Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Jobs in Missouri

Average Salary in USD

Average Salary: $114,671

Sort By: Relevance

$100K - $140K *

Lead full lifecycle recruitment for Sales, ensuring a world-class candidate experience while collaborating with leadership to align hiring strategies and attract top talent in a fast-paced, high-growt...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$230K - $290K *

Advance your career by leading procurement strategies that drive efficiency and value creation. Collaborate cross-functionally to optimize processes and foster a culture of operational excellence whil...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$130K - $160K *

Elevate customer solutions by providing architectural expertise and innovative strategies. Collaborate with account teams and partners to deliver high-value technical consulting and drive competitive...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$72K - $176K *

Help us enhance electric distribution systems by conducting power flow studies, developing solutions, and collaborating with teams to ensure reliability and compliance in our planning processes...

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$85K - $111K *

Optimize infrastructure solutions by leading cross-functional teams to design, implement, and support resilient systems. Collaborate with diverse stakeholders to ensure timely delivery and operational...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Drive enclosure commissioning and consulting growth while enhancing construction quality. Collaborate with multidisciplinary teams to ensure enclosures are built right the first time, delivering excep...

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$150K - $180K *

Transform the SAP sales landscape by leveraging your extensive network and expertise to drive new business acquisition in the manufacturing sector. Own the full sales cycle, from lead generation to cl...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Empower the development of consumer banking products by providing expert legal guidance throughout their lifecycle, ensuring compliance with regulations and collaborating with cross-functional teams t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$120K - $145K *

Shape the future of data governance by leading a team to manage third-party data compliance, ensuring operational excellence and regulatory adherence while fostering collaboration across business unit...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Join a team that's transforming go-to-market strategies through AI-driven growth experiments. Leverage your engineering skills to build impactful agents and optimize sales processes, driving measurabl...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$89K - $148K *

Lead the charge in overseeing IT project management for cloud migrations, ensuring effective communication and governance while driving project success and stakeholder alignment in a dynamic environme...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $200K *

Join a team that's driving global tax and treasury strategies for a high-growth enterprise software company. You'll manage compliance, cash management, and cross-functional partnerships to support int...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$250K - $300K *

Lead the charge in driving enterprise sales by collaborating with Microsoft teams to identify and capitalize on AVD opportunities. Leverage your expertise in VDI and EUC technologies to foster relatio...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Join a team that's dedicated to ensuring supplier compliance and quality in the nuclear industry. Leverage your expertise in quality assurance to evaluate supplier programs, conduct audits, and mainta...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$146K - $183K *

Empower growth by leading full-cycle executive searches for Director and VP roles, focusing on Engineering, Product, Design, and Data. Collaborate with senior leaders to attract top talent and enhance...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$148K - $248K *

Unlock potential by leading a dynamic team focused on driving growth in financial services. You'll develop strategies, build relationships, and enhance productivity for major institutions, ensuring al...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$93K - $126K *

Elevate your career by supporting diverse system studies in renewable energy projects. Collaborate in a dynamic environment, delivering technical expertise and leveraging advanced tools to ensure safe...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$88K - $105K *

Lead product marketing initiatives by crafting compelling messaging and strategies that drive customer engagement and adoption. Collaborate cross-functionally to ensure alignment and measure performan...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$130K - $150K *

Transform the Salesforce landscape by designing and delivering innovative solutions. Leverage your coding expertise and declarative skills to create scalable applications that meet complex business ne...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$116K - $229K *

Lead strategic initiatives as a Senior Consultant, driving digital marketing growth and operational excellence. Collaborate across teams to develop actionable insights and enhance client performance i...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$116K - $229K *

Transform client strategies by leading digital marketing initiatives, analyzing market trends, and collaborating across teams to drive growth and operational excellence. Leverage data insights to enha...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$330K - $500K *

Shape the future of content discovery by leading product operations and program management. Drive efficiency and innovation across teams, ensuring seamless collaboration and execution of high-impact i...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$200K - $250K *

Optimize your career as a full-stack software engineer, collaborating with agile teams to enhance high-transaction e-commerce applications. Drive quality, mentor peers, and innovate solutions that ele...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Drive customer success by building relationships, enhancing product adoption, and delivering value in a dynamic SaaS environment. Collaborate cross-functionally to ensure client satisfaction and reten...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Join a team that's dedicated to ensuring construction quality and compliance. Oversee projects, conduct inspections, and collaborate with government personnel to uphold standards in workmanship, mater...

1 week ago

  •   5 - 7 years exp.  •   Technical Services

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.