Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Staff Product Manager, Pricing
$168K - $210K *
Transform pricing strategies by leading cross-functional teams to enhance decision-making and model deployment. Drive the evolution of pricing platforms, integrating advanced AI to streamline workflow...
1 week ago
$120K - $150K *
Elevate your career by driving enterprise sales for innovative solutions. Engage with multinational accounts, build strategic relationships, and lead complex negotiations to unlock growth opportunitie...
1 week ago
$110K - $140K *
Grow your career with us as you lead accounting operations, manage audits, and contribute to financial strategies while collaborating with senior leadership in a remote role...
Reposted 1 week ago
$150K - $180K *
Shape strategic sales initiatives targeting Fortune 2000 accounts. Drive complex sales cycles, engage with C-suite leaders, and leverage AI solutions to meet revenue goals while building a robust pipe...
1 week ago
$90K - $110K *
Empower quality assurance by developing AI-assisted automated tests, integrating them into CI/CD pipelines, and collaborating with cross-functional teams to enhance software reliability and release ef...
1 week ago
FlexPoint Sales Account Manager - California (Base Pay Plus Commission)
$59K - $118K *
Drive revenue growth by managing customer accounts and pursuing new sales opportunities. Utilize consultative strategies to build relationships and meet sales quotas while serving as a trusted advisor...
Reposted 1 week ago
$114K - $167K *
Engineer innovative ERP solutions by analyzing complex business processes, defining architecture, and leading integration efforts to optimize performance and ensure compliance. Drive impactful customi...
1 week ago
Account Manager-Employee Group Benefits
$76K - $129K *
Join us to build strong relationships with key policyholders through proactive communication and skilled negotiation. You'll bridge clients and the home office, tackling concerns and driving improveme...
1 week ago
Manager, Firewall Policy Engineering
$102K - $190K *
Lead and develop a high-performing team in firewall security engineering, ensuring consistent implementation of security controls while balancing operational demands and strategic initiatives for ente...
1 week ago
Associate - Financial Planning & Analysis (FP&A)
$80K - $95K *
Empower your career by driving financial insights and analytics. Collaborate across teams to transform data into strategic decisions, enhancing growth and efficiency in a dynamic environment. Join us...
1 week ago
Senior Solutions Engineer (NY/NJ/PA)
$163K - $245K *
Optimize enterprise application delivery and security solutions by partnering with key stakeholders to design and implement modern architectures across multi-cloud environments, driving innovation and...
1 week ago
Field Service Engineer - Proton Therapy - Voorhees, NJ
$71K - $98K *
Join a team that's dedicated to providing exceptional customer support and maintaining the performance of advanced Proton Therapy Systems. This role involves hands-on technical expertise and collabora...
1 week ago
$89K - $165K *
Shape innovative engineering solutions by applying advanced design techniques and conducting complex analyses. Collaborate with cross-functional teams to enhance product development and ensure high-qu...
1 week ago
$89K - $165K *
Engineer innovative solutions by applying advanced design techniques to complex electrical systems, conducting technical analyses, and collaborating with cross-functional teams to enhance product deve...
1 week ago
Credit Advisor - Global Wealth & Investment Management
$126K - $250K *
Shape the future of Commercial Real Estate lending by developing strategic credit relationships, driving revenue growth, and managing portfolios while collaborating with Advisors and risk teams to del...
1 week ago
Remote Sr. Technical Trainer - Operational Excellence Champion
$130K - $150K *
Join a team that's dedicated to operational excellence by developing training programs and mentoring technicians in Power Systems. Drive improvements and standardization across regions while enhancing...
1 week ago
$140K - $215K *
Join a team that's at the forefront of cyber investigations, leading a skilled pod to combat AI misuse. Drive complex attribution, mentor investigators, and enhance automated detection models while en...
1 week ago
$82K - $172K *
Innovate your career as you design and maintain mission-critical software for defense financial systems. Lead a growing team, integrate AI capabilities, and ensure compliance in both classified and un...
1 week ago
$83K - $93K *
Take ownership of complex CNC machine tool repairs, installations, and customer training. Utilize advanced mechanical and electronic troubleshooting skills while collaborating effectively with clients...
Reposted 1 week ago
Enterprise Architect for Finance & Corp Functions
$139K - $232K *
Unlock potential by providing enterprise architecture leadership for Corporate Functions, focusing on Finance and supporting areas. Shape technology strategies and roadmaps to enhance financial manage...
1 week ago
Quality Data & Finished Goods Specification Manager
$90K - $110K *
Optimize the quality assurance process by leading data analytics and specification development. Drive actionable insights from complaints and non-conformance data while ensuring compliance across manu...
Reposted 1 week ago
Program Manager, Insurance Software Implementation
$125K - $165K *
Join a team that's redefining insurance technology delivery by leading SaaS implementation programs. This hands-on role combines project management with team leadership to ensure successful client out...
1 week ago
Enterprise Account Director - US Large Law Firms
$240K - $300K *
Drive revenue growth by engaging top-tier law firms, cultivating relationships, and executing strategic sales initiatives. Collaborate with leadership to exceed sales targets and enhance market presen...
1 week ago
Senior Director, Patient Experience Center of Excellence
$156K - $202K *
Elevate patient experiences by leading strategic initiatives in governance, intelligence, and hospitality excellence. Drive performance improvement and operational consistency across healthcare servic...
1 week ago
Product Manager II, Wallets and DeFi
$144K - $170K *
Shape the future of crypto infrastructure by leading the Flexible Custody roadmap, collaborating with cross-functional teams to deliver innovative custody and DeFi solutions for fintechs and corporate...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.