years exp.  •   Staffing

$89K - $105K *

Deliver compelling marketing and policy content that enhances brand voice and reputation. Collaborate with teams to translate complex topics into clear narratives, ensuring high-quality, timely materi...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Collaborate with cross-functional teams to design and maintain scalable security data pipelines, ensuring accurate telemetry ingestion and compliance with governance standards for enhanced cybersecuri...

Charlotte, NCRemote

Today

  •   Less than 5 years exp.  •   Staffing

$150K - $180K *

Unlock potential by managing strategic accounts, driving revenue growth, and fostering executive relationships. Lead a sales team to enhance B2B display solutions while collaborating cross-functionall...

RemoteRemote

Today

  •   11 - 15 years exp.  •   Consumer Technology

$80K - $95K *

Champion the future of program financial analysis by overseeing Earned Value Management Systems, ensuring compliance and performance tracking while providing strategic financial support and insights t...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Technical Services

$110K - $130K *

Join a team that's redefining digital experiences by leading complex design initiatives, mentoring designers, and enhancing user journeys across patient and employee platforms while collaborating clos...

Today

  •   8 - 10 years exp.  •   Healthcare

$94K - $266K *

Drive impactful healthcare technology programs by leading cross-functional teams, ensuring high-quality delivery, and fostering strong client relationships to achieve measurable business outcomes and...

Today

  •   5 - 7 years exp.  •   Business Services

$160K - $190K *

Champion a national team of Medical Science Liaisons focused on obesity, driving strategy and KOL engagement. Lead cross-functional collaboration and ensure compliance while developing high-performing...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Drive your career forward by leading client engagement and market development in Knowledge & Research Services. Build relationships, shape client needs, and oversee impactful programs while collaborat...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$132K - $251K *

Drive the transformation of business processes and systems by leveraging your expertise in ERP solutions, particularly SAP S/4HANA, to enhance Order to Cash operations and ensure successful project de...

Today

  •   8 - 10 years exp.  •   Aerospace & Defense

$194K - $230K *

Transform healthcare delivery by leading complex technology programs. Collaborate with cross-functional teams to ensure high-quality, on-time results while enhancing client relationships and driving m...

Today

  •   5 - 7 years exp.  •   Business Services

$135K - $150K *

Unlock potential by leading full-cycle accounting operations, managing distributed teams, and driving process excellence. Collaborate with leadership to ensure compliance and enhance financial reporti...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $105K *

Grow your career with a dynamic role in healthcare sales, focusing on building relationships within the dermatology community. Drive product usage and meet volume goals while traveling extensively wit...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Shape enterprise-scale data architectures that empower trusted, governed data. Collaborate with engineering teams to design scalable solutions, optimize performance, and lead innovative data initiativ...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$75K - $90K *

Lead the strategic expansion of assessment measures and platform capabilities. Own the product roadmap, collaborate with cross-functional teams, and enhance educator tools to improve student support a...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Explore opportunities to enhance liquidity strategies through data analysis, regulatory reporting, and process improvement. Collaborate across teams to drive optimal bank-wide liquidity management and...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$125K - $145K *

Lead the charge in building and delivering data products that empower leadership and client engagements. This hands-on role requires strategic oversight and collaboration to ensure high-quality analyt...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$91K - $104K *

Lead the development and implementation of innovative therapy programs, ensuring high-quality patient care and compliance with standards in a dynamic senior living environment. Supervise a team of the...

Today

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Manage security operations by analyzing threats, responding to incidents, and developing response plans. Collaborate with teams to enhance detection efforts and maintain compliance while utilizing adv...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Business Services

$106K - $122K *

Advance global immunization efforts by managing strategic partnerships and implementing evidence-based solutions to enhance vaccine demand and delivery in low and middle-income countries, focusing on...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform the future of application development by leading complex projects, coding, and enhancing software solutions. Collaborate with teams to design, troubleshoot, and optimize applications while m...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$163K - $297K *

Champion the development and execution of innovative digital product strategies across EMEA, enhancing consumer experiences and driving key performance indicators in a high-growth e-commerce environme...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.