Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and technology roles to positions in finance, healthcare, engineering, and operations. Whether you’re considering a move to a major city or looking for opportunities closer to home, explore roles that match your experience and career goals.

Where to Find High-Paying Jobs in Ohio

Ohio’s job market spans major metropolitan areas and growing regional economies. Explore opportunities in Columbus, Cleveland, Cincinnati, and other communities throughout the state. Employers across industries seek experienced professionals for roles in corporate leadership, technology, healthcare, manufacturing, financial services, and more. Available positions and compensation vary by employer, location, and qualifications.

Industries and Career Paths

Ohio offers career possibilities across established and emerging sectors. Depending on your background, you may find senior-level opportunities in business management, software and information technology, healthcare administration, engineering, supply chain, sales, and finance. Use Ladders to search current listings and identify roles suited to your skills and professional experience.

Find the Right Ohio Opportunity

Make your search more focused by filtering listings by location, job title, industry, and other preferences. Review each posting for its responsibilities, requirements, and compensation details, then tailor your application to highlight relevant accomplishments. New opportunities are added over time, so check back regularly for the latest $100K+ jobs in Ohio.

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$130K - $145K *

Lead the charge in driving client success and commercial growth by managing strategic relationships, identifying upsell opportunities, and ensuring client satisfaction across a diverse portfolio in th...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $125K *

Advance your career by coordinating healthcare technology integration across multiple VA sites. Leverage your project management skills to support the Federal Electronic Health Record Modernization pr...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$136K - $184K *

Bring your expertise to design a data pipeline architecture that transforms complex healthcare data into automated fraud alerts, while maintaining compliance and driving innovation throughout the proj...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$134K - $241K *

Drive compliance and excellence by overseeing high-value contract management operations, ensuring conformity to policies while supporting complex negotiations with federal and commercial stakeholders...

US-AnywhereRemote

4 weeks ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$88K - $154K *

Lead the charge in high-quality process design for complex industrial projects, collaborating across disciplines to ensure effective delivery from concept to detail, while driving execution in a dynam...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$103K - $181K *

Join a dynamic team to automate and enhance software delivery for critical systems. Collaborate with cross-functional teams to ensure system reliability and performance while supporting national secur...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$145K - $170K *

Support our dynamic IT team by architecting and leading enterprise storage solutions. Drive innovations in hybrid cloud infrastructures while mentoring fellow professionals and ensuring optimal servic...

US-AnywhereRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$90K - $110K *

Lead the charge in executing critical construction projects, directing field teams and managing multifaceted operations from kickoff to completion, ensuring quality and safety while fostering stakehol...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$85K - $95K *

Unlock potential by providing clinical and technical expertise to surgeons in the operating room, ensuring effective use of advanced navigation technologies while cultivating strong customer relations...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $180K *

Shape innovative solutions by leading customer discovery and technical workshops. Collaborate with cross-functional teams to define infrastructure needs and deliver compelling proposals that drive bus...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Elevate your career by leading mission-critical data center operations, ensuring infrastructure reliability, and driving performance excellence. Take ownership of governance, risk management, and cust...

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$205K - $285K *

Lead a high-performing technical team to ensure top-tier installation, configuration, and maintenance of server hardware and software, driving operational excellence and optimizing processes in a dyna...

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $190K *

Grow your career with a leadership role in cybersecurity, driving strategy and operations across AI-driven platforms. Lead a team to enhance security architecture, manage incident response, and collab...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $110K *

Join our team to deliver innovative waste management solutions. Collaborate with clients to optimize operations through tailored technology integrations and enhance sustainability efforts while drivin...

US-AnywhereRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Transportation

$242K - $363K *

Lead the charge in defining and evolving a global ERP platform strategy, maximizing value through end-to-end transformation of core business processes while ensuring compliance and high performance in...

US-AnywhereRemote

3 days ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$250K - $290K *

Join a team that's redefining data platforms, leading architecture and engineering efforts while shaping and scaling a reliable, next-generation data warehouse for analytics and machine learning capab...

US-AnywhereRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$255K - $290K *

Drive the technical vision for a complex database platform, ensuring scalability and performance. Lead architecture decisions, mentor engineers, and collaborate across teams to enhance data infrastruc...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $190K *

Lead and innovate in cybersecurity by enhancing security delivery through automation and AI. Collaborate across teams to identify gaps, improve compliance, and strengthen processes, ensuring consisten...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$125K - $150K *

Champion security excellence by driving secure SDLC practices, managing compliance, and leading incident response. Collaborate with DevOps and ensure robust risk management practices to protect vital...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$145K - $175K *

Elevate enterprise architecture by driving digital transformation and cloud modernization. Collaborate with leadership to align technology strategies with business goals, focusing on AI, RPA, and inno...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $155K *

Join us to drive digital transformation and enterprise architecture across multiple units, focusing on cloud modernization, AI, and RPA. Collaborate with leadership to align technology solutions with...

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $200K *

Drive account growth by managing client relationships and fostering strategic partnerships. This dynamic role engages with clients, executing sales strategies to expand product adoption while ensuring...

US-AnywhereRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$103K - $193K *

Take ownership of account relationships across hyperscale and 5G sectors while driving sales strategies in a dynamic, collaborative environment. Leverage your technical expertise to advance opportunit...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$110K - $130K *

Lead the design and optimization of mechanical systems for data centers, ensuring reliability, energy efficiency, and compliance. Collaborate with cross-functional teams to enhance operational perform...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$130K - $155K *

Optimize and implement scalable, secure infrastructure solutions across Windows, Citrix, AWS, and Azure. Drive automation and collaborate with teams to design zero-trust architectures, enhancing infra...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Listings may include professional and senior-level roles in fields such as technology, healthcare, finance, engineering, manufacturing, sales, and business operations. Job availability depends on current employer postings.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Explore listings in Columbus, Cleveland, Cincinnati, and other Ohio cities and communities. Use location filters to find opportunities in the areas that work for you.

  • How can I search for jobs in Ohio on Ladders?question toggle

    Browse Ohio job listings and narrow your results by location, job title, industry, or other available filters. Check each posting for salary information, qualifications, and application instructions.

  • Are Ohio jobs on Ladders guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, since pay and eligibility requirements vary by role and employer.