Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$110K - $120K *
Lead the charge in quality engineering for critical assessment platforms, driving testing excellence and automation maturity. Collaborate with cross-functional teams to ensure reliability and scalabil...
Reposted 6 days ago
$108K - $130K *
Elevate strategic analytics by leading a high-performing team to deliver impactful insights, drive business growth, and foster cross-functional collaboration through advanced data modeling and executi...
Reposted 6 days ago
$100K - $120K *
Join a team that's dedicated to delivering exceptional primary eye care while fostering a positive, patient-first culture. Enjoy the freedom to practice your way and grow your expertise in a supportiv...
6 days ago
Senior Human Resources Consultant
$110K - $130K *
Engineer transformative HR strategies as a trusted advisor, partnering with executives to tackle complex workforce challenges and align people initiatives with business goals in a fast-paced environme...
Reposted 6 days ago
$107K - $139K *
Help us lead complex quality improvement projects across multiple sites, integrating quality management systems and enhancing manufacturing processes. Collaborate with cross-functional teams to ensure...
Reposted 6 days ago
$72K - $116K *
Join us in leading our team to achieve excellence in pet care, drive operational success, and enhance customer experiences while fostering a positive culture and community growth in a dynamic retail e...
Reposted 6 days ago
Sr Franchise Business Consultant
$80K - $95K *
Join a team that's dedicated to empowering franchise partners through expert consulting and support. You'll build trusted relationships, drive operational excellence, and help franchisees achieve thei...
6 days ago
$90K - $100K *
Drive new business opportunities and exceed sales targets by building strong customer relationships and executing tailored sales strategies in a dynamic market environment...
6 days ago
Director, AI Vendor Integrations & Standards
$146K - $269K *
Empower innovation by leading vendor AI integration standards, ensuring compliance and interoperability across the enterprise. Drive assessments, manage relationships, and oversee ongoing adherence to...
6 days ago
$80K - $100K *
Join a team that's driving financial insights and pricing strategies to enhance profitability. Collaborate with cross-functional teams to support client proposals and contract renewals while navigatin...
Reposted 6 days ago
Lead Engineer - Mechanical Design Build
$100K - $120K *
Transform the future of engineering by leading innovative mechanical designs for mission-critical facilities. Drive projects from concept to completion, ensuring reliability and efficiency in HVAC and...
Reposted 6 days ago
Senior Engagement Principal | Software Delivery
$212K - $222K *
Champion client success as you lead Aera solution deployments, building trusted relationships with executives to drive value and Decision Intelligence roadmaps while managing project delivery and fost...
Reposted 6 days ago
$84K - $136K *
Transform workplace safety by leading initiatives, training, and compliance efforts. Drive a culture of safety, ensuring adherence to regulations while empowering employees to prioritize health and se...
6 days ago
$104K - $140K *
Help us drive innovation as a Principal Electrical Engineer, specializing in power systems. You will lead design teams, engage with customers, and develop cutting-edge power electronics to meet requir...
Reposted 6 days ago
Senior Process Control Engineer
$96K - $144K *
Champion process automation and digital manufacturing as a Senior Process Control Engineer, driving efficiency and reliability while enhancing organizational capabilities and ensuring sustainable oper...
6 days ago
$150K - $170K *
Elevate employee experiences by leading the design and implementation of integrated HR Service Delivery solutions leveraging ServiceNow and Microsoft technologies...
Reposted 6 days ago
Member of Engineering, Backend - AI
$250K - $250K+*
Pioneer the future of developer AI by architecting scalable backend systems that enhance real-world product experiences through developer-centric cloud infrastructure...
Reposted 6 days ago
Principal, Security Operations
$120K - $145K *
Engage in advanced security operations as a Senior Security Analyst, leading incident response, enhancing detection capabilities, and driving process improvements to protect critical assets in a dynam...
Reposted 6 days ago
$137K - $188K *
Drive innovation in data engineering by leading a dedicated team to develop robust data pipelines, ensuring high-quality data products that empower business decisions and enhance our digital capabilit...
6 days ago
$88K - $105K *
Join a team that's dedicated to driving engineering excellence and innovation. Oversee a skilled group of engineers, manage budgets, and ensure timely project completion while fostering collaboration...
Reposted 6 days ago
$95K - $115K *
Transform data governance by leveraging your technical expertise in Collibra and data quality tools. Drive accuracy and reliability of data assets through hands-on implementation and analysis, ensurin...
6 days ago
Construction Project Manager (bank projects)
$115K - $138K *
Transform project delivery by leading complex, multi-phase initiatives. Oversee cross-functional teams, manage budgets, and ensure timely completion while aligning outcomes with client expectations an...
6 days ago
Floating Licensed Clinical Social Worker - HCPH
$83K *
Transform the lives of youth and families by providing comprehensive clinical assessments, therapy, and case management in a dynamic inpatient and residential treatment environment. Collaborate with a...
6 days ago
Manager Machine Learning Engineering
$185K - $344K *
Lead a dynamic team in developing cutting-edge machine learning infrastructure, driving AI initiatives that impact millions. Foster collaboration and continuous improvement while mentoring talent in a...
Reposted 6 days ago
Forward Deployed Engineer (San Francisco)
$130K - $155K *
Unlock potential by driving innovative AI solutions through hands-on engineering and client collaboration. Transform complex business challenges into reliable, production-ready software while enhancin...
Reposted 6 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.