Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$72K - $94K *
Contribute to program success by planning, coordinating, and executing activities. Collaborate with teams and stakeholders to monitor progress, manage risks, and analyze data, ensuring objectives are...
1 week ago
$100K - $120K *
Partner with us to enhance relationships with executive partners, enabling pipeline growth and revenue generation. Leverage cross-functional collaboration while managing multiple engagements, driving...
Reposted 1 week ago
Sr. Director, Business Development
$150K - $180K *
Transform client engagement by driving growth in untapped markets, shaping impactful solutions, and delivering measurable results. Collaborate with diverse teams to connect client needs with innovativ...
1 week ago
Senior Microgrid Automation Engineer
$107K - $195K *
Join a team that's shaping the future of microgrid automation and renewable energy. Leverage your expertise in control systems and collaborate on innovative projects that drive sustainable energy solu...
1 week ago
Director, Digital Manufacturing Operations
$150K - $238K *
Shape the future of digital manufacturing by leading strategic IT and operations initiatives. Drive multi-site transformation, ensuring seamless integration of technology and processes to enhance effi...
1 week ago
Senior Director, Order-to-Cash (O2C)
$155K - $160K *
Drive the Order-to-Cash strategy, overseeing cash application, collections, and AR performance. Collaborate cross-functionally to optimize cash flow and enhance financial reporting, ensuring timely re...
1 week ago
Nurse Navigator - South Providence Pediatrics
$75K - $109K *
Champion coordinated care across disease processes, ensuring timely access and quality management. Serve as a resource for patients and healthcare teams, driving best practices and improving outcomes...
1 week ago
Associate Account Executive (St. Louis)
$75K - $95K *
Discover new business opportunities by leveraging relationships and executing consultative sales strategies. Collaborate with cross-functional teams to drive growth and enhance client engagement in a...
1 week ago
$156K - $220K *
Unlock your potential by leading the paid media strategy in a transformative role involving creative innovation and team development, driving growth through data-driven decisions across multiple chann...
Reposted 1 week ago
$65K - $116K *
Drive exceptional client experiences by leading delivery operations, managing relationships, and leveraging analytics to identify service gaps. Collaborate cross-functionally to ensure seamless execut...
1 week ago
$86K - $106K *
Drive advertiser growth by optimizing campaign performance and building strong client relationships. Collaborate with internal teams to enhance product offerings and ensure a seamless advertiser exper...
Reposted 1 week ago
Government Affairs Manager II, Midwest and Central Region
$159K - $168K *
Discover impactful opportunities by leading state and local government affairs in the Midwest, advocating for public policies that enhance community engagement and support the growth of a leading e-co...
Reposted 1 week ago
$91K - $118K *
Accelerate your career by driving technical solutions and proposals for engineered equipment. Collaborate with sales and engineering teams to ensure customer satisfaction and secure new business oppor...
1 week ago
Identity and Access Management Manager
$87K - $293K *
Tackle complex identity governance challenges by leading IGA implementations, guiding teams, and ensuring project success. Leverage your expertise to design solutions, manage client relationships, and...
1 week ago
Identity and Access Management Consultant
$70K - $205K *
Join a team that's dedicated to enhancing identity security solutions. Leverage your expertise in IGA to implement and configure systems, solve client challenges, and collaborate effectively to delive...
1 week ago
Staff Engineer, Cloud Security
$193K - $309K *
Join a dynamic team to enhance cloud security capabilities, leading hands-on initiatives and shaping strategic direction. Collaborate across engineering teams to secure AWS environments and mentor pee...
Reposted 1 week ago
Staff Software Engineer, Orders
$193K - $309K *
Empower the development of innovative features on a high-traffic Orders platform, collaborating across teams to enhance architecture and tooling, ensuring efficient processing for over 1 billion order...
Reposted 1 week ago
$75K - $93K *
Join us to develop and deliver impactful training programs that enhance customer engagement and retention. Collaborate with leaders to identify performance gaps and create solutions that drive measura...
1 week ago
Manager - Software Engineering
$108K - $130K *
Champion innovative software solutions by leading a dynamic engineering team. Collaborate with cross-functional partners to enhance product delivery and drive continuous improvement in a creative, Agi...
1 week ago
Director of Analytics, Revenue Growth
$135K - $160K *
Lead data-driven strategies to enhance revenue growth across customer acquisition, retention, and expansion. Collaborate with cross-functional teams to establish integrated metrics and actionable insi...
1 week ago
$225K - $265K *
Shape the future of oncology by leading clinical studies in early-phase development. Collaborate with multidisciplinary teams to drive innovative therapies and ensure high-quality execution of clinica...
Reposted 1 week ago
Director Fleet Maintenance and Systems Optimization
$120K - $145K *
Lead the charge in optimizing fleet maintenance operations through strategic planning, data governance, and innovative automation. Drive results by enhancing system integration and building strong par...
1 week ago
Project Manager - Commissioning
$120K - $170K *
Optimize project success by leading comprehensive commissioning efforts across critical facilities, managing all phases from planning to turnover, ensuring compliance, quality, and client satisfaction...
Reposted 1 week ago
$100K - $120K *
Transform payment strategies by analyzing interchange and routing data to optimize costs and enhance performance. Leverage advanced analytics and automation to deliver actionable insights for stakehol...
1 week ago
New Grad - Onsite Project Manager
$79K - $116K *
Optimize project delivery by supporting large-scale warehouse automation deployments. Engage with cross-functional teams to track deliverables, manage risks, and maintain schedules, ensuring successfu...
Reposted 1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.