Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$81K - $99K *
Partner with us to guide new customers through onboarding, ensuring their success with our platforms. Collaborate with teams to develop strategies that enhance client engagement and support throughout...
5 days ago
$87K - $100K *
Unlock potential by leading complex WAN/LAN network solutions, mentoring IT staff, and driving technology decisions to enhance infrastructure security and reliability while tackling challenging techni...
5 days ago
Client Sales Enterprise Account Executive
$110K - $145K *
Empower enterprise growth by managing high-value accounts in a dynamic SaaS environment. Drive the full sales cycle, build executive relationships, and navigate complex negotiations to achieve impactf...
Reposted 5 days ago
Senior Manager, Deal Desk - North America
$153K *
Shape strategic transactions as the Deal Desk lead for North America, collaborating with Sales and cross-functional teams to enhance deal structure, execution, and compliance while optimizing processe...
Reposted 5 days ago
Forward Deployed Product Engineer (Client Facing)
$180K - $220K *
Join a team that's transforming healthcare by integrating innovative solutions with partners. Collaborate closely with technical teams to deliver seamless integrations and enhance user experiences fro...
5 days ago
$160K - $230K *
Join a team that's redefining product engineering by owning high-impact areas from concept to launch. Collaborate closely with leadership to enhance user experiences and drive innovation in a fast-pac...
5 days ago
Senior Manager, BD - Electronic Warfare
$120K - $145K *
Drive strategic business development initiatives in Electronic Warfare, expanding market presence and fostering relationships with US DoD customers. Leverage expertise to identify opportunities, gener...
5 days ago
$80K - $95K *
Join a dynamic team as a technical liaison, driving innovative solutions and enhancing customer satisfaction through expert application engineering and sales support across diverse industrial systems...
5 days ago
Sr. Design-Build Project Manager
$125K - $150K *
Lead and manage design-build projects, ensuring timely completion within budget while meeting client objectives and contractual obligations. Oversee scope development, financial performance, and compl...
Reposted 5 days ago
$120K - $155K *
Join a team that's dedicated to nurturing and expanding client relationships in the Major Market sector. Drive revenue growth through upselling and cross-selling while ensuring long-term satisfaction...
Reposted 5 days ago
$120K - $150K *
Unlock potential by driving sales strategy and growth in the Southeast. Lead key accounts, identify new business opportunities, and collaborate with teams to deliver exceptional solutions while achiev...
5 days ago
Enterprise Informatics Regional Category Leader - Digital Pathology
$145K - $290K *
Shape the future of Digital Pathology by driving strategic initiatives that enhance customer value and achieve commercial growth across North America, collaborating with cross-functional teams to meet...
5 days ago
$95K - $115K *
Drive IT operations and support in a fast-growing environment, enhancing processes and automating workflows. Collaborate with cross-functional teams to scale IT infrastructure as the company expands f...
5 days ago
Program Manager, Operations Process
$110K - $130K *
Join a dynamic team to enhance operational workflows for autonomous trucking. Lead process design, maintain quality standards, and drive continuous improvement across multiple workstreams while collab...
5 days ago
Solutions Consultant, Commercial
$115K - $159K *
Join a team that's dedicated to driving customer success through tailored financial solutions, utilizing technical expertise and effective collaboration within a fast-paced environment to meet evolvin...
Reposted 5 days ago
Senior Manager, Regulatory Affairs Labeling
$150K - $189K *
Transform global labeling strategies into actionable regional plans, ensuring compliance and quality. Oversee document preparation, vendor management, and cross-functional approvals to deliver timely...
5 days ago
Sr. Software Developer - C#/WPF for UI/UX Development
$123K - $202K *
Join our agile team to design and develop cutting-edge Esri software for raster and imagery workflows in ArcGIS Pro using C#, WPF, and C++. Collaborate to create innovative user interfaces while ensur...
Reposted 5 days ago
Sr. GIS Solution Engineer - AEC
$98K - $173K *
Empower businesses by leveraging GIS technology to solve complex spatial challenges. As a geospatial expert, engage with clients to demonstrate innovative solutions and strategies that drive impactful...
Reposted 5 days ago
Contractor Program Security Officer (CPSO) - TS/SCI
$93K - $158K *
Support critical national security missions by managing program security requirements, collaborating with government customers, and ensuring compliance in classified environments to enable secure miss...
Reposted 5 days ago
$160K - $195K *
Shape the future of payroll and HRIS integrations by ensuring reliability and success. Collaborate with customers and partners to solve technical challenges and enhance the integration experience whil...
Reposted 5 days ago
$72K - $109K *
Execute inventory management strategies to enhance supply chain efficiency, ensuring optimal service levels and minimal spoilage. Collaborate with teams to maintain accurate purchasing and inventory c...
5 days ago
Partner 20, Social Media Lead, Frontier
$199K - $232K *
Unlock potential by driving social media strategy and engagement across diverse platforms. Collaborate with teams to create compelling content, analyze performance, and enhance brand presence while ad...
Reposted 5 days ago
$72K - $109K *
Engage in optimizing inventory management strategies to enhance customer service and minimize spoilage. Collaborate with teams to ensure efficient supply chain operations while achieving key performan...
5 days ago
$120K - $145K *
Pioneer the future of technical content as you drive strategy and execution for Render's content factory, ensuring accuracy and relevance for AI agents and developers. Collaborate closely with teams t...
5 days ago
Staff Product Manager, BioPharma Platforms
$146K - $224K *
Elevate clinical development by leading the strategy for biopharma platforms. Drive product lifecycles, collaborate with cross-functional teams, and ensure compliance while transforming workflows into...
Reposted 5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.