Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Jobs in Missouri

Average Salary in USD

Average Salary: $114,671

Sort By: Relevance

$87K - $122K *

Join a dedicated outpatient dialysis team to provide compassionate care for patients with kidney conditions. Collaborate with clinical staff, educate families, and manage treatment plans in a fast-pac...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$70K - $119K *

Optimize operational efficiency by analyzing performance metrics, supporting training, and enhancing tool adoption within the Business Development Representative organization to drive productivity and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$170K - $205K *

Drive the development of safety-critical autonomous systems, ensuring robust safety performance through hazard analysis and collaboration with cross-functional teams. Contribute to innovative solution...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$110K - $130K *

Lead transformative real estate development projects across hospitality, residential, and retail sectors. Oversee all phases from acquisition to completion, ensuring alignment with financial and opera...

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$90K - $110K *

Elevate your career by managing accounting activities, ensuring compliance, and collaborating across teams to enhance financial accuracy and internal controls in a dynamic environment...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$95K - $115K *

Contribute to revenue growth by selling innovative traffic management solutions to government agencies. Build strategic partnerships, identify opportunities, and execute sales strategies to meet ambit...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

$100K - $120K *

Transform traffic management by driving revenue through strategic partnerships with government agencies. Collaborate with teams to identify opportunities, tailor solutions, and achieve growth objectiv...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

$100K - $120K *

Shape the future of traffic management by driving revenue through strategic partnerships with government agencies. Cultivate relationships, identify opportunities, and execute sales strategies to meet...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

$272K - $431K *

Join a team that's redefining cloud-native technologies by managing innovative engineering efforts in container orchestration and GPU acceleration, ensuring seamless integration across platforms while...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Unlock potential by managing financial accuracy and insights, overseeing month-end close, budgeting, and project accounting. Collaborate closely with the Controller to ensure compliance and streamline...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$175K - $225K *

Transform your career by leading the engineering design of a cutting-edge SCADA program for a hybrid energy facility. Collaborate with multidisciplinary teams to ensure seamless integration and compli...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$80K - $95K *

Drive the execution of large-scale field operations, ensuring projects meet budget, schedule, and safety standards while mentoring team members and fostering strong relationships with clients and part...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead plant operations to drive strategic initiatives, enhance safety, and optimize performance. Foster team development and implement best practices to achieve corporate objectives while ensuring comp...

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$150K - $180K *

Transform your career by driving growth in commercial real estate financing. This role focuses on originating and structuring loans while building strong relationships with clients and industry profes...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the charge in managing complex implementations for enterprise clients, ensuring a seamless onboarding experience. Collaborate cross-functionally to drive customer success and optimize the use of...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$115K - $120K *

Drive operational excellence as a hands-on leader in a high-volume warehouse, overseeing logistics, pallet repair, and team development. Ensure safety, productivity, and quality while fostering a cult...

1 week ago

  •   5 - 7 years exp.  •   Transportation

$132K - $302K *

Unlock potential by delivering innovative Salesforce Marketing Cloud solutions that enhance customer engagement across Financial Services. Collaborate with diverse teams to optimize data-driven market...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$116K - $165K *

Drive engineering excellence by leading the design and integration of marine vessels. Collaborate across teams to ensure compliance and quality in hull structure, propulsion, and auxiliary systems, wh...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$40K - $120K *

Unlock potential by managing the complete automotive sales process, providing exceptional customer service, and building lasting relationships to drive sales and referrals in a dynamic dealership envi...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$144K - $242K *

Lead the development of an AI-driven seller experience, shaping product strategy and engaging homeowners throughout their selling journey. Collaborate across teams to define success metrics and protot...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$91K - $124K *

Join a team that's dedicated to delivering compassionate dialysis care. In this role, you'll monitor patient health, educate individuals, and collaborate with a skilled team in a fast-paced outpatient...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Manage a comprehensive food and beverage program across multiple properties, ensuring exceptional guest experiences and adherence to health standards. Lead teams to exceed brand expectations while dri...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$89K - $120K *

Transform your sales career by driving revenue growth through strategic partnerships. Manage the full sales cycle, collaborate with teams, and leverage your expertise in cloud computing to attract and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$82K - $123K *

Drive innovative software solutions by integrating AI capabilities and enhancing user experiences. Collaborate with teams to develop, test, and implement applications, ensuring quality and efficiency...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$88K - $105K *

Contribute to organizational success by partnering with leaders to enhance HR practices, drive employee engagement, and support growth initiatives, ensuring a positive experience throughout the employ...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.