Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$70K - $117K *
Lead innovative structural engineering solutions for marine vessels, ensuring integrity and compliance with maritime standards. Collaborate with teams to enhance operational safety and performance in...
5 days ago
Power Systems Study Engineer III
$104K - $130K *
Join a team that's shaping the future of power systems for mission-critical facilities. Collaborate on complex projects, conduct in-depth studies, and enhance your expertise in a dynamic remote enviro...
5 days ago
Director - Digital Experience & Strategy (Practice Desktop)
$135K - $160K *
Shape the future of digital experiences for financial advisors, leading a team to enhance practice growth through AI-driven insights and strategic initiatives. Drive cross-functional collaboration and...
5 days ago
Business Development Manager/Account Manager - Air Traffic Control Systems
$193K - $230K *
Contribute to the growth of Air Traffic Control solutions by developing strategic customer relationships, identifying new business opportunities, and managing the sales cycle to enhance market presenc...
5 days ago
$120K - $180K *
Lead integrated campaign strategies that drive measurable pipeline growth across diverse business offerings. Collaborate with marketing teams to translate complex value propositions into clear messagi...
5 days ago
$115K - $125K *
Champion the configuration of our Ascend 2.0 platform by leading spec negotiations and ensuring data quality for client onboarding. Collaborate cross-functionally, manage multiple implementations, and...
Reposted 5 days ago
$160K - $200K *
Join a collaborative team to deliver exceptional orthodontic care in a modern practice. Enjoy clinical autonomy, mentorship, and a supportive environment while maximizing your earnings and achieving w...
5 days ago
Solution Architect, New Logo (Presales)
$150K - $180K *
Join a team that's shaping the future of DevSecOps by guiding customers in building robust processes. Collaborate across departments to deliver tailored solutions and showcase the value of innovative...
Reposted 5 days ago
$163K - $204K *
Partner with us to architect and enhance our next-gen web console, driving frontend infrastructure and user experience across multiple products while ensuring robust security and seamless integration...
5 days ago
Program Manager III, Employee Recognition & Engagement
$87K - $157K *
Champion enterprise employee recognition programs to enhance engagement, oversee design and implementation, manage multiple initiatives, and ensure alignment with organizational goals while fostering...
5 days ago
Forward Deployed Palantir Solutions Lead
$192K - $338K *
Lead transformative AI and data strategies for enterprise accounts, driving value through hands-on engagement and technical leadership. Collaborate with executives to deliver tailored solutions that e...
5 days ago
Senior Manager, Identity & Access Management
$183K - $270K *
Champion IAM initiatives by leading technical implementations and team growth, ensuring seamless access and compliance across global operations while driving automation and user-centric solutions...
5 days ago
$100K - $125K *
Optimize game development by enhancing build systems and automating infrastructure. Collaborate with teams to ensure reliable deployments across multiple platforms, driving efficiency and innovation i...
5 days ago
Project Manager lll - Data Center and Mission Critical
$118K - $147K *
Unlock potential by leading cross-functional teams in mission-critical projects. Oversee deliverables, manage client relationships, and drive strategic business development while ensuring project obje...
5 days ago
Senior Project Manager - Mission Critical and Data Center
$139K - $174K *
Join a team that's shaping the future of mission-critical projects. Lead cross-functional teams, oversee deliverables, and enhance client relationships while managing complex, large-scale projects in...
5 days ago
$95K - $115K *
Optimize your skills as a .NET Developer, focusing on software development, testing, and maintenance. Collaborate with a team to deliver high-quality applications while keeping up with industry standa...
Reposted 5 days ago
Head of Consulting Partnerships
$110K - $130K *
Drive partner success by managing a portfolio of consulting and technology partners, building joint pipelines, and enabling co-selling strategies to achieve revenue goals in a dynamic B2B SaaS environ...
5 days ago
$110K - $130K *
Lead the development of innovative software solutions by mastering .NET technologies, collaborating with cross-functional teams, and delivering high-quality applications that transform client needs in...
Reposted 5 days ago
MISSOURI BAPTIST SULLIVAN HOSPITAL - ANES - STAFF CRNA
$170K - $200K *
Shape the future of anesthesia care in a collaborative environment, focusing on diverse cases with a supportive team. Enjoy a balanced call rotation and the freedom to lead innovative programs while p...
5 days ago
Financial Crimes Intelligence Manager
$98K - $112K *
Analyze financial crime risks by leading a team of investigators and analysts. Oversee complex investigations, enhance monitoring systems, and develop intelligence to mitigate risks while ensuring com...
5 days ago
Financial Crimes Intelligence Manager
$104K - $126K *
Lead the charge in managing a dynamic Financial Crimes Intelligence team, overseeing investigations, enhancing monitoring systems, and developing strategies to mitigate financial crime risks while ens...
5 days ago
Executive Events & Communications Manager
$122K - $155K *
Advance executive visibility and engagement by coordinating high-impact events and communications. Collaborate with senior leadership to enhance corporate reputation and strengthen stakeholder relatio...
5 days ago
$110K - $130K *
Elevate your career by developing innovative Salesforce solutions that enhance customer support and experience. Collaborate with cross-functional teams to design, implement, and optimize integrations...
Reposted 5 days ago
Software Engineer I (Remote Eligible)
$107K - $147K *
Unlock potential by joining a dynamic team to build scalable applications, tackle distributed systems challenges, and leverage AI for smarter development. Collaborate closely with product management a...
5 days ago
$114K - $167K *
Lead the charge in optimizing ERP systems through advanced customizations, integration solutions, and data migration strategies. Collaborate with teams to enhance performance, ensure compliance, and d...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.