Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,967
$135K - $160K *
Transform healthcare technology by owning core products, driving architectural decisions, and ensuring high-quality code. Collaborate across teams to deliver impactful solutions that enhance patient c...
4 days ago
$63K - $111K *
Transform your career by joining a dynamic team as a Security Technician, where you'll travel to install, troubleshoot, and maintain advanced electronic systems, ensuring operational excellence across...
4 days ago
$88K - $115K *
Unlock potential by leading the renewals process, collaborating with cross-functional teams to enhance customer relationships and drive strategic growth opportunities for long-term success...
4 days ago
Procurement Specialist OR Senior Procurement Specialist
$80K - $95K *
Drive procurement excellence by managing supplier relationships and optimizing processes. Take ownership of sourcing strategies, ensuring compliance and cost savings while mentoring team members in a...
4 days ago
Tax & Accounting Practice Lead
$125K - $150K *
Empower healthcare practices by serving as a strategic advisor, enhancing financial performance and operational strategies. Lead client relationships and support growth initiatives in a dynamic, entre...
4 days ago
ServiceNow Mid-Level Developer
$130K - $150K *
Lead the charge in designing and implementing HR Service Delivery solutions, integrating Microsoft 365 with ServiceNow. Optimize employee experiences through automated workflows and seamless connectio...
4 days ago
Staff Software Engineer, Backend (Observability)
$230K - $290K *
Drive the architecture and strategy for a high-volume telemetry platform, mentoring a team while collaborating across functions to enhance observability practices and ensure system reliability at scal...
4 days ago
Mid-Market Account Executive - Public Sector (Southwest)
$152K - $190K *
Join a team that's transforming industries through IoT solutions, driving impactful sales from prospecting to closing. Engage with executives, build lasting relationships, and thrive in a high-perform...
Reposted 4 days ago
$150K - $180K *
Lead the charge in enhancing engineering security for our SaaS platform. Collaborate with teams to identify risks, improve practices, and implement automation, ensuring secure development and robust v...
4 days ago
$144K - $209K *
Drive innovation by building scalable software solutions in a dynamic environment. Collaborate across teams to enhance user experiences and tackle complex challenges while leveraging cutting-edge tech...
4 days ago
Director, Field Reimbursement (FRM)
$210K - $250K *
Empower a dynamic team of reimbursement professionals to enhance provider access and education. Drive strategic initiatives, foster collaboration, and ensure compliance while navigating complex payer...
4 days ago
Health Policy and Government Relations Partner
$110K - $130K *
Lead the development and implementation of health policy initiatives that align with organizational goals. Collaborate with stakeholders to influence policy decisions and improve health outcomes at lo...
4 days ago
$105K - $120K *
Help us drive sales growth and enhance community partnerships by leading a dynamic sales team focused on expanding market share and improving patient registrations in the healthcare sector...
4 days ago
Territory Manager, Inland Marine (P&C Insurance / Inland Marine - Senior Production Underwriter)
$104K - $194K *
Transform your career by spearheading agency relationships and driving profitable Inland Marine solutions while managing a territory remotely, influencing business growth through strategic underwritin...
Reposted 4 days ago
Principal Software Engineer - Marketing Technology
$155K - $197K *
Innovate as a Tech Lead, driving architectural evolution and engineering execution for a global web platform. Collaborate with cross-functional teams to enhance digital experiences through advanced AI...
4 days ago
$160K - $190K *
Unlock your potential as a key player in software development, leading projects from design to deployment. Collaborate with cross-functional teams to enhance applications, optimize performance, and dr...
4 days ago
Principal Product Quality Leader
$138K - $187K *
Lead cross-functional quality initiatives to enhance product health and compliance. Collaborate with diverse teams on regulatory submissions, quality assessments, and process improvements for late-sta...
4 days ago
Copy of Sr Product Marketing Manager, Platform
$130K - $155K *
Join a team that's redefining product marketing by crafting compelling narratives and lifecycle campaigns that drive customer engagement and platform adoption across diverse segments. Collaborate with...
4 days ago
$175K *
Champion enrollment growth by leading a high-performing team, optimizing processes, and enhancing the student experience. Collaborate cross-functionally to drive strategic initiatives and achieve meas...
4 days ago
Senior Application Security Engineer
$125K - $150K *
Join a dynamic team to enhance application security across web apps, APIs, and cloud services. Collaborate with development squads to prioritize vulnerabilities and implement proactive remediation str...
4 days ago
Senior Customer Success Manager, Health Plans
$115K - $181K *
Manage and grow a diverse portfolio of health plan customers, driving satisfaction and retention. Build strategic relationships, navigate complex payor landscapes, and champion clinical outcomes to de...
4 days ago
Director, Proactive Defense Operations
$168K - $281K *
Lead the charge in Proactive Defense Operations, transforming threat data into automated defenses. Drive strategy, team performance, and operational excellence while collaborating across functions to...
4 days ago
$80K - $95K *
Unlock potential by leading compliance audits, ensuring accurate coding and documentation in anesthesia. Collaborate with teams to mitigate risks, deliver training, and maintain regulatory standards w...
4 days ago
$120K - $177K *
Lead and develop a distributed team of Project Coordinators, enhancing operational health and governance across complex automation deployments while driving continuous improvement and collaboration wi...
4 days ago
$100K - $120K *
Advance sales performance by leading a dynamic team, driving revenue growth, and optimizing strategies through collaboration with operations and marketing to achieve business objectives...
4 days ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.