Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Senior Data Center Commissioning Engineer
$130K - $171K *
Lead the charge in building and executing a comprehensive commissioning program for Modular Data Centers, ensuring optimal performance from factory testing to operational handover while collaborating...
1 week ago
Product Manager III - Medicare Advantage
$78K - $118K *
Join a team that's dedicated to enhancing Medicare Advantage products. You'll lead material reviews, ensure compliance, support operational readiness, and conduct competitor analysis to drive strategi...
1 week ago
$150K - $180K *
Drive strategic initiatives and operational excellence by partnering with leadership to translate priorities into actionable plans, fostering alignment, and enhancing decision-making across U.S. & Can...
Reposted 1 week ago
Business Development Representative - USMC
$120K - $140K *
Develop and execute strategic business initiatives, cultivating partnerships and driving revenue growth through market analysis and relationship management. Collaborate with cross-functional teams to...
1 week ago
$193K - $309K *
Lead the charge in delivering impactful GTM solutions by managing a skilled engineering team, overseeing technical operations, and fostering collaboration with stakeholders to drive innovation and qua...
1 week ago
Data Scientist, Enterprise Analytics
$86K - $176K *
Unlock potential by leveraging data science to drive strategic insights and performance across sales and finance. Collaborate with teams to enhance decision-making through advanced analytics, machine...
1 week ago
$160K - $200K *
Pioneer capital relationships across M&A and investment vehicles. Drive fundraising efforts and educate investors on private markets. Build a wealth channel from the ground up while collaborating with...
1 week ago
$70K - $97K *
Elevate your career by driving sales and fostering customer relationships in a dynamic environment. Collaborate with cross-functional teams to introduce innovative products and achieve long-term growt...
1 week ago
Senior Security Engineer, Proactive Security - Platform
$159K - $235K *
Optimize security infrastructure by designing and implementing robust access management and secrets storage solutions, ensuring seamless integration and operational excellence across engineering teams...
1 week ago
Account Executive - Lending Partnerships
$122K - $169K *
Transform the future of home equity lending by driving partnerships with mortgage banks and brokers. Leverage your sales expertise to expand our TPO business, enhance brand presence, and collaborate w...
1 week ago
$88K - $105K *
Help us build lasting customer relationships by diagnosing needs and advocating for solutions. Leverage your expertise in a dynamic environment to drive product adoption and contribute to strategic re...
1 week ago
Senior Advanced Planner (Core Automation)
$84K - $124K *
Optimize advanced material planning activities across customer projects, ensuring procurement readiness and risk identification while facilitating seamless transitions from planning to purchasing exec...
1 week ago
$250K - $300K *
Advance your career by providing exceptional oral surgery care in a supportive, tech-driven practice. Collaborate with a skilled team and enjoy a strong referral base, modern facilities, and ample opp...
Reposted 1 week ago
Startup Products Strategy & Operations, Product Strategy
$125K - $150K *
Shape product strategy and execution for startup products by leveraging user insights, market analysis, and cross-functional collaboration to drive impactful recommendations and clear roadmaps for fou...
1 week ago
Project Manager - Federal (TS/SCI)
$84K - $142K *
Join a dynamic team to lead project implementations, manage budgets, and drive customer success. Collaborate with cross-functional experts to deliver impactful solutions for federal clients, enhancing...
1 week ago
Senior Sales Executive, Strategic Banking
$130K - $160K *
Lead strategic banking initiatives by leveraging your enterprise sales expertise to build relationships and drive new business within Tier 1 global banks, shaping our go-to-market strategy and establi...
1 week ago
Senior Manager, Technology Category Management
$94K - $148K *
Join a team that's redefining technology sourcing strategies to drive savings and innovation. Lead cross-functional collaboration, manage supplier performance, and coach a talented team to optimize te...
1 week ago
Director SMB Digital Growth - B2B Payments
$120K - $145K *
Unlock potential by leading the SMB acquisition lifecycle, driving growth through innovative strategies and digital sales leadership. Collaborate with cross-functional teams to optimize customer engag...
1 week ago
$80K - $95K *
Join a team that's dedicated to optimizing hospital technology systems, ensuring reliable operations and support for clinical and business functions while leading troubleshooting efforts and driving c...
1 week ago
Field Applications Specialist - Core Histology - Kansas City, MO
$90K - $105K *
Champion customer success by providing technical expertise and training in histology applications. Collaborate with sales and service teams to optimize workflows and enhance instrument utilization acr...
1 week ago
Data Center Electrical Engineer - Design
$320K - $405K *
Design and oversee the electrical architecture for cutting-edge data centers, ensuring robust power distribution and integration of advanced technologies. Collaborate with partners to enhance prefabri...
1 week ago
Director of Customer Success, US
$160K - $190K *
Accelerate progress at senior living communities by leading a high-performing Customer Success team, ensuring measurable outcomes and fostering strong partnerships to enhance care delivery and custome...
1 week ago
Director of Psychiatric Clinical Operations
$175K - $210K *
Champion operational excellence in psychiatric care by leading a dynamic team focused on quality, compliance, and innovation. Drive improvements in provider operations and enhance mental healthcare de...
1 week ago
$150K - $180K *
Elevate your career by engaging with clients to design and implement innovative technical solutions. Leverage your expertise in APIs and customer collaboration to drive impactful results in a fast-pac...
1 week ago
$129K - $210K *
Transform issue management by leading a team to develop AI-assisted solutions, ensuring quality and accountability in remediation processes across GRC. Drive engineering excellence while fostering ind...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.