Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$90K *
Transform the efficiency of distribution operations by optimizing processes, implementing continuous improvement initiatives, and leveraging advanced technologies to enhance productivity and service l...
Reposted 5 days ago
Physician - Sign on Bonus $75,000
$180K - $220K *
Empower patient care by joining a dynamic team of physicians in a modern, collaborative environment. Deliver high-quality clinical services while enjoying flexible scheduling and competitive compensat...
5 days ago
Strategic Customer Success Manager - Americas
$110K - $130K *
Empower our Enterprise customers by enhancing product adoption and health. Collaborate with cross-functional teams to deliver tailored solutions, ensuring exceptional experiences for high-growth organ...
Reposted 5 days ago
$200K - $240K *
Innovate with us to lead a dynamic marketing organization, driving brand preference and demand generation. Collaborate across teams to align strategies with commercial goals, ensuring impactful campai...
Reposted 5 days ago
Senior Data Scientist I, Monetization
$159K - $188K *
Transform audience and measurement products by independently owning the full lifecycle, from problem framing to delivery. Collaborate with cross-functional teams to enhance data-driven advertising sol...
Reposted 5 days ago
$120K *
Explore opportunities to deepen relationships with hyperscale customers, drive revenue growth, and collaborate with cross-functional teams to deliver exceptional service and support in a fast-paced, r...
Reposted 5 days ago
Senior Director, Offline Marketing
$183K - $322K *
Transform offline marketing strategies to drive growth and efficiency. Own budget, performance, and measurement across channels like TV, radio, and direct mail. Collaborate cross-functionally to optim...
Reposted 5 days ago
Talent Management Partner Lead
$110K - $130K *
Lead the charge in strategic talent management, driving succession planning and critical talent development. Collaborate with HR stakeholders, manage a dedicated team, and implement data-driven strate...
Reposted 5 days ago
Senior/Staff Developer Experience Engineer
$199K - $270K *
Shape the future of software development by enhancing tooling, CI/CD, and operational workflows, ensuring teams can seamlessly transition code changes into production with improved speed, quality, and...
Reposted 5 days ago
Senior Site Safety and Health Officer
$93K - $145K *
Lead safety compliance initiatives and ensure project personnel adhere to health and safety regulations on environmental projects. Collaborate with teams to conduct safety briefings and audits while m...
Reposted 5 days ago
$80K - $95K *
Elevate your career by leading strategic communications across multiple platforms. Collaborate with teams to craft compelling narratives that resonate with diverse audiences while navigating complex r...
5 days ago
Senior Staff Software Engineer - Monetization
$281K - $374K *
Shape the future of monetization platforms by defining technical strategies and building scalable systems. Collaborate with cross-functional teams to deliver impactful solutions in an AI-first environ...
5 days ago
Traveling Project Scheduler, Data Center
$80K - $95K *
Drive successful data center construction scheduling by managing timelines, identifying risks, and coordinating with stakeholders to ensure project delivery meets strict objectives and maintains high...
Reposted 5 days ago
$80K - $95K *
Lead and manage construction projects from inception to completion, ensuring quality and efficiency. Collaborate with teams to deliver exceptional results while navigating challenges and maintaining c...
5 days ago
$100K - $120K *
Transform project management for electronic security installations nationwide, ensuring high quality and compliance while effectively overseeing resources, schedules, and budgets. Collaborate with mul...
Reposted 5 days ago
Managing Consultant - Clinical Quality Improvement - Healthcare
$120K - $165K *
Grow your expertise in hospital quality improvement by leading clinical transformations, analyzing performance metrics, and collaborating with healthcare leaders to enhance patient outcomes and operat...
Reposted 5 days ago
$153K - $170K *
Join our dynamic Legal team as a Senior Counsel, where you'll draft agreements, advise on compliance and privacy, and leverage AI to enhance efficiency. Collaborate with business teams to streamline p...
Reposted 5 days ago
$93K - $134K *
Transform donor engagement by managing relationships, securing gifts, and driving fundraising initiatives. Collaborate with teams to enhance donor stewardship and achieve campaign goals through strate...
Reposted 5 days ago
$88K - $105K *
Engage with us to advance hypersonic weapon systems as a Test Analyst, supporting critical testing operations. Collaborate with engineers and stakeholders to analyze data and develop test plans, ensur...
5 days ago
Hypersonic Aerothermal Test Engineer/Analyst
$95K - $115K *
Unlock potential by leading hypersonic aerothermal test planning and execution, ensuring alignment with government requirements. Collaborate with teams to analyze data and provide expert technical sup...
5 days ago
$101K - $127K *
Advance your career by developing high-quality software solutions alongside cross-functional teams. Implement best practices, optimize performance, and leverage innovative technologies to create scala...
Reposted 5 days ago
$110K - $130K *
Elevate your career by leading integrated marketing programs that drive brand awareness and revenue growth. Collaborate with Sales and executive leadership to translate business goals into impactful m...
5 days ago
$160K - $230K *
Elevate your career by owning the infrastructure and security of a multi-environment platform. Collaborate with leadership to build and operate systems that support critical government operations and...
5 days ago
$80K - $95K *
Manage third-party program relationships, ensuring performance standards and financial accountability while facilitating effective communication between partners and internal teams...
5 days ago
Medical Director/Sr Medical Director (Board Certified Opthalmologist)
$210K - $250K *
Lead the charge in providing medical oversight for clinical studies, ensuring compliance with regulations and delivering expert training. Collaborate with teams to enhance drug safety and therapeutic...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.