Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Payment Integrity Strategic Initiatives Lead
$94K - $130K *
Advance your career by tackling complex business challenges using data insights. Collaborate with stakeholders, lead a team, and drive strategic initiatives to enhance organizational performance and d...
2 days ago
Pharmacy Manager - $150,000 Sign On Bonus and Relocation Available
$112K - $135K *
Drive impactful pharmacy consulting services, enhancing patient care through medication management, immunizations, and clinical services. Lead pharmacy operations, optimize workflow, and foster staff...
2 days ago
$104K - $130K *
Empower growth by transforming complex data into actionable insights. Collaborate with senior leaders to build analytical tools and models that drive strategic decisions, while enhancing operational e...
Reposted 2 days ago
$100K - $120K *
Build and foster strong customer relationships while identifying new business opportunities in the power generation market. Prepare proposals, negotiate contracts, and ensure sales growth through stra...
Reposted 2 days ago
Senior Product Manager, AI Workflow Design| US Remote
$115K - $123K *
Empower users by designing intuitive experiences that simplify complex data and workflows. Collaborate with cross-functional teams to deliver accessible, user-centered designs that align with establis...
2 days ago
Senior Technical Program Manager
$130K - $155K *
Manage complex cybersecurity verification programs across large-scale data center projects. Lead coordination among diverse teams, ensuring operational readiness and technical integration throughout c...
Reposted 2 days ago
Electrical Engineer/Designer Team Lead - MEP
$95K - $115K *
Manage and lead a team of electrical designers, ensuring high-quality technical drawings and effective collaboration across disciplines. Drive departmental growth and technical expertise while deliver...
Reposted 2 days ago
$110K - $130K *
Elevate your career by designing and developing scalable cloud-native applications. Leverage your expertise in Java, Spring Boot, React, and Node.js to enhance Workforce Management and Customer Experi...
2 days ago
$116K - $135K *
Lead the charge in enhancing product security for critical defense systems, ensuring compliance with government regulations while managing risks and implementing robust cybersecurity measures througho...
Reposted 2 days ago
Senior Market Strategy & Optimization Consultant
$110K - $176K *
Unlock potential by driving strategic growth initiatives through competitive intelligence and market insights. Collaborate with cross-functional teams to enhance sales effectiveness and client retenti...
2 days ago
Manager of Payer Revenue Medicare
$80K - $95K *
Unlock potential by leading Medicare billing and coding operations, managing denials, and optimizing revenue cycle performance while ensuring compliance with federal standards...
2 days ago
Remote Board Certified Behavior Analyst (BCBA)
$85K - $105K *
Lead the charge in delivering high-quality ABA services, conducting assessments, and developing treatment plans while mentoring RBTs and collaborating with families to ensure effective client care and...
2 days ago
Remote Board Certified Behavior Analyst (BCBA)
$85K - $105K *
Join a team that's dedicated to delivering high-quality ABA services while fostering clinical excellence and collaboration. You'll lead treatment plans, supervise RBTs, and engage with families to enh...
2 days ago
Director Accounts Receivable Management
$110K - $130K *
Empower revenue recovery by leading payer collections and optimizing strategies for aged accounts. Drive team performance through standardized protocols and proactive monitoring to enhance cash flow a...
2 days ago
Labor Management Program Manager
$80K - $95K *
Advance program management by overseeing lifecycle processes, aligning strategies with leadership, and fostering stakeholder relationships to drive operational excellence and achieve enterprise goals...
2 days ago
Supervisory Agricultural Economist
$110K - $130K *
Lead the charge in agricultural economic research, managing complex projects and analyses on food prices and expenditures. Engage with key stakeholders to disseminate findings and represent the branch...
2 days ago
$140K - $160K *
Drive sales growth by engaging with decision-makers in government agencies. Build relationships, identify opportunities, and collaborate with teams to deliver Investigative Intelligence solutions acro...
2 days ago
SAP Data Migration Senior Manager - Retail
$132K - $302K *
Transform enterprise data migration strategies for S/4HANA, leading complex implementations and mentoring teams. Engage with stakeholders to ensure data quality and governance while driving successful...
2 days ago
$74K - $102K *
Join a team that enhances engineering data management by driving data integrity and system improvements across Engineering, IT, and Business units, ensuring operational excellence and supporting trans...
Reposted 2 days ago
Regional Sales Director- Southeastern US Region
$120K - $160K *
Transform regional sales dynamics by leading an energetic team in the Southeast US, focusing on driving sales initiatives, coaching representatives, and enhancing brand visibility across various HVAC...
Reposted 2 days ago
$110K - $145K *
Drive impactful SAP training initiatives, ensuring end-users are equipped with essential skills for effective SAP S/4HANA utilization. Lead the development and execution of training strategies aligned...
2 days ago
$66K - $115K *
Design and develop innovative security systems using CAD software. Collaborate with engineers to create precise models and drawings that meet technical and regulatory standards, ensuring practical imp...
2 days ago
Facilities Services Manager - Academic Campuses
$88K - $105K *
Lead your career by overseeing facility operations and construction projects across a large academic campus. Foster teamwork and professional growth while managing high-performing teams to ensure oper...
2 days ago
Transmission Line Project Engineer (Central) - Remote
$100K - $166K *
Elevate your career by leading high-voltage transmission line projects. Collaborate with multidisciplinary teams to deliver innovative engineering solutions while ensuring quality and safety standards...
2 days ago
Information Technology Specialist (Information Security)
$85K - $102K *
Lead the charge in enhancing cybersecurity operations by conducting risk assessments, coordinating incident responses, and developing policies to safeguard data integrity and support international tra...
2 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.