Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Director of Information Technology (IT)
$125K - $150K *
Transform technology strategy across a dynamic manufacturing organization. Lead initiatives in cybersecurity, infrastructure, and digital transformation while aligning IT investments with business goa...
2 days ago
VP, Strategic Growth Executive
$130K - $165K *
Drive strategic growth by acquiring new logos and expanding partnerships within large health systems. Navigate complex sales cycles, build executive relationships, and enhance enterprise value through...
2 days ago
$75K - $95K *
Elevate your career by joining a dedicated team focused on optimizing rehabilitative outcomes for patients with physical impairments in a supportive skilled nursing facility environment...
Reposted 2 days ago
$85K - $100K *
Lead the charge in managing logistics operations, ensuring compliance with DOT regulations while overseeing a team of supervisors and logistics associates to optimize transportation efficiency and saf...
2 days ago
Senior Product Manager - Revenue Management
$110K - $130K *
Transform product strategy and delivery by leading cross-functional teams to enhance Revenue Management solutions, driving innovation and measurable business value in a dynamic environment...
2 days ago
Port Engineer - Tugboat Fleet (Remote with Travel)
$80K - $95K *
Join a team that's dedicated to excellence in marine engineering, supervising vessel maintenance and leading projects to ensure fleet reliability while developing specifications and solutions that enh...
Reposted 2 days ago
$70K - $95K *
Unlock potential by leveraging data insights to drive scalable growth and enhance sales team performance. Collaborate with leadership to develop strategies that improve productivity and operational ef...
Reposted 2 days ago
$100K *
Drive sales growth by engaging clients, providing insurance solutions, and ensuring exceptional service. Leverage your competitive spirit to meet targets while maintaining compliance and documentation...
2 days ago
Senior Business Intelligence Analyst - AI & Automation
$85K - $95K *
Empower your career as a Senior Business Intelligence Analyst, modernizing data extraction and automation. Collaborate across teams to deliver actionable insights using AI and BI tools, ensuring clari...
2 days ago
Lead Clinical Documentation Specialist
$80K - $95K *
Unlock your potential as a Lead Clinical Document Specialist, addressing urgent CDI issues and driving documentation integrity across departments. Collaborate on strategic initiatives, mentor teams, a...
2 days ago
$120K - $145K *
Transform complex security architectures into compelling business narratives that resonate with enterprise decision-makers. Collaborate across teams to drive product positioning, messaging, and go-to...
2 days ago
$106K - $133K *
Champion client success by leading complex upskilling programs, coordinating cross-functional teams, and ensuring seamless delivery of diverse learning solutions tailored to enterprise needs...
Reposted 2 days ago
Director of Financial Planning & Analysis
$140K *
Serve as a strategic financial leader, guiding budgeting, forecasting, and analysis to drive profitability and operational efficiency across the organization. Collaborate with executives to translate...
2 days ago
Supervisory Air Traffic Control Specialist
$100K - $120K *
Grow your career with a leadership role overseeing air traffic control operations. Lead a team of specialists, manage workflow, and enhance operational efficiency while ensuring compliance with safety...
2 days ago
SAP Finance Delivery Lead - Consumer Goods & Services
$163K - $413K *
Champion transformative SAP Finance solutions by leading large-scale projects, engaging with senior executives, and driving innovative strategies that enhance client outcomes and business value across...
2 days ago
$108K - $125K *
Champion innovative solutions as a Full Stack Engineer, delivering impactful features and enhancing systems across projects. Collaborate, design, and optimize applications with a focus on performance...
Reposted 2 days ago
Senior Project Manager, Scrum Master
$130K - $140K *
Lead the charge in delivering enterprise data platform initiatives, managing Agile processes, and ensuring effective collaboration across teams. Drive project execution from discovery to deployment wh...
2 days ago
$122K - $175K *
Unlock potential by leading the design and maintenance of scalable cloud infrastructure. Drive innovation in cloud technologies, ensuring robust security and efficient deployment while collaborating w...
2 days ago
$85K - $100K *
Advance mental health services by leading a dedicated team, ensuring quality care and compliance with VA standards. Provide comprehensive psychological assessments and interventions for veterans, fost...
2 days ago
$175K - $243K *
Engage with enterprise merchants to architect scalable solutions, leveraging technical expertise and collaboration across teams. Drive pre-sale activities, build trust, and influence product developme...
Reposted 2 days ago
Director of Nursing - Psych Acute
$97K - $136K *
Oversee and enhance Behavioral Health programs, ensuring quality patient care and compliance. Lead a dedicated team, develop strategic initiatives, and integrate services to meet diverse patient needs...
2 days ago
Administrative Director of Clinical Operations (ADCO)
$110K - $130K *
Elevate clinical operations by providing strategic leadership and oversight for nursing services, ensuring high-quality, patient-centered care while aligning with organizational goals and regulatory s...
2 days ago
Director, ERP and General Business Systems
$191K - $260K *
Drive ERP strategy and modernization initiatives, collaborating with leaders to ensure technology investments yield significant business value and enhance operational efficiency across the organizatio...
2 days ago
$120K - $150K *
Lead the charge in operational oversight of clinical laboratory services, ensuring compliance with regulatory standards while promoting high-quality, cost-effective testing. Collaborate with healthcar...
2 days ago
Partner Account Director - Digital Advertising - (Remote- US)
$92K - $160K *
Engage with local agencies to drive revenue growth through strategic partnerships. Leverage your expertise in digital sales and agency relations to cultivate relationships, exceed sales targets, and r...
2 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.