Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Jobs in Missouri

Average Salary in USD

Average Salary: $114,671

Sort By: Relevance

$94K - $126K *

Accelerate growth in assigned territory by developing strategic sales capabilities, managing key accounts, and collaborating with team members to close sales opportunities while ensuring customer sati...

1 week ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$109K - $135K *

Lead measurement and optimization of media and shopper marketing investments. Collaborate with cross-functional teams to translate data into actionable insights that enhance marketing performance and...

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$154K - $225K *

Pioneer innovation in enterprise wireless solutions by leveraging expertise in Wi-Fi standards, technical marketing, and compelling content creation. Collaborate with teams to engage top-tier customer...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$90K - $110K *

Shape the future of technical content by building a robust function from the ground up, focusing on client engagement and leveraging emerging technologies to enhance understanding and communication...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$105K - $115K *

Engage with us to lead multiple client implementations, ensuring seamless transitions and high satisfaction. Collaborate cross-functionally, manage project timelines, and mentor team members while dri...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $100K *

Elevate your career by leading financial reporting and analysis for global Private Credit funds. Collaborate with a dedicated team to deliver innovative solutions and ensure compliance while maintaini...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$104K - $157K *

Transform engineering projects from concept to completion, ensuring timely delivery, quality, and safety. Collaborate with cross-functional teams to optimize processes and enhance performance in a dyn...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Optimize our software architecture as a senior engineer, leading the design, development, and maintenance of core applications while mentoring team members and enhancing product features for scalabili...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$110K - $130K *

Oversee compliance and risk management for branch teams, ensuring adherence to regulatory standards. Collaborate with leadership to enhance compliance culture and support client-focused solutions whil...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $180K *

Join us as a senior technology leader to define and govern enterprise architecture, ensuring alignment with strategic business objectives while leveraging AI for enhanced decision-making and execution...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Empower your career by managing complex projects from inception to completion. You'll oversee proposals, budgets, and team coordination, ensuring adherence to safety and quality standards while delive...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$86K - $146K *

Join us to execute and enhance partner operations, ensuring seamless workflows and data integrity. Collaborate with cross-functional teams to support sales and partners, driving efficiency and operati...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Transform the landscape of patient care by maximizing sales and awareness of specialized products. Collaborate with healthcare professionals to ensure compliance and enhance patient outcomes while man...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $125K *

Transform your career by leading financial modeling for multi-million-dollar real estate projects. Drive client relationships, manage budgets, and create impactful proposals while collaborating with c...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $180K *

Grow your career by driving strategic sales in a dynamic cybersecurity landscape, collaborating with leaders and partners to expand market presence and achieve impressive business growth. Engage with...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Accelerate progress at the Memphis Manufacturing Site by leading the Maintenance Department to enhance asset reliability, optimize equipment performance, and drive continuous improvement initiatives...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$170K - $195K *

Join a team that's dedicated to optimizing global power generation operations. You'll support fleet management, enhance O&M standards, and drive continuous improvement initiatives across a diverse por...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$60K - $120K *

Take ownership of customer relationships to drive upgrades and maximize value. Engage with existing clients, manage the full sales cycle, and build trust to enhance their experience with our platform...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Join a team that's shaping intuitive AI experiences through user-centered design. Collaborate with cross-functional teams to translate complex AI capabilities into accessible solutions that drive busi...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $130K *

Shape the future of our sales strategy by developing plans that align with business objectives and drive measurable goals, ensuring effective implementation and collaboration across regional teams to...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Shape the future of health technology by driving regulatory strategies for innovative lab testing, imaging, and AI products. Collaborate with cross-functional teams to ensure compliance and accelerate...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$151K - $177K *

Join a dynamic team to shape compelling narratives at the intersection of technology and consumer engagement. Drive impactful PR initiatives, build media relationships, and elevate brand visibility th...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$130K - $150K *

Shape the future of communication by leading consultative sales cycles across mid-market and enterprise segments. Drive full sales processes with a focus on value-based selling and collaboration with...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$72K - $108K *

Optimize vehicle performance by diagnosing and repairing complex systems, ensuring high-quality workmanship and customer satisfaction through efficient service and technician support...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$80K - $95K *

Drive operational excellence as you lead a specialized tool room team, overseeing die design, fabrication, and maintenance. Foster a culture of safety and continuous improvement while managing resourc...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.