Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Business Central Implementation Consultant
$120K - $140K *
Transform your career by leading Business Central ERP implementations. Collaborate with clients and teams to deliver tailored solutions, ensuring project success from kickoff to go-live. Drive innovat...
1 week ago
Psychiatric Nurse Practitioner (Synchronous AHPC) - Remote
$171K - $246K *
Shape the future of mental health care by providing remote psychiatric assessments and treatments. Deliver compassionate support to diverse clients, focusing on adults and adolescents, while collabora...
Reposted 1 week ago
Associate/Sr. Associate, Academic Partnering, Asset Acquisition
$130K - $150K *
Advance innovative therapeutic programs targeting genetically driven diseases through strategic sourcing, relationship building, and cross-functional collaboration, ensuring a patient-first approach i...
1 week ago
$115K - $125K *
Transform client relations by managing multiple clinical accounts, ensuring superior service quality, and driving financial success through strategic planning and effective project management...
1 week ago
$105K - $160K *
Empower channel partners by providing technical leadership and solution architecture expertise focused on HPE Aruba technologies. Drive sales engagement and architect resilient infrastructure solution...
1 week ago
$138K - $240K *
Join a team that's driving supplier program execution and partner growth. Lead sales strategies, manage a high-performing team, and cultivate key relationships to achieve ambitious sales goals in the...
1 week ago
Supplier Manager - Security II
$102K - $187K *
Lead the charge in strategic supplier management, driving growth and operational excellence through executive engagement, market development, and partner ecosystem initiatives while mentoring teams an...
1 week ago
$280K - $400K *
Empower engineering excellence by leading a growing team to deliver high-quality software solutions while fostering collaboration across teams and ensuring operational scalability...
Reposted 1 week ago
Senior Sales Operations Transformation & Managed Services Leader
$132K - $245K *
Elevate Sales Operations by leading transformation initiatives, optimizing processes, and implementing AI-driven solutions to enhance efficiency and drive revenue growth. Collaborate with clients to r...
1 week ago
Dealer Development Manager (Las Vegas, NV)
$80K - $95K *
Champion growth by developing and maintaining dealer partnerships, driving sales, and enhancing customer satisfaction in the auto finance sector. Leverage market insights to optimize performance and e...
1 week ago
$80K - $200K *
Unlock new opportunities by engaging small business owners through face-to-face sales. Drive membership growth with a focus on prospecting, building relationships, and delivering tailored solutions in...
1 week ago
$157K - $283K *
Elevate your career by managing complex R&D projects in wireless communication, focusing on 6G security for military applications. Collaborate with multidisciplinary teams to deliver innovative soluti...
1 week ago
$89K - $142K *
Engage with clients as a Territory Manager, driving sales growth and maintaining strong relationships in the industrial filtration sector. Collaborate across divisions to meet customer needs and execu...
Reposted 1 week ago
$115K - $130K *
Champion innovative design solutions by integrating AI into user experiences, driving product evolution through collaboration with cross-functional teams, and enhancing customer engagement across dive...
1 week ago
$136K - $181K *
Take ownership of CRA management by leading teams, developing metrics, and ensuring compliance with monitoring standards. Drive continuous improvement and optimize effectiveness across the Site Manage...
1 week ago
Technical Product Manager, Core Banking
$120K - $145K *
Lead the charge in transforming our core banking platform by driving technical architecture and integration. Collaborate with cross-functional teams to deliver scalable solutions that enhance operatio...
1 week ago
$90K - $110K *
Develop intuitive, user-centered designs for digital products, collaborating with cross-functional teams to enhance customer experiences. Own the design process from concept to implementation, leverag...
1 week ago
Regional Account Manager- Utility (NW Territory)
$75K - $105K *
Champion growth by building relationships and driving utility sales in a dynamic territory. Leverage technical expertise to manage complex sales cycles and deliver impactful solutions, ensuring custom...
1 week ago
Sr Area Business Director, West
$160K - $190K *
Lead the charge in driving growth by managing a high-performing sales team, collaborating across functions, and executing strategic initiatives to enhance commercial success in the Hematology sector...
1 week ago
Solution Architect (P&C insurance domain)
$135K - $160K *
Lead the charge in architecting a cutting-edge Commercial Lines insurance platform, focusing on microservices and event-driven architecture. Collaborate with cross-functional teams to define and deliv...
1 week ago
Physician - Psychiatrist (Substance Use Disorders)
$180K - $220K *
Innovate psychiatric care by leading evaluations, treatments, and documentation. Collaborate with residents and nurse practitioners while ensuring compliance with regulations. Participate in on-call r...
1 week ago
$92K - $115K *
Champion client performance by managing Meta ad campaigns, optimizing strategies, and crafting compelling direct-response content to enhance engagement and retention across multiple accounts...
Reposted 1 week ago
Implementation Consultant, Audit
$100K - $120K *
Build customer relationships by delivering seamless onboarding and maximizing platform adoption, driving value realization through proactive guidance and cross-team collaboration...
Reposted 1 week ago
Manager, Technology, Data and AI Advisory, Energy & Utilities
$125K - $150K *
Transform the energy & utilities landscape by leading OT and infrastructure workstreams throughout the private equity investment lifecycle, driving diligence, integration, and value creation for criti...
1 week ago
Director, Institute for Cybersecurity - College of Business and Computing
$100K - $120K *
Transform cybersecurity education by leading strategic initiatives, fostering partnerships, and enhancing community engagement. Drive program development and research to prepare students for dynamic c...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.