Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Business Development Manager (REQ927)
$95K - $115K *
Pioneer business growth by developing strategic relationships and driving sales initiatives. This role requires effective collaboration across teams to achieve revenue targets and enhance customer sat...
6 days ago
Business Development Manager (REQ927)
$88K - $105K *
Shape the future of business development by driving growth through strategic market engagement, relationship building, and innovative sales strategies. Collaborate across teams to achieve sales object...
6 days ago
$118K - $147K *
Drive successful project delivery by implementing cutting-edge AI/ML solutions on Google Cloud. Collaborate with cross-functional teams to develop strategies, conduct client discovery, and provide tec...
Reposted 6 days ago
$75K - $90K *
Join a dedicated team to provide compassionate, holistic care for hospice patients. Engage in comprehensive assessments, develop care plans, and coordinate with families and healthcare professionals t...
6 days ago
Sr Director Architecture - Train Operations - Remote
$206K - $267K *
Optimize technology investments by providing visionary architecture leadership, aligning enterprise capabilities with corporate goals, and driving strategic initiatives to enhance operational efficien...
6 days ago
$100K - $135K *
Join us to evaluate and underwrite specialty insurance risks, fostering broker relationships and ensuring profitability while maintaining high standards of customer service and operational efficiency...
6 days ago
$132K - $167K *
Lead the charge in strategic talent acquisition for Commercial roles, managing complex searches and guiding senior leaders through the hiring process while leveraging data and innovative tools to enha...
6 days ago
Director of Technology Partnerships
$160K - $240K *
Empower your career by driving technology partnerships, managing relationships, and developing go-to-market strategies. Collaborate with cross-functional teams to enhance integration and achieve mutua...
6 days ago
$120K - $230K *
Engage with major clients to drive AI-led transformation and business solutions. As a key player, you'll develop strategies, build partnerships, and close new opportunities, leveraging your expertise...
6 days ago
$120K - $230K *
Unlock potential by driving new business in the Insurance sector with your sales expertise. Collaborate across teams to develop solutions that address client needs and position the firm as a leader, w...
Reposted 6 days ago
$93K - $125K *
Take ownership of advanced concept evaluations and development efforts. Collaborate with cross-functional teams to architect solutions, lead initiatives, and enhance technology strategies. Drive innov...
Reposted 6 days ago
Global Director of Environmental, Health & Safety (EHS)
$150K - $180K *
Champion global EHS initiatives by developing policies, leading compliance, and fostering a proactive safety culture across diverse operations, ensuring continuous improvement and risk management in a...
6 days ago
Medical Writer, Medical Communications
$80K - $110K *
Transform clinical data into engaging scientific content with growth opportunities. Collaborate, communicate, and adhere to guidelines in a dynamic environment, supporting varied projects across forma...
Reposted 6 days ago
Customer Success Manager, SLED
$80K - $95K *
Champion customer success within SLED organizations. Drive revenue growth by managing relationships, negotiating contracts, and delivering strategic value for an established client base in the public...
Reposted 6 days ago
$90K - $105K *
Grow your career with a transformative digital marketing role focused on optimizing web performance, driving SEO and CRO strategies, and leveraging AI for data insights to enhance user engagement and...
Reposted 6 days ago
Senior Recruiter, Executive & Sales
$100K - $125K *
Champion strategic recruitment initiatives by partnering with executives to build a robust talent pipeline, ensuring alignment with evolving business needs and driving effective sourcing strategies fo...
6 days ago
$125K - $160K *
Take ownership of strategic client relationships, driving retention and growth while leading negotiations and fostering executive partnerships. Collaborate cross-functionally to deliver exceptional cl...
6 days ago
$180K - $190K *
Unlock potential by managing and automating cloud infrastructure, ensuring system security, and optimizing CI/CD pipelines. Collaborate with teams to enhance reliability and performance in a dynamic...
6 days ago
$88K - $105K *
Elevate your career by driving key business objectives and enhancing team performance. Collaborate closely with project leadership to manage hiring processes, support training initiatives, and foster...
6 days ago
Construction Project Manager (grocery store projects)
$80K - $96K *
Innovate with us to lead complex, multi-phase projects, ensuring timely delivery and quality standards. Collaborate with cross-functional teams and external partners to drive project success while man...
6 days ago
Specialty Account Executive ICX - Aerospace & Defense
$146K - $293K *
Drive enterprise sales in Aerospace & Defense, creating strategic opportunities and engaging C-suite executives. Own the full sales cycle, leveraging Siemens' technology to deliver measurable business...
6 days ago
$91K - $121K *
Elevate the commercialization process across the product portfolio, enhancing efficiency and data integrity. Lead cross-functional collaboration, implement automation innovations, and drive strategic...
Reposted 6 days ago
Senior Market Research Analyst - International Development & AI
$70K - $95K *
Join a team that's shaping the future of AI in international development. Lead market research initiatives to identify opportunities, analyze trends, and provide strategic insights that drive business...
6 days ago
$207K - $244K *
Shape the financial data landscape by leading analytics initiatives, ensuring accurate, timely reporting and compliance. Collaborate with cross-functional teams to build scalable data pipelines and ma...
6 days ago
Sr. Customer Development Executive
$171K - $236K *
Drive customer success by managing relationships, identifying upsell opportunities, and collaborating with teams to ensure long-term growth and satisfaction for existing clients, focusing on measurabl...
6 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.