Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$190K - $320K *
Champion the integration of art and technology by leading the animation pipeline, enhancing character rigging and motion solutions, and driving innovation in AI workflows for immersive gaming experien...
3 days ago
Principal Solution Architect, SAP BRIM & Financial Platforms
$152K - $202K *
Champion strategic architecture for SAP BRIM and financial platforms, driving modernization and automation. Collaborate with IT and business stakeholders to establish scalable, secure financial operat...
Reposted 3 days ago
Support Systems Engineer - NAMER
$100K - $120K *
Contribute to the evolution of Support Operations by leading system implementations, optimizing workflows, and enhancing team collaboration. Own the configuration and administration of support systems...
3 days ago
$40K - $150K *
Shape the fitness experience by leading a dedicated team of Personal Trainers while achieving revenue and retention goals. Foster member engagement and uphold standards to ensure successful fitness pr...
Reposted 3 days ago
Senior Manager, Data Engineering
$120K - $145K *
Elevate data engineering by managing pipelines and operations, collaborating with stakeholders to define architecture, and driving project plans for optimal data solutions. Lead teams to ensure data q...
3 days ago
$85K - $158K *
Join a team that's transforming user experiences through innovative digital adoption solutions. Collaborate with stakeholders to design, implement, and enhance in-app guidance, ensuring seamless user...
3 days ago
$202K - $291K *
Lead the charge in strategic program management for the CFO, driving cross-functional initiatives, AI adoption, and operational excellence across Finance and beyond. Shape the future of a fast-growing...
3 days ago
$90K - $175K *
Empower mission success by managing COMSEC lifecycle functions, ensuring the security and integrity of communication systems through expert oversight and compliance with national standards...
Reposted 3 days ago
Senior Analytics Engineer, Clinical Quality and Outcomes
$132K - $145K *
Transform clinical data into actionable insights, bridging stakeholders and data teams to enhance quality, safety, and research analytics. Drive enterprise improvements through innovative data solutio...
3 days ago
$79K - $90K *
Unlock potential by managing procurement and planning processes, ensuring optimal inventory levels, and fostering supplier relationships to meet production demands while driving continuous improvement...
3 days ago
Senior Account Executive, Subscription Sales (Strategics)
$141K - $251K *
Champion enterprise data storage transformation by architecting complex subscription agreements. Collaborate with strategic leaders and engage C-suite executives to drive recurring revenue and redefin...
3 days ago
Applications Engineer - California
$80K - $95K *
Join a team that's dedicated to providing technical support and guidance in membrane systems. Collaborate across departments to optimize solutions, assist customers, and enhance product performance th...
3 days ago
Director, Services Innovation & Special Projects
$170K - $272K *
Lead and innovate within a dynamic team, driving strategic initiatives and managing cross-functional projects to enhance service offerings and achieve business objectives...
3 days ago
Insight Practice Management Implementation Specialist
$80K - $95K *
Transform your career by leading implementation projects in healthcare. Drive successful onboarding and training for Ambulatory Surgery Centers, ensuring optimal system configurations and revenue cycl...
3 days ago
Account Executive | Enterprise | North Central
$110K - $130K *
Join a team that's redefining cloud infrastructure sales. You'll own a vast territory, generate your own leads, and drive new business from initial contact to close, shaping the future of our sales st...
3 days ago
Sr. Program Manager, Superintelligence Lab (Remote)
$125K - $180K *
Lead strategic program management initiatives, ensuring alignment and governance across a complex portfolio while driving results in a dynamic technical environment. Collaborate with cross-functional...
3 days ago
Account Executive | Enterprise | North Central
$110K - $130K *
Drive new business growth by building your own pipeline in a vast territory. Focus on winning new logos through strategic account targeting and disciplined deal management, while collaborating with cr...
3 days ago
$110K - $130K *
Unlock potential by leading new business acquisition and expansion efforts in a dynamic sales environment. Engage key stakeholders to position solutions that drive scalable growth and manage risk effe...
3 days ago
Vice President Sales & Partnerships Insights
$225K - $245K *
Lead the charge in shaping analytics for sales and partnerships, driving insights that enhance revenue strategies. Collaborate with executives to translate data into actionable decisions, fostering a...
Reposted 3 days ago
$160K - $200K *
Empower growth by leading demand generation and marketing operations. Drive strategic campaigns, optimize technology stacks, and manage budgets while ensuring brand governance and team development in...
3 days ago
Account Executive (Texas - Houston)
$80K - $120K *
Join a team that's dedicated to enhancing educational outcomes for English learners. This role involves consultative sales, relationship building, and managing a full-cycle sales process in the K-12 s...
3 days ago
SALES EXECUTIVE (MIDWEST REGION)
$100K - $120K *
Drive profitable growth by expanding customer relationships in food, pharmaceutical, and personal care industries. Collaborate cross-functionally to deliver high-quality ingredient solutions and achie...
3 days ago
SALES EXECUTIVE (MIDWEST REGION)
$100K - $120K *
Engage with key customers in the food, pharmaceutical, and personal care sectors to drive growth through strategic relationship management and business development. Collaborate cross-functionally to d...
3 days ago
Overlay Portfolio Solutions Developer
$108K - $130K *
Drive innovative solutions by applying technical expertise to design and implement seamless overlay management systems that enhance client advisory services, ensuring quality and efficiency across div...
Reposted 3 days ago
$110K - $130K *
Lead the charge in transforming portfolio execution through strategic initiatives, enhancing governance, and driving measurable outcomes across multiple business areas to deliver lasting value and imp...
3 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.