Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Product Manager, Provider Marketplace
$120K - $145K *
Join a dynamic team to drive the development of a cutting-edge marketplace, enhancing provider products and economic incentives while collaborating closely with engineering and operations to transform...
1 week ago
Clinical Informatics & Ontology Lead
$120K - $145K *
Lead the design and governance of clinical ontologies and terminology services, ensuring data quality and alignment with product needs. Collaborate cross-functionally to enhance data normalization and...
1 week ago
Remote Business Process Consultant (VA ESOM)
$125K - $145K *
Unlock potential by bridging business needs with technical solutions. Collaborate with stakeholders to define requirements, manage product backlogs, and ensure successful delivery of ServiceNow capabi...
1 week ago
Supervisor of SQL Server Database Services #5-6-099
$80K - $95K *
Lead and inspire a team managing SQL Server databases in cloud and on-prem environments. Oversee project deliverables, budget tracking, and cross-team collaboration to enhance database services for st...
1 week ago
Energy Analytics Manager, Clean Energy
$110K - $130K *
Transform the renewable energy landscape by managing data portfolios, analyzing project performance, and enhancing financial reporting. Collaborate with cross-functional teams to drive strategic energ...
1 week ago
Nurse Practitioner - NP - Fenton
$95K - $115K *
Join a team that's dedicated to providing exceptional clinical care and therapeutic services. You'll treat patients, uphold professional standards, and contribute to a mission-driven environment focus...
1 week ago
Principal Security Software Engineer, PKI and Secrets Management
$201K - $309K *
Elevate security standards by leading the development of innovative software solutions. Collaborate with cross-functional teams to integrate robust security measures, ensuring the integrity of applica...
1 week ago
Technical Relationship Manager (Hybrid - Bank of America)
$110K - $130K *
Join us to drive strategic relationships with enterprise customers, optimizing IGEL technology solutions. This hands-on role balances technical expertise with customer management, focusing on the Fina...
1 week ago
$160K - $200K *
Elevate the People function as a strategic partner, driving talent strategy, organizational design, and culture in a dynamic, global environment. Shape leadership effectiveness and enhance employee ex...
1 week ago
$94K - $157K *
Unlock potential by joining our team as a Data Analyst, where you'll leverage your expertise in data manipulation and visualization to support key Federal clients, driving impactful solutions through...
1 week ago
Senior Substation Commissioning Specialist
$140K - $185K *
Innovate the future of energy by leading the commissioning of electrical substations. Oversee testing, validation, and project management while collaborating with diverse teams across the nation to en...
1 week ago
Federal Developer - AWS/Amazon Connect
$110K - $170K *
Shape the future of cloud solutions by architecting and optimizing advanced contact centers. Collaborate with cross-functional teams to leverage AI and AWS technologies, enhancing customer experiences...
1 week ago
Information Security Analyst II (Remote)
$73K - $95K *
Advance security measures by monitoring, analyzing, and remediating risks across the enterprise. Collaborate with IT teams to enhance security posture, focusing on threat detection, vulnerability mana...
1 week ago
Pharmacy Benefit Management Examiner
$95K - $140K *
Lead PBM compliance audits, ensuring adherence to state regulations and industry standards. Supervise examiners, manage client relationships, and adapt to a fast-paced environment while driving progra...
1 week ago
$95K - $115K *
Champion operational excellence by leading multi-departmental teams in healthcare services. Drive strategic initiatives, optimize performance, and ensure compliance while enhancing patient satisfactio...
1 week ago
$150K - $180K *
Lead and develop a high-performing team of enterprise account executives, driving revenue growth and shaping sales strategies in the finance sector. Engage with senior decision-makers and manage compl...
1 week ago
$110K - $130K *
Unlock potential by leading tax engagements, mentoring teams, and delivering exceptional client service. Thrive in a collaborative environment while managing multiple projects and driving growth for p...
1 week ago
$176K - $220K *
Lead the charge in driving sustainable revenue growth by managing a high-performing team of Account Executives focused on acquiring new clients in the financial sector, ensuring effective sales execut...
1 week ago
Senior Professional Services DevOps Engineer
$150K - $180K *
Join a team that's shaping the future of DevOps by designing and implementing CI/CD pipelines with cutting-edge technologies. Collaborate with customers and cross-functional teams to enhance their Dev...
1 week ago
$80K - $95K *
Shape your career by leading integrated marketing campaigns that drive customer engagement and new business growth. Collaborate with cross-functional teams to enhance customer adoption and pipeline de...
1 week ago
Field Marketing Manager - Central
$88K - $105K *
Champion regional marketing initiatives by aligning with sales to create impactful programs that drive pipeline growth and enhance community engagement. Manage budgets, logistics, and reporting to ens...
1 week ago
$80K - $95K *
Lead construction project engineering efforts, ensuring compliance with regulations and quality standards. Collaborate with government personnel to oversee project delivery, manage contract administra...
1 week ago
Transportation Consultant - Final Mile
$68K - $97K *
Lead operational stability and process standardization for transportation across multiple facilities. Collaborate with planners and logistics partners to enhance delivery performance and resolve disru...
1 week ago
Sr. Manufacturing Mechanical Engineer
$88K - $105K *
Join a dynamic team to design, install, and improve manufacturing equipment and processes, focusing on metal-forming operations. This hands-on role combines engineering expertise with fieldwork to enh...
1 week ago
$110K - $130K *
Join a team that's dedicated to enhancing enterprise IAM governance. You'll oversee access reviews, ensure compliance, and collaborate with cross-functional teams to strengthen security controls and d...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.