Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Senior Technical Program Manager, Infrastructure Programs
$130K - $170K *
Execute end-to-end digital onboarding of complex AI data center infrastructure, managing cross-functional teams to ensure timely delivery, stability, and optimization of high-performance systems for p...
Reposted 1 week ago
Principal Systems Studies Engineer - Protection
$120K - $145K *
Innovate solutions in power systems engineering by leading consulting initiatives, enhancing client relationships, and driving strategic growth in protection and control services while ensuring high-q...
1 week ago
Senior Operations Manager, Corrections
$100K - $120K *
Lead the charge in managing clinical operations for dialysis services, ensuring quality patient care, compliance, and operational efficiency across multiple facilities while fostering strong relations...
1 week ago
Manager - Special Investigations Unit
$110K - $150K *
Lead the operations of a Special Investigations Unit, managing a team of investigators to enhance fraud detection and prevention. Drive compliance, collaborate with stakeholders, and shape strategies...
1 week ago
Commercial Relationship Manager
$95K - $115K *
Empower client relationships and drive profitable growth through effective business development and strategic collaboration. Utilize your extensive banking expertise to enhance financial solutions for...
Reposted 1 week ago
$94K - $126K *
Join a team that's driving growth in military and government sectors by developing strategic sales capabilities and fostering strong customer relationships to maximize territory potential and ensure l...
1 week ago
$70K - $95K *
Join a dynamic team to empower associates and enhance member experiences. Drive strategic initiatives, foster collaboration, and embrace digital transformation while delivering exceptional results in...
1 week ago
$80K - $95K *
Unlock insights by leading advanced data analytics for federal programs. Collaborate with cross-functional teams to ensure compliance and data integrity while mentoring junior analysts and presenting...
1 week ago
$100K - $120K *
Lead EHS initiatives across multiple facilities, ensuring compliance and fostering a safety culture. Drive strategic planning, conduct inspections, and collaborate with teams to enhance environmental...
1 week ago
Principal Consultant - Power Energy Markets
$200K - $240K *
Advance expertise in energy markets by managing complex client engagements, developing strategic recommendations, and fostering client relationships. Utilize analytical skills to drive impactful solut...
1 week ago
$103K - $181K *
Optimize document control processes by leading the Information Branch, ensuring accurate and accessible records management for a major industrial program while coordinating with various stakeholders a...
1 week ago
$88K - $154K *
Optimize document management processes for a large-scale industrial project, ensuring accurate, secure, and accessible records throughout all project phases. Collaborate with multidisciplinary teams t...
1 week ago
$110K - $130K *
Unlock potential by leading a global accounting team, driving process improvements, and integrating AI solutions to enhance financial operations and reporting accuracy in a dynamic SaaS environment...
1 week ago
$95K - $115K *
Lead the charge in optimizing financial systems, enhancing automation, and improving reporting. Collaborate with Finance and IT to support core processes and drive continuous improvement within establ...
1 week ago
Wealth Advisory - Merger & Tuck-In Partnership Opportunities
$160K - $200K *
Grow your career with a leading RIA by transitioning your client base to a sophisticated platform. Leverage a collaborative team model to deliver comprehensive wealth management solutions for high-net...
1 week ago
Senior Implementation Consultant
$95K - $115K *
Lead the charge in implementing the Deacom ERP platform, driving customer success through expert consultation, project management, and tailored solutions. Collaborate with clients to enhance business...
1 week ago
$95K - $115K *
Join a dynamic team as a Senior Sensory Scientist, driving sensory science initiatives across Human Nutrition & Health. Lead studies, train teams, and collaborate with partners to enhance product qual...
1 week ago
Licensed Clinical Social Worker (Remote)
$78K - $92K *
Engage in impactful virtual counseling for patients with acute mental health conditions. Develop treatment plans, exercise clinical judgment, and collaborate with multidisciplinary teams to enhance be...
1 week ago
Clinical Psychologist (Remote)
$120K - $130K *
Shape the future of mental health care by providing virtual counseling and developing treatment plans for patients with acute conditions. Collaborate with medical professionals while ensuring adherenc...
1 week ago
$125K - $140K *
Drive impactful energy projects by managing schedules, coordinating teams, and analyzing risks. Leverage your expertise in project planning to ensure timely delivery and optimize performance across di...
1 week ago
$75K - $100K *
Join a dynamic team to drive project success from concept to completion. Collaborate with customers and internal teams to deliver tailored solutions, manage costs, and enhance processes in a fast-pace...
1 week ago
$80K - $140K *
Lead the charge in seamless M&A integrations, collaborating across teams to ensure operational continuity, regulatory compliance, and successful transitions while driving strategic initiatives and per...
1 week ago
$80K - $95K *
Transform the accounting function by overseeing monthly closes, ensuring compliance, and managing tax processes. Collaborate with finance leadership to drive accurate reporting and support strategic p...
1 week ago
$95K - $100K *
Transform virtual learning by leading strategy and development of innovative programs. Collaborate across teams to enhance educational experiences, ensuring quality and scalability while meeting diver...
1 week ago
Senior Executive Director Finance
$121K - $145K *
Strategize financial operations and enhance reporting accuracy while leading the finance team. Collaborate with senior leadership to drive financial sustainability and operational efficiency across bu...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.