Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$156K - $239K *
Innovate advanced ArcGIS deployments, collaborating with clients to optimize architecture and integration. Join a dynamic team dedicated to enhancing community impact through cutting-edge web and mobi...
4 days ago
Product Engineer II - Utility Solutions
$79K - $133K *
Drive the design and development of geospatial solutions for utilities, enhancing operations and services across multiple industries, including electric, gas, and telecommunications, while collaborati...
Reposted 4 days ago
Software Development Engineer II- Back End
$97K - $162K *
Elevate your career by building innovative backend services that leverage cutting-edge GIS technologies. Collaborate with a passionate team to create impactful solutions for Defense and Intel clients...
4 days ago
Sr. Partner Manager - System Integrators
$107K - $182K *
Lead the charge in building strategic partnerships with system integrators to drive revenue growth and ArcGIS adoption. Collaborate across teams to enhance partner engagement and execute go-to-market...
4 days ago
Senior System Software Engineer - Dynamo-Triton Inference Server
$224K - $356K *
Transform AI inference by leading the development of advanced GPU-accelerated software, driving feature innovation, and enhancing customer adoption in a collaborative open-source environment...
Reposted 4 days ago
$120K - $234K *
Lead the charge in optimizing SAP Sales and Distribution processes. Collaborate with cross-functional teams to enhance order-to-cash operations while mentoring junior consultants and driving continuou...
Reposted 4 days ago
$94K - $178K *
Elevate application migration success by leading Agile teams through assessments, planning, and execution. Drive collaboration and ensure seamless delivery while managing complex projects aligned with...
Reposted 4 days ago
Enterprise Account Executive, Marketplaces
$135K - $150K *
Drive new business acquisition and revenue growth by proactively selling innovative FinTech solutions to enterprise clients, while managing complex sales cycles and building strategic relationships wi...
Reposted 4 days ago
Oracle Master Data Management Architect
$135K - $160K *
Transform enterprise data management by leading MDM strategies and architectures. Collaborate with stakeholders to ensure data quality and governance while integrating solutions across platforms like...
Reposted 4 days ago
$120K - $145K *
Transform customer data integration strategies by leveraging your expertise to guide clients in optimizing data flow into the Fusion platform, ensuring reliability and value across complex environment...
4 days ago
$120K - $145K *
Join a team that's redefining payroll solutions by leading Oracle Cloud HCM implementations. Collaborate with stakeholders to design scalable, best-practice solutions while mentoring teams and ensurin...
Reposted 4 days ago
$95K - $115K *
Drive successful Oracle project implementations by managing cross-functional teams, ensuring timely delivery within budget, and fostering collaboration in an Agile environment. Utilize strong problem...
Reposted 4 days ago
$120K - $145K *
Advance organizational change initiatives by leading Oracle Cloud transformations. Collaborate with stakeholders to ensure successful adoption through strategic planning, training, and communication...
Reposted 4 days ago
Senior AI Visibility/SEO Strategist
$110K - $130K *
Transform the landscape of enterprise SEO and AI visibility strategies, driving impactful growth for major brands. Lead project execution and client collaboration to enhance discoverability in traditi...
Reposted 4 days ago
$160K - $180K *
Lead the development of AI governance solutions, transforming research into market-ready products. Collaborate with cross-functional teams to ensure customer-focused outcomes and drive product success...
4 days ago
$138K - $203K *
Empower the future of scalable email systems by developing and managing high-performance backend services. Collaborate with cross-functional teams to enhance cloud infrastructure and optimize microser...
4 days ago
Marketing Communications Program Manager
$92K - $138K *
Join a dynamic team as a Communication Manager to enhance media visibility, build strategic relationships, and drive impactful communications in the healthcare sector. Leverage your creativity and exp...
Reposted 4 days ago
Executive Director, Clinical Development
$340K - $370K *
Elevate your career by leading critical clinical programs, ensuring high-quality execution from trial design to regulatory interactions. Collaborate cross-functionally to advance pivotal studies in a...
Reposted 4 days ago
Regional Sales Director - Oklahoma City
$180K - $215K *
Elevate regional sales performance by leading a high-impact team, executing strategic launches, and fostering key customer relationships in a dynamic, fast-paced environment. Drive accountability and...
Reposted 4 days ago
$180K - $215K *
Unlock potential by leading the development of a virtual engagement team to enhance outreach to healthcare professionals, ensuring effective collaboration with field sales and marketing for optimal im...
Reposted 4 days ago
Regional Sales Director - Charlotte
$180K - $215K *
Lead regional sales initiatives, driving product launch success and team performance. Collaborate cross-functionally to execute strategies, foster customer relationships, and ensure compliance while b...
Reposted 4 days ago
SAP Principal Pre-Sales & Delivery Architect
$150K - $180K *
Join us to lead solution direction across multiple SAP engagements, ensuring customer value and platform adoption. Collaborate with teams to shape proposals, drive delivery, and influence product deve...
4 days ago
Sr. Account Executive - Key Accounts
$128K - $150K *
Transform client relationships into growth opportunities as you drive consultative sales cycles for top firms. Collaborate with cross-functional teams to implement strategies, achieve quota, and expan...
Reposted 4 days ago
$95K - $115K *
Champion client success by managing complex engagements in healthcare solutions. Leverage your expertise to enhance Quality/HEDIS, CMS Stars, and Risk Adjustment outcomes, ensuring effective adoption...
4 days ago
Maintenance, Operations and Quality Program Manager
$100K - $155K *
Elevate school facility performance as a Maintenance Subject Matter Expert, optimizing operations through assessments, planning, and training. Collaborate with leaders nationwide to enhance maintenanc...
4 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.