Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Senior Director, BSS Engineering & Product
$240K - $318K *
Lead a global BSS engineering team, driving architecture, delivery, and product strategy while ensuring platform performance and compliance across diverse telecommunications solutions...
Reposted 4 days ago
$125K - $150K *
Drive enterprise sales by building relationships and closing multi-million-dollar contracts. Collaborate with cross-functional teams to deliver tailored IT solutions, ensuring client satisfaction and...
4 days ago
Associate Clinical Territory Manager
$79K - $83K *
Transform healthcare by leveraging your Audiology expertise in a dynamic sales role, demonstrating Cochlear's innovative product offerings while collaborating closely with teams to deliver tailored so...
Reposted 4 days ago
$93K - $155K *
Champion innovative product strategies that enhance the athlete journey, leading cross-functional teams to deliver impactful solutions in the club soccer market while optimizing operational efficienci...
Reposted 4 days ago
Hybrid Sales Representative - South Central
$90K - $93K *
Empower your career by driving sales and customer engagement through hybrid interactions with healthcare professionals. Build relationships, deliver compliant education, and execute strategic plans to...
4 days ago
Hybrid Sales Representative - South Central
$90K - $93K *
Drive sales performance and customer engagement through virtual and in-person interactions with healthcare professionals. Build relationships, deliver compliant education, and execute strategic activi...
4 days ago
Power Generation Electrical Engineer
$90K - $110K *
Drive innovative power generation solutions by leveraging engineering expertise. Collaborate with teams to deliver technical guidance on projects, ensuring compliance with industry standards while fos...
4 days ago
Myna Account Executive, Healthcare and Dental
$100K - $120K *
Join a dynamic sales team to drive AI-powered solutions in healthcare. Engage with decision-makers, uncover challenges, and demonstrate Myna's value to enhance patient access and streamline operations...
4 days ago
$141K - $212K *
Shape the future of AI initiatives by overseeing portfolio management, aligning investments, and ensuring measurable outcomes. Collaborate with senior leaders to drive strategic planning and execution...
4 days ago
$150K - $240K *
Drive the development and deployment of AI solutions, collaborating with customers to enhance workflows and deliver measurable outcomes across various industries. Engage in hands-on engineering from p...
4 days ago
$181K - $290K *
Drive the future of managed marketing by leading strategy, operations, and a high-performing team. Ensure customer success and program scalability while collaborating across functions to deliver excep...
4 days ago
MEP Project Manager - Data Center
$95K - $115K *
Take ownership of MEP project management, ensuring seamless execution of mechanical, electrical, and plumbing systems on complex commercial and industrial projects while collaborating with diverse tea...
Reposted 4 days ago
Director, Strategy & Operations, Consumer
$169K - $298K *
Join a team that's driving growth by identifying key opportunities and leading cross-functional initiatives across Marketing, Product, Sales, and Engineering, ensuring teams execute with clarity to ma...
Reposted 4 days ago
$140K - $200K *
Inspire growth by leading a dynamic machinery team, driving business development, and delivering innovative solutions that enhance client relationships and project success while ensuring high-quality...
4 days ago
$80K - $100K *
Unlock potential by enhancing our sales operations through data management, targeted outreach, and campaign analytics. Collaborate with teams to streamline processes and drive revenue growth with prec...
4 days ago
$155K - $173K *
Join a team that's driving engineering excellence by designing scalable systems, influencing cross-team initiatives, and delivering high-impact solutions while mentoring engineers and upholding high s...
Reposted 4 days ago
Lead Change, Release and Deployment Analyst
$102K - $190K *
Elevate change management processes by leading operational execution and quality assurance. Oversee complex change reviews, coach teams, and ensure compliance with governance standards while enhancing...
4 days ago
Consolidations & Financial Reporting Manager
$84K - $117K *
Empower your career by leading AI-driven automation in financial reporting. Collaborate with teams to enhance efficiency, ensure compliance, and support global consolidation processes while making a s...
Reposted 4 days ago
Remote Behavioral Medical Director, Eastern Region
$215K - $408K *
Support the Chief Medical Director in directing medical management, quality improvement, and credentialing functions, ensuring effective utilization management and enhancing care quality for diverse p...
4 days ago
$107K - $199K *
Pioneer pharmacy services by coordinating medication dispensing, quality assurance, and clinical monitoring. Collaborate with healthcare teams to enhance patient care and ensure compliance with pharma...
4 days ago
Principal Creative Intelligence Analyst
$110K - $120K *
Transform creative performance analysis by owning insights and recommendations for high-stakes accounts. Collaborate across teams to enhance workflows and drive impactful results in a fully remote env...
4 days ago
Senior Director – TV, Audio, and Display Innovation
$170K - $200K *
Lead the charge in transforming TV, Audio, and Display innovation by identifying inefficiencies, advocating for change, and prototyping solutions that enhance client outcomes and differentiate our off...
4 days ago
Affiliate Marketing Senior Strategist, Lead Generation
$100K - $120K *
Drive lead generation success by optimizing performance across diverse verticals. Collaborate with clients and mentor team members to enhance strategies, ensuring compliance and quality while managing...
4 days ago
TV, Video, Audio & Display Strategist
$85K - $100K *
Drive impactful TV, video, audio, and display strategies to enhance customer acquisition and revenue. Collaborate with cross-functional teams to leverage data insights, optimize campaigns, and ensure...
4 days ago
Senior Manager, Insights, Amazon Focus
$105K - $125K *
Join as a hands-on analytics specialist, leveraging Amazon data to drive insights and support decision-making for clients. Collaborate with teams to optimize performance and enhance reporting across v...
4 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.