Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $116,335
$120K - $145K *
Join a team that's redefining product management by leading cross-product initiatives and shared services. Collaborate with diverse teams to drive innovation, enhance platform capabilities, and delive...
1 week ago
Senior Growth Marketing Manager - Business & Government
$105K - $150K *
Champion integrated marketing campaigns that drive pipeline growth in the Business & Government sector. Collaborate across teams to execute strategies, optimize performance, and leverage AI for innova...
1 week ago
$90K *
Lead the charge in driving field marketing initiatives that convert events and partnerships into qualified sales opportunities, collaborating closely with sales teams to optimize pipeline contribution...
1 week ago
$120K - $140K *
Join a team that's driving sales success by engaging clients, managing opportunities, and closing deals. Leverage your expertise to present solutions and collaborate with internal teams to achieve rev...
1 week ago
Operations Excellence Lead, Pet Insurance - REMOTE
$87K - $162K *
Engage in transformative process improvement initiatives, collaborating with leaders to analyze and redesign workflows. Drive efficiency and quality across multiple business units, creating lasting va...
1 week ago
$110K - $130K *
Drive strategic program management by coordinating activities, ensuring stakeholder alignment, and overseeing complex deliverables to enhance overall business performance and effectiveness across func...
1 week ago
$158K - $213K *
Oversee day-to-day accounting and treasury operations, ensuring accuracy and compliance. Lead month-end close processes, refine internal controls, and develop a high-performing team while integrating...
Reposted 1 week ago
$203K - $319K *
Lead and optimize commercial operations to drive growth, enhance revenue strategies, and streamline processes. Collaborate with cross-functional teams to ensure effective execution of sales initiative...
1 week ago
$102K - $231K *
Empower innovation by delivering key technical features and mentoring teams. Collaborate across departments to enhance software quality and performance while driving the architectural direction of log...
1 week ago
Senior Group Product Manager, Marketing Platform
$187K - $260K *
Lead the charge in shaping our marketing technology ecosystem, driving product strategy and team development while enhancing workflows and cross-channel capabilities for data-driven marketing success...
1 week ago
Physician - Family Medicine Physician Opportunity in Winghaven MO
$210K - $250K *
Make your mark at a leading primary care practice, providing exceptional outpatient care while enjoying a supportive environment, work-life balance, and collaboration with advanced providers to enhanc...
1 week ago
$80K - $95K *
Empower scientific innovation by providing expert installation and maintenance of advanced analytical equipment. Build strong customer relationships while resolving complex issues and ensuring optimal...
1 week ago
Senior Consultant, Healthcare Finance (Healthcare & Medicaid Finance and Analysis)
$95K - $130K *
Unlock potential by driving healthcare finance consulting excellence. Collaborate with project teams to enhance service delivery through financial modeling, data analytics, and quality improvement ini...
1 week ago
$90K - $100K *
Join a team that's dedicated to ensuring sales compensation accuracy and integrity. You'll support deal desk operations and provide analytical insights, making a significant impact on revenue processe...
1 week ago
Staff/Principal Design Systems Lead
$150K - $180K *
Drive the evolution of our design system by building foundational infrastructure that empowers designers, engineers, and AI agents to create cohesive, high-quality experiences while leading a growing...
1 week ago
Micro-Architect and RTL Designer
$160K - $500K+*
Drive innovative silicon design methodologies, overseeing subsystem and chip-level deliverables from micro-architecture to sign-off. Collaborate with cross-functional teams to achieve optimal performa...
1 week ago
Organic Growth Manager, SEO & AEO
$108K - $123K *
Shape the future of our SEO and AEO strategy by driving organic growth through innovative content mapping and AI-informed tactics. Collaborate across teams to enhance discoverability and ensure measur...
1 week ago
Managing Director, Investor Advisory
$160K - $200K *
Lead the translation of investment strategies into tailored client policies, ensuring alignment with firm philosophy. Drive portfolio reviews, client communication, and advisor training while collabor...
1 week ago
General Manager, Central (Delivery Station Regional Leader)
$175K - $195K *
Elevate operations by leading multi-site logistics and final-mile delivery. Drive efficiency, safety, and customer satisfaction while managing budgets and developing talent across the Central region...
1 week ago
GTM Enablement Program Manager - AI Content Infrastructure
$136K - $185K *
Accelerate progress at our enterprise AI chatbot platform by developing dynamic GTM content strategies, architecting AI workflows, and optimizing enablement materials to enhance sales effectiveness an...
1 week ago
Digital Delivery Manager - Energy Advisory | 1898 & Co
$110K - $130K *
Advance your career by leading digital delivery and innovation in Energy Advisory. Collaborate across teams to connect business needs with digital solutions, ensuring scalable and sustainable project...
1 week ago
Water Resources Engineer in Training
$75K - $100K *
Advance your career by supporting our Water Resources design team on diverse projects, including drainage, potable water, and wastewater infrastructure. Collaborate with experienced engineers in a dyn...
1 week ago
$108K - $130K *
Champion the design and evolution of data platforms, ensuring scalable ingestion and governed consumption. Collaborate with stakeholders to translate requirements into robust solutions while providing...
1 week ago
$69K - $101K *
Unlock potential by delivering comprehensive clinical care management services, enhancing health outcomes for diverse populations through assessment, care planning, and coordination across multiple he...
1 week ago
Oracle Fusion PPM - Project Accounting SME
$125K - $150K *
Champion project accounting excellence by leading Oracle Fusion PPM migrations. Collaborate with cross-functional teams to drive successful implementations and optimize processes, ensuring alignment w...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.