Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Senior Business Technical Analyst
$87K - $157K *
Lead the charge in transforming healthcare data solutions by leveraging advanced SQL, Snowflake, and SAS expertise. Collaborate with cross-functional teams to enhance business processes and ensure com...
5 days ago
Associate Veterinarian - Small Animal
$90K - $120K *
Transform your career by joining a dynamic veterinary team dedicated to excellence and compassion. Collaborate with experienced professionals as you engage in diverse cases, nurturing both patients an...
Reposted 5 days ago
Sr. Software Engineer, Activations (MANTL)
$132K - $165K *
Transform user experiences by crafting streamlined flows, building robust APIs, and integrating third-party software. Collaborate with a dynamic team to deliver elegant solutions while advocating for...
5 days ago
Staff Software Engineer, Fullstack (Card Experiences)
$204K - $290K *
Lead the charge in creating seamless cardholder experiences by driving technical strategy, collaborating across teams, and fostering a culture of quality and ownership in a dynamic, AI-driven environm...
5 days ago
$135K - $149K *
Analyze and enhance IT infrastructure through secure cloud solutions, ensuring 24x7 availability. Collaborate with teams to streamline workflows, improve system reliability, and tackle complex challen...
5 days ago
Product Sales Manager (ERP-MES) - North America
$95K - $115K *
Elevate sales performance by developing new business opportunities in North America. Drive customer acquisition through tailored MES & ERP solutions while managing the full sales cycle and collaborati...
5 days ago
Sr. Planner, Supply Chain (REQ919)
$80K - $95K *
Optimize supply chain processes by managing inventory, forecasting demand, and ensuring seamless material flow from order to delivery. Collaborate with cross-functional teams to enhance service levels...
Reposted 5 days ago
$185K - $225K *
Champion exceptional member experiences by leading operations, developing talent, and ensuring financial success in a dynamic private club environment. Drive collaboration and accountability while enh...
5 days ago
Senior Associate - Program Management
$95K - $115K *
Deliver impactful project management by co-managing resources, schedules, and risks. Ensure compliance and alignment with strategic goals while utilizing reporting tools to track performance and drive...
5 days ago
$80K - $95K *
Join us to lead talent acquisition and development initiatives, fostering a culture of growth and training. Collaborate with leaders to enhance staffing strategies and build programs that empower empl...
5 days ago
GTM Process & Automation Manager
$101K - $169K *
Optimize North American sales processes and systems to enhance efficiency, drive adoption, and improve outcomes. Collaborate with teams to identify issues, implement solutions, and ensure consistent u...
5 days ago
Admin Director of Nursing - Women's & Procedural Services
$90K - $110K *
Drive operational excellence by coordinating care, managing processes, and fostering innovation. Lead teams to enhance patient safety and quality while addressing system issues and promoting self-deve...
5 days ago
$110K - $220K *
Pioneer innovative sales strategies as you engage with clients, guiding them through the QuotaPath platform. Leverage AI tools to enhance efficiency and influence product development while driving new...
5 days ago
Associate Director, Strategic Program Management
$150K - $195K *
Contribute to the success of IVD and CDx programs by leading cross-functional teams through development, validation, and submission processes. Drive strategic execution and ensure alignment with regul...
5 days ago
Senior Deep Learning Frameworks CUDA Software Engineer
$184K - $356K *
Join a team that's pushing the boundaries of AI technology. As a Deep Learning Engineer, you'll integrate advanced CUDA features and optimize frameworks for high-performance AI applications, tackling...
Reposted 5 days ago
Business Development Representative, Informatics - West
$86K - $173K *
Unlock potential by driving growth in a dynamic sales environment, engaging with diverse stakeholders to close new business and expand existing accounts in the healthcare sector. Embrace a remote role...
5 days ago
Business Analyst, Service Logistics
$95K - $115K *
Drive logistics optimization and cost reduction initiatives across global service operations, enhancing efficiency and performance in transportation and network design while collaborating with cross-f...
5 days ago
Staff Product Manager, Longitudinal Patient Record
$188K - $245K *
Drive the vision for a unified longitudinal patient record, ensuring data accuracy and completeness across multiple sources. Collaborate with cross-functional teams to enhance clinical data utility an...
5 days ago
Research Lead, Open Benchmarks Grants
$135K - $160K *
Transform the future of AI by designing cutting-edge datasets and benchmarks. Collaborate with partners and cross-functional teams to drive impactful research and commercial strategies, enhancing mode...
5 days ago
Oracle Cloud Finance - Director
$155K - $410K *
Innovate the future of finance technology as you lead Oracle Cloud implementations. Drive strategic direction and enhance operational effectiveness while mentoring teams and fostering impactful client...
Reposted 5 days ago
$128K - $160K *
Elevate your coaching career by guiding IT managed service leaders to transform ambition into actionable results. Leverage your experience to foster accountability and drive meaningful progress in a d...
5 days ago
BCS Business Card Consultant - Kansas City
$103K - $127K *
Help us develop profitable business relationships while increasing account revenue. Leverage market insights and strategic sales techniques to identify opportunities and drive growth through consultat...
Reposted 5 days ago
$100K - $120K *
Join a dynamic team as a System Engineer, specializing in Linux systems and automation. You'll lead the design and maintenance of provisioning workflows, configuration management, and Linux networking...
5 days ago
Mid-Level Supplier Quality Engineer - Technical Integration
$100K - $135K *
Analyze supplier capabilities and integrate quality into engineering processes. Contribute to continuous improvement initiatives, ensuring compliance with specifications and regulations while fosterin...
Reposted 5 days ago
$240K - $270K *
Champion advanced analytics to drive strategic insights and business growth. Lead a hands-on team, collaborating with cross-functional partners to enhance product performance, retention, and decision...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.