Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Missouri

Average Salary in USD

Average Salary: $114,671

Sort By: Relevance

$105K - $130K *

Unlock potential by leading a dynamic DevOps team to enhance continuous delivery infrastructure, ensuring operational efficiency and security while fostering collaboration and innovation in a fast-pac...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $122K *

Join a team that's dedicated to administering global equity programs while collaborating cross-functionally. Bring your expertise in stock administration and customer service to support equity partici...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$150K - $170K *

Shape the future of car insurance by leading a dynamic actuarial team. Drive innovative pricing strategies, enhance analytical capabilities, and leverage AI to optimize customer experiences while ensu...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$93K - $156K *

Shape the future of advanced Guidance and Control systems for diverse weapons programs. Collaborate on cutting-edge simulations and algorithms, ensuring high-performance solutions that meet customer e...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$150K - $175K *

Lead the charge in integrating acquisitions by developing operational capabilities, ensuring seamless transitions, and driving performance improvements across multiple functions to enhance customer re...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a dynamic team to prepare and review tax compliance across multiple entities, analyze tax laws, and provide strategic insights that drive business growth and decision-making. Your expertise will...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$185K - $250K *

Join a team that's committed to building innovative software solutions that enhance user experience and streamline development processes while collaborating with top-tier engineers to deliver impactfu...

RemoteRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Healthcare

$87K - $109K *

Oversee complex Allied Health claims, utilizing your expertise to analyze, negotiate, and resolve high exposure losses while fostering strong relationships with internal teams and external clients for...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Lead the charge in enhancing technical relationships with healthcare clients, ensuring optimal use of solutions while addressing day-to-day challenges and long-term strategies to support critical clin...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $170K *

Shape the future of network architecture by leading the design of modernized Base Area Networks, ensuring compliance with technical standards and enhancing operational efficiency in a hybrid work envi...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Drive and support deal structuring for a commercial portfolio, collaborating with sales to close strategic opportunities. Manage proposals, objection handling, and internal approvals while enhancing c...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Lead the transformation of senior living operations across multiple communities, driving excellence in occupancy, resident satisfaction, and team engagement while ensuring compliance and financial per...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$140K - $200K *

Lead the charge in optimizing our OpenShift platform, leveraging your DevSecOps expertise to enhance operations and support national security efforts. Collaborate with multidisciplinary teams to craft...

4 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$110K - $130K *

Manage and optimize a unified customer service organization, driving strategy and performance across teams to enhance customer satisfaction, loyalty, and operational excellence while leveraging data-d...

Reposted 4 days ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$99K - $104K *

Shape the future of veterinary toxicology by providing expert consultations to clinics. Collaborate with a dedicated team, manage complex cases, and enjoy a structured schedule that promotes work-life...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$116K - $229K *

Drive ServiceNow HR Service Delivery implementations, optimizing design, build, and deployment. Collaborate with teams to gather requirements, document processes, and ensure project success while enha...

4 days ago

  •   Less than 5 years exp.  •   Business Services

$207K *

Contribute to cutting-edge financial products as a Staff Software Engineer, driving architectural decisions and technical strategy. Collaborate with diverse teams to enhance user experiences while mai...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$105K - $207K *

Unlock potential by enhancing SAP risk management and internal controls. Collaborate with teams to design and implement effective governance strategies, ensuring compliance and operational efficiency...

4 days ago

  •   Less than 5 years exp.  •   Business Services

$116K - $229K *

Deliver impactful ServiceNow HRSD solutions by leading implementations, optimizing processes, and collaborating with cross-functional teams to enhance HR service delivery and client satisfaction...

4 days ago

  •   Less than 5 years exp.  •   Business Services

$105K - $135K *

Champion user engagement by designing and executing lifecycle marketing strategies. Drive retention and conversion through targeted campaigns, leveraging data insights and creative messaging to enhanc...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$184K - $306K *

Grow your career with a dynamic team leading M&A Human Capital strategies, overseeing integration and change management efforts to shape organizational culture, enhance workforce experience, and optim...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Business Services

$105K - $207K *

Join a team that's enhancing SAP risk management and internal controls. Collaborate with clients to design and implement effective governance strategies across ERP transformations, ensuring compliance...

4 days ago

  •   Less than 5 years exp.  •   Business Services

$154K - $265K *

Join a team that's redefining sales enablement by leveraging deep expertise in Governance, Risk, and Compliance. Drive impactful solutions that empower sellers to engage effectively with diverse custo...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$128K - $252K *

Shape AI strategies by conducting stakeholder interviews, prioritizing use cases, and collaborating with teams to develop AI-enabled solutions that drive business value and transformation...

4 days ago

  •   Less than 5 years exp.  •   Business Services

$212K - $344K *

Elevate customer engagement by driving sales growth in the SLED market, leveraging strategic relationships with executive buyers to deliver Workiva's core solutions and optimize value through collabor...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.