Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Jobs in Missouri

Average Salary in USD

Average Salary: $114,671

Sort By: Relevance

$111K - $167K *

Elevate customer success by owning strategic relationships and technical solutions. Drive adoption and outcomes for a portfolio of accounts, collaborating across teams to ensure seamless implementatio...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$160K *

Join a team that's redefining sales through consultative approaches. Leverage your emotional intelligence and communication skills to guide homeowners in making informed decisions, ensuring a seamless...

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$123K - $135K *

Engage in a growth-focused role managing existing accounts, driving renewals and expansion. Collaborate with teams to identify opportunities, ensure customer satisfaction, and achieve revenue goals wh...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $232K *

Lead transformative SAP solutions in manufacturing, optimizing processes and driving innovation. Collaborate with teams to deliver value-driven results, leveraging deep expertise in SAP S/4HANA and bu...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $150K *

Join a team that's driving innovative demand generation strategies. You'll lead integrated campaigns, collaborate across departments, and optimize performance to generate qualified leads and pipeline...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$105K - $115K *

Empower institutional compliance by leading civil rights, Title IX, and accessibility initiatives. Collaborate with diverse stakeholders to enhance inclusion, oversee investigations, and ensure adhere...

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$94K - $133K *

Unlock potential by managing and enhancing partnerships within the Technology Partner Community, guiding software partners through onboarding and integration processes to maximize the value of HCM and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$82K - $150K *

Accelerate growth by driving new customer acquisition and expanding market share in the dental implant sector. Leverage your sales expertise to build relationships, convert competitive accounts, and p...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$82K - $150K *

Join a team that's driving growth in the dental implant market by aggressively prospecting and converting new customers. Leverage your sales expertise to expand market share and position value-oriente...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $105K *

Lead the governance of billing systems in SAP, ensuring accuracy and compliance with tariffs across jurisdictions. Collaborate with multiple teams on updates, testing, and system enhancements for util...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$210K - $300K *

Partner with us to drive strategic sales initiatives, cultivate CxO relationships, and identify growth opportunities, all while enhancing customer satisfaction and delivering impactful business outcom...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$138K - $185K *

Transform your career by leading enterprise data and AI architecture initiatives. Collaborate with cross-functional teams to drive technology adoption and ensure alignment with business needs while in...

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$110K - $130K *

Shape the future of healthcare finance by driving strategic insights, pricing models, and financial frameworks that support sustainable growth and influence executive decision-making across cross-func...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $169K *

Drive successful project execution by managing capital projects from concept to completion, ensuring adherence to design, scope, and milestones while coordinating with clients and teams for optimal re...

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$84K - $107K *

Support our team as a Senior Human Resources Generalist, overseeing employee relations, benefits, and recruitment in a factory setting. Collaborate on community outreach and wellness programs while en...

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$80K - $95K *

Lead the charge in optimizing plant operations through data analysis, loss reduction, and employee training. Drive continuous improvement initiatives to enhance performance metrics and foster a cultur...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$195K - $225K *

Drive security innovation by shaping technical strategies and frameworks that protect sensitive data and systems. Collaborate across teams to embed security practices, mentor engineers, and ensure com...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$100K - $125K *

Join our dynamic team to develop innovative sourcing strategies, lead supplier negotiations, and drive value creation within the Americas, contributing significantly to our growth and sustainability g...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Empower your career as a Sales Manager in the Specialty Fluids sector, driving growth through strategic account management and lead generation while collaborating with diverse teams across North Ameri...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $130K *

Lead diverse engineering teams in delivering innovative water and wastewater projects. Oversee execution, manage budgets, and develop client relationships while ensuring high-quality standards and men...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$80K - $95K *

Join us to lead a dynamic team in optimizing revenue cycle operations for multiple clients. Drive continuous improvement and ensure client satisfaction while managing performance metrics and fostering...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $125K *

Champion customer quality initiatives by collaborating with cross-functional teams to enhance satisfaction, resolve issues, and drive continuous improvement in the Data Center Chiller business. Engage...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Drive growth by building and scaling credit card acquisition channels through innovative affiliate partnerships, targeted paid search, and social programs, while collaborating with cross-functional te...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Lead plant operations by driving continuous improvement and ensuring safety. Oversee production, engineering, and finance while fostering team development and meeting customer needs. Shape the facilit...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Pioneer effective operations by leading teams in specialty construction projects, ensuring safety, quality, and efficiency. Collaborate with stakeholders to navigate challenges and uphold company valu...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.