Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$110K - $130K *
Engage with enterprise clients to drive sales growth through strategic prospecting, relationship building, and consultative solutions. Collaborate with brokers and leverage marketing strategies to exc...
1 week ago
Manager, Sales Engineering - SMB
$154K - $221K *
Lead the charge in shaping the sales engineering team for core solutions, driving revenue growth through strategic partnerships and innovative problem-solving in a dynamic environment...
1 week ago
Senior Product Owner (HYBRID - LOCAL CANDIDATES ONLY, DALLAS TX)
$110K - $130K *
Unlock potential by leading Agile delivery teams and managing product backlogs. Collaborate with stakeholders to translate business needs into actionable user stories, ensuring alignment with strategi...
1 week ago
Personnel Security Division Director
$110K - $130K *
Lead personnel security programs by directing operations, overseeing adjudications, and managing staff to ensure compliance with federal standards while enhancing the integrity of the Federal workforc...
1 week ago
Practice Manager - Fertility & Reproductive Medicine
$70K - $109K *
Champion divisional operations by ensuring adherence to policies, overseeing staff, and enhancing patient services. Collaborate on strategic planning and financial oversight to drive efficiency and qu...
1 week ago
Market Development Manager - Remote (Burbank or Pasadena)
$80K - $95K *
Transform sales performance by collaborating with distributors to enhance market presence and drive growth in the assigned territory. Leverage your expertise in DSD sales to develop local chains and e...
1 week ago
Regional Sales Manager - Remote (Boston)
$95K - $115K *
Unlock potential by leading a distributor network to drive sales growth, ensuring effective execution of business plans and fostering strong relationships within the marketplace. This role requires st...
1 week ago
Staff Software Engineer- AI Platform
$150K - $180K *
Develop and manage scalable AI infrastructure solutions, ensuring secure access to foundation models. Collaborate with cross-functional teams to enhance platform capabilities and drive AI adoption whi...
1 week ago
Senior Executive Talent Partner
$111K - $207K *
Empower growth by shaping executive talent strategies that drive success. Partner with senior leaders to enhance recruitment processes, develop talent pipelines, and advise on market trends, while ens...
Reposted 1 week ago
Configuration Management Specialist
$85K - $90K *
Elevate the future of U.S. Coast Guard acquisitions by managing configuration processes for the Waterways Commerce Cutter. Collaborate with teams to ensure compliance and accuracy in documentation and...
1 week ago
Principal Consultant - Utility Revenue Requirements Specialist
$128K - $191K *
Elevate your career by managing utility revenue requirements projects, preparing regulatory filings, and providing expert testimony. Collaborate with clients across North America while leading teams a...
1 week ago
$95K - $115K *
Champion IT audit initiatives by leading comprehensive audits, enhancing compliance, and fostering collaboration across departments to mitigate risks and improve operational efficiency...
1 week ago
$125K - $150K *
Join us as a key legal advisor, shaping strategy and guiding executive leadership through complex regulatory and contractual matters while balancing legal risk with business objectives...
1 week ago
$87K - $100K *
Champion the finance operations for Taft-Hartley benefit funds, overseeing reporting, audits, and team development. Drive process improvements and ensure accuracy in financial reporting while liaising...
1 week ago
Cybersecurity Manager - Utilities Industry
$94K - $293K *
Drive cybersecurity transformation within Utilities, managing complex engagements, developing tailored strategies, and enhancing operational resilience to safeguard critical infrastructure and meet re...
Reposted 1 week ago
$108K *
The Registered Nurse (RN) position involves providing direct and indirect patient care in a specialty hospital setting, focusing on chronic, critically ill, and medically complex patients. The role in...
Reposted 1 week ago
Senior Technical Sales Manager
$128K - $213K *
Drive innovative technical solutions in power stability and electrical systems, engaging with customers and collaborating with sales teams to deliver tailored proposals that meet complex requirements...
1 week ago
Senior Budget Administrator - Clinical Trials
$100K - $161K *
Advance your career by coordinating clinical trial budgets and coverage analyses. Collaborate with stakeholders to ensure compliance and cost efficiency while mentoring junior staff and enhancing admi...
1 week ago
Configuration Management (CM) Engineer
$90K - $110K *
Grow your career with a pivotal role in configuration management, ensuring system stability and compliance. Collaborate across teams to track changes, maintain documentation, and support deployments i...
1 week ago
$80K - $96K *
Champion the safety of families by providing tailored home security solutions. Engage directly with customers, guiding them through personalized installations and earning uncapped commissions in a sup...
1 week ago
Senior Cybersecurity Engineer (Center of Excellence)
$131K - $219K *
Join a team that's redefining cybersecurity in the energy sector. You'll lead complex projects, develop standards, and automate processes to enhance efficiency and security across global Grid Automati...
1 week ago
Neuromuscular Account Manager - Mid-Atlantic
$155K - $210K *
Drive success by championing patient needs and executing strategic account plans. Leverage clinical expertise and business acumen to exceed sales goals while fostering relationships with key stakehold...
1 week ago
$142K - $237K *
Shape the global quality strategy for Power Sensing and Regulation, ensuring high standards across product lifecycles. Collaborate with cross-functional teams to drive continuous improvement and enhan...
1 week ago
$127K - $212K *
Champion secure architecture by conducting reviews and assessments for cloud and on-premise systems. Leverage your cybersecurity expertise to design solutions that align with security best practices a...
1 week ago
Application Engineer (Technical Sales) - Defense
$108K - $181K *
Create impactful technical solutions in military electrification projects. Collaborate with defense clients and provide expertise throughout the proposal process, ensuring compliance and mission effec...
Reposted 1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.