Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$120K - $130K *
Manage strategic accounts within the Life Sciences sector, driving growth by cultivating customer relationships and identifying new business opportunities. Leverage industry knowledge to ensure alignm...
Reposted 1 week ago
Regional Sales Manager - Southeastern US
$100K - $130K *
Take ownership of sales within a key territory, identifying opportunities and nurturing relationships with clients to drive business growth and exceed sales goals through strategic engagement and effe...
Reposted 1 week ago
$150K - $180K *
Drive exceptional support experiences globally, leading a high-performing team to enhance operational efficiency and scale offerings as our customer base and product suite expand...
Reposted 1 week ago
Digital Sales Director - California
$90K - $130K *
Drive revenue growth by developing strategic sales plans and building client relationships in the dynamic Connected TV advertising landscape. Leverage industry knowledge to identify opportunities and...
1 week ago
Sr. Account Manager - Renewals/Expansion
$140K - $175K *
Join a dynamic team as you drive renewals and expansion for managed sales customers. Leverage executive relationships and strategic planning to enhance account growth while collaborating with cross-fu...
1 week ago
MIS Product Specialist - Spinning Disk Confocal Systems - West
$96K - $120K *
Champion the growth of SPINNING Systems by leveraging technical expertise, driving sales initiatives, and collaborating across teams to enhance customer engagement and market presence in the life scie...
Reposted 1 week ago
$150K - $240K *
Develop innovative PCB layouts and improve product designs by collaborating with cross-functional teams. Ensure high quality and compliance throughout the engineering and manufacturing process, while...
Reposted 1 week ago
$70K - $94K *
Elevate your career by leading innovative paid media initiatives, optimizing campaigns, and exploring emerging channels to enhance enrollment strategies. Collaborate cross-functionally to drive perfor...
1 week ago
Territory Manager - Remote (MN/ND/SD)
$88K - $105K *
Join a team that accelerates growth in the Electric Utility sector by building robust relationships, driving sales strategies, and expanding market presence across multiple states. Ideal for motivated...
Reposted 1 week ago
Global Technology Engineer - Household Care & Germ Protection - Processing
$148K - $222K *
Optimize global processing equipment standards for Household Care & Germ Protection. Lead technical expertise, ensure compliance, and drive CAPEX project delivery across regions while fostering cross...
Reposted 1 week ago
$162K - $185K *
Drive strategic product development to meet growth goals, prioritizing user impact and results while collaborating with cross-functional teams to deliver innovative solutions that resonate with both B...
Reposted 1 week ago
$110K - $130K *
Transform the cybersecurity landscape by driving revenue growth and building strong customer relationships in the mid-market segment. Leverage consultative selling and AI-driven solutions to engage te...
1 week ago
$95K - $115K *
Optimize financial reporting and internal controls while collaborating with departmental managers. Drive strategy and continuous improvement initiatives, ensuring alignment with corporate goals and co...
Reposted 1 week ago
Medical Review Nurse II - SNF/MDS Auditor
$90K - $105K *
Tackle medical claims audits in a dynamic remote environment, collaborating with a skilled team to ensure compliance and accuracy in Skilled Nursing Facility reviews while enhancing audit processes an...
1 week ago
Senior Vice President, Capital Project Management and Execution
$180K - $220K *
Lead the charge in delivering a $3.2B capital program across multiple regions. Ensure projects are executed safely, on schedule, and within budget while collaborating with key stakeholders to advance...
Reposted 1 week ago
VP Business Development-Platform System Integration
$170K - $200K *
Lead the charge in driving business development for complex platform systems, ensuring profitable bookings through strategic engagement, opportunity qualification, and proposal execution while fosteri...
Reposted 1 week ago
$95K - $115K *
Advance the procurement team by leading subcontract negotiations, ensuring compliance, and fostering supplier relationships to deliver quality materials for engineering development programs...
Reposted 1 week ago
$88K - $105K *
Engage in the execution and management of multifaceted projects within a complex program, ensuring compliance with contract standards while enhancing customer relations and delivering technical suppor...
Reposted 1 week ago
$108K - $130K *
Shape the future of our operations by guiding an empowered team to achieve excellence in safety, quality, and efficiency while fostering community relationships and driving continuous improvement in o...
Reposted 1 week ago
$93K - $125K *
Drive reliability engineering initiatives across programs, collaborating with teams to enhance system performance and reduce risks. Lead analyses, manage documentation, and ensure compliance with indu...
1 week ago
$140K - $175K *
Shape technical innovation by leading cross-team efforts in system architecture and development. Drive scalable improvements, mentor peers, and influence business outcomes while ensuring long-term mai...
1 week ago
$300K - $500K *
Champion innovation by architecting and developing high-performance, real-time trading web apps. Leverage your expertise to enhance user experience and drive product evolution in a dynamic, collaborat...
1 week ago
$64K - $102K *
Elevate network performance by deploying and optimizing voice solutions, ensuring 99.999% uptime. Collaborate on network planning and security, while providing expert support and documentation for com...
Reposted 1 week ago
$228K - $364K *
Lead the charge in managing end-to-end PMC services for a high-value program, driving operational improvements and strategic initiatives to enhance efficiency, accountability, and customer experience...
1 week ago
$60K - $120K *
Empower growth by engaging existing customers, identifying upgrade opportunities, and managing the full sales cycle. Build trust with small business owners while driving revenue through effective outr...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.