Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $116,335
Industry Director - Digital Plant Sales
$150K - $180K *
Lead the charge in driving sales growth and market leadership for Digital Plant solutions. Collaborate with teams to develop strategies, manage key accounts, and ensure high-quality project delivery w...
1 week ago
Project Manager II - Digital Plant
$90K - $110K *
Transform digital plant projects through effective management, ensuring successful delivery while overseeing scope, budget, and client satisfaction. Collaborate with teams to drive project success and...
1 week ago
Project Manager III - Energy/Solar
$95K - $115K *
Lead the successful delivery of automation projects by managing scope, budget, and client expectations. Collaborate with teams to ensure project profitability and client satisfaction while maintaining...
1 week ago
$150K - $180K *
Join a team that's redefining customer success by leveraging AI to enhance the post-sale journey. Lead and scale a dynamic team while driving retention and expansion for enterprise clients in a fast-p...
1 week ago
Senior Program Manager, People Data Access & Governance
$123K - $207K *
Champion the design and ownership of a robust People Data Access & Governance framework, ensuring responsible data access while partnering with cross-functional teams to navigate compliance and ethica...
Reposted 1 week ago
Project Lead, Client Onboarding (Remote)
$88K - $105K *
Manage the end-to-end onboarding of healthcare clients, leading cross-functional teams to ensure smooth transitions into coding and billing services while driving operational improvements and maintain...
1 week ago
Senior Project Manager, Isotopes
$120K - $195K *
Drive the development and execution of strategic projects for radioisotope production facilities. You will lead cross-functional teams to ensure operational readiness, regulatory compliance, and succe...
Reposted 1 week ago
$110K - $130K *
Partner with us to design and implement cloud-native data solutions, ensuring secure and reliable data exchange across platforms. Collaborate with teams to enhance data accessibility and support advan...
1 week ago
$80K - $95K *
Join a team that's dedicated to advanced support for industrial control systems. As a key escalation point, you'll tackle complex issues, drive system stability, and mentor junior staff in a dynamic 2...
1 week ago
$240K - $300K *
Empower strategic partnerships across the Eastern U.S. to drive revenue growth. Build and manage a partner-sourced pipeline, enhance customer engagement, and accelerate deal closures through collabora...
1 week ago
SR DISTRIBUTOR SALES MANAGER - NORTHERN COASTAL CALIFORNIA
$98K - $153K *
Grow your career with a leadership role focused on wholesaler management, driving sales and market share through team development and strategic planning. Collaborate with national accounts to achieve...
1 week ago
Sr. Data Scientist - Measurement
$160K - $195K *
Innovate with us to develop and deploy cutting-edge AI solutions that enhance advertising measurement products. Collaborate across teams to drive impactful data-driven decisions and expand our capabil...
1 week ago
$83K - $87K *
Elevate your career by ensuring the reliability of industrial electrical systems. Utilize your expertise to troubleshoot, maintain, and enhance electrical infrastructure while adhering to safety stand...
1 week ago
$125K - $150K *
Lead the charge in driving trailer sales and leasing operations, overseeing team performance, managing P&L, and cultivating customer relationships to achieve strategic growth and operational excellenc...
1 week ago
$120K - $145K *
Empower your career by leading data architecture initiatives across Oracle Cloud applications. Drive data governance, migration, and integration strategies to enhance business processes and ensure dat...
1 week ago
North America Head of Brands Innovation
$150K - $180K *
Drive brand engagement and innovation through strategic partnerships, workshops, and marketing campaigns, leveraging HP digital print technology to inspire growth and creativity in collaboration with...
1 week ago
Regional Sales Director - Nashville
$180K - $215K *
Transform your career by leading regional sales efforts, driving product launch success, and building high-performing teams. Collaborate cross-functionally to achieve sales goals and foster strong cus...
1 week ago
Regional Sales Director - Long Island
$180K - $215K *
Inspire growth by leading regional launch strategies and building high-performing sales teams. Drive market success through strong customer relationships and cross-functional collaboration in a fast-p...
1 week ago
$95K - $115K *
Transform project delivery by leading multidisciplinary design coordination for complex industrial projects, ensuring seamless integration between clients, engineering teams, and external partners thr...
1 week ago
Project Engineer, Electrical Procurement
$80K - $95K *
Unlock your potential by managing sourcing and procurement for electrical projects. Collaborate with teams to ensure timely delivery of materials while mitigating risks and maintaining quality standar...
1 week ago
Manager, Growth & Customer Marketing
$155K - $185K *
Champion growth and customer marketing by leading a dynamic team to drive full-funnel strategies, optimize campaigns, and leverage AI tools for enhanced performance and insights. Shape the future of m...
1 week ago
$200K - $225K *
Elevate customer operations by leading Loan Fulfillment, Customer Experience, and Collections teams. Drive efficiency, enhance applicant experiences, and manage vendor relationships to ensure a seamle...
1 week ago
Physician/Deputy ACOS Primary Care Service
$180K - $220K *
Join a team that's dedicated to enhancing primary care for Veterans. Lead clinical initiatives, supervise staff, and engage in quality improvement projects while providing comprehensive patient care i...
1 week ago
$145K - $165K *
Drive your career by owning the end-to-end data platform, designing and maintaining scalable pipelines and infrastructure. Collaborate with analytics teams to ensure data quality and governance while...
1 week ago
$98K - $172K *
Inspire patient care excellence by providing pharmaceutical services, counseling, and immunizations. Engage with the community and ensure compliance while leading pharmacy staff in delivering top-notc...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.