Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Jobs in Missouri

Average Salary in USD

Average Salary: $114,671

Sort By: Relevance

$130K - $176K *

Lead complex water resources projects, integrating technical and commercial strategies while guiding multidisciplinary teams through planning, execution, and client engagement to ensure successful del...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$73K - $92K *

Elevate HR compliance by managing policies and processes that align with employment laws. Collaborate with leaders to enhance employee relations and minimize risk while supporting organizational growt...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$91K *

Engage with creators and new media partners to drive impactful campaigns. Oversee operations, manage relationships, and support initiatives that expand outreach and foster collaboration across diverse...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Champion innovation in our remote Engineering team by building and shipping web-based software products. Collaborate with experienced engineers to solve user challenges and enhance our offerings in th...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Transportation

$108K - $130K *

Grow your career with a pivotal role managing strategic accounts in public safety. Drive revenue through upselling and cross-selling, while fostering strong relationships with key decision-makers and...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$130K - $170K *

Drive impactful credit risk analysis across the consumer lending lifecycle, enhancing underwriting strategies and loss mitigation efforts. Collaborate with cross-functional teams to leverage data and...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$115K - $158K *

Join a dynamic team to develop cutting-edge AI for audio experiences. You'll design, train, and optimize machine learning models, collaborating with engineers to enhance product capabilities while pus...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$106K - $195K *

Empower product and engineering teams by delivering actionable insights that shape strategic decisions. As a Senior Decision Scientist, you'll leverage data to influence roadmaps and resource allocati...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Join a team that's redefining report development for public safety platforms. Design and implement dynamic reports leveraging .NET technologies to provide insights that enhance operational decision-ma...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Information Technology

$200K - $400K *

Champion product expansion by launching and scaling non-GLP-1 offerings. Drive growth strategies, analyze market opportunities, and collaborate across teams to ensure successful product launches and r...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$70K - $200K *

Unlock potential by engaging guests through informative tours, converting them into Vacation Club Owners. Drive sales success in a dynamic environment while helping others create unforgettable vacatio...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$130K - $170K *

Champion global payroll operations by managing processes, team leadership, and compliance initiatives across multiple regions, driving strategic improvements to enhance efficiency and accuracy while e...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Staffing

$110K - $130K *

Unlock potential by serving as a top-tier technical expert, mentoring peers, and resolving complex challenges in customer success. Drive scalable processes and enhance team capabilities while engaging...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Unlock new opportunities in industrial feedstock sourcing by building relationships with production companies. Drive methane production through strategic partnerships while ensuring compatibility with...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$168K - $231K *

Lead the charge in shaping legal strategies for enterprise deals, guiding negotiations, and enhancing Optro's contracting processes while collaborating with cross-functional teams to drive success and...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $190K *

Join a dynamic team as you lead financial planning and analysis, driving strategic insights and operational excellence. Collaborate with executives to enhance decision-making and implement innovative...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$90K - $110K *

Join our team to drive sales across innovative solutions, engaging with HR and finance stakeholders. You'll build pipelines, close deals, and shape our market approach for new products, all while coll...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$152K - $203K *

Elevate client partnerships by uncovering growth opportunities and building trusted executive relationships. Drive strategic conversations that connect client needs to innovative solutions, fostering...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Business Services

$110K - $129K *

Advance operational excellence by leading performance management and analytics for mission-critical data center operations. Collaborate with cross-functional teams to enhance service delivery, reliabi...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$140K - $165K *

Lead comprehensive demand generation efforts by managing campaigns, events, and HubSpot systems to enhance pipeline efficiency. Influence strategy and execution for paid media, thereby driving measura...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $150K *

Drive growth by recruiting experienced financial advisors and teams. Collaborate with field leadership to develop strategies, manage pipelines, and enhance market presence, ensuring successful onboard...

RemoteRemote

5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$200K - $250K *

Unlock innovative infrastructure solutions by collaborating with cross-functional teams to design scalable architectures that meet client needs and enhance operational efficiency across data centers...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$88K - $125K *

Unlock potential by leveraging advanced analytics and consultative skills to drive client success in the Consumer Healthcare vitamins sector. Collaborate cross-functionally to deliver insights and fos...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$166K - $200K *

Lead the charge in driving strategic growth through complex transactions, acquisitions, and partnerships. Collaborate with teams to enhance operational efficiency and expand market presence while mana...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $140K *

Elevate your career by designing and managing AWS environments, automating CI/CD, and ensuring robust application delivery. Collaborate with cross-functional teams for end-to-end ownership and enhance...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.