Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,967
$75K - $90K *
Unlock potential by leading accounting services for diverse clients, managing month-end closings, and mentoring junior staff. Utilize your expertise to build client relationships and drive operational...
4 days ago
$94K - $157K *
Shape the future of Salesforce deployments by managing end-to-end release processes. Collaborate with cross-functional teams to ensure high-quality solutions, maintain environment stability, and strea...
4 days ago
$80K - $95K *
Optimize network infrastructure within the DHMS program, ensuring reliability, performance, and security. Collaborate with IT teams to develop policies, troubleshoot issues, and maintain compliance wi...
4 days ago
Key Account Leader, Majors, Public Safety (Northwest)
$144K - $180K *
Transform public safety through strategic account leadership, driving sales for drone technology in major agencies. Own the full sales cycle, build deep relationships, and leverage AI tools to enhance...
4 days ago
$250K - $325K *
Accelerate your career by leading strategic communications and public policy initiatives that shape the future of AI identity and accountability. Drive visibility, influence industry narratives, and b...
4 days ago
VP Business Transformation - Finance
$170K - $200K *
Drive transformative initiatives that enhance business growth and efficiency. Collaborate with senior leaders to identify high-impact opportunities, orchestrate cross-functional teams, and implement i...
4 days ago
Senior Lifecycle Marketing Manager
$110K - $130K *
Transform customer engagement by owning the lifecycle strategy that drives retention and lifetime value. Design multi-channel journeys, leverage data insights, and collaborate cross-functionally to en...
4 days ago
Senior/Staff Full Stack Software Engineer, Frontend Leaning
$135K - $160K *
Elevate user experiences by leading the development of innovative web features. Collaborate with cross-functional teams to deliver high-quality, customer-facing applications using modern technologies...
4 days ago
Business Information Security Officer
$125K - $225K *
Champion cybersecurity initiatives by aligning strategies with business goals, managing risks, and fostering a security-conscious culture. Collaborate with stakeholders to enhance security posture and...
4 days ago
Nurse Manager - Community Care Coordinator
$80K - $95K *
Join a team that's dedicated to enhancing community care for Veterans. Oversee nursing practices, coordinate patient referrals, and collaborate with multidisciplinary teams to ensure high-quality care...
4 days ago
$100K - $120K *
Transform the internal IT landscape by managing employee support, systems administration, and infrastructure scalability. Drive automation and security initiatives while enhancing user experience in a...
4 days ago
$172K - $215K *
Advance your career by leading software development initiatives, driving architecture design, and optimizing performance in a collaborative environment. Engage with cross-functional teams to deliver s...
4 days ago
$103K - $150K *
Champion the implementation process by guiding schools from contract to launch, ensuring efficient setups and strong customer relationships. Drive project success through effective communication and p...
4 days ago
$87K - $123K *
Empower your career by delivering tailored financial planning solutions for large clients. Engage participants through personalized consultations, guiding them in retirement readiness and investment s...
Reposted 4 days ago
$120K - $145K *
Lead the charge in optimizing pharmacy operations and services, ensuring compliance with regulations while enhancing patient care. Collaborate with teams to achieve strategic goals and improve drug th...
4 days ago
Self-Managed Business Development Manager- Central Region
$80K - $95K *
Lead the charge in expanding our commercial fleet market share by identifying and securing new business opportunities. Drive revenue growth through strategic prospecting, relationship building, and co...
4 days ago
$98K - $157K *
Transform product marketing for ERP platforms by crafting compelling messaging and content. Collaborate with cross-functional teams to drive go-to-market strategies and enhance customer engagement thr...
4 days ago
Associate Director, Clinical Solutions Engineering
$177K - $221K *
Drive the development and implementation of innovative clinical solutions, leading a technical team to deliver AI-enabled applications and analytics. Collaborate with stakeholders to ensure scalable...
4 days ago
VP, Sales - Global Client Services
$120K - $140K *
Transform global client relationships by driving revenue growth and strategic account management. Collaborate with C-suite executives to connect workplace culture and employee experience to measurable...
4 days ago
$90K - $110K *
Join a team that's dedicated to empowering customers through technical expertise and support. As a key partner, you'll guide clients in deploying and maximizing our solutions, ensuring they achieve th...
4 days ago
$80K - $95K *
Elevate project outcomes by gathering requirements, improving processes, and providing training. Collaborate with clients and teams to customize solutions and ensure effective system administration wh...
4 days ago
Senior Pre-Sales System Engineer (Albany)
$156K - $234K *
Empower innovation in data storage by collaborating with sales teams to tailor solutions, drive customer success, and showcase technical expertise. Your role will bridge technology and business outcom...
4 days ago
$73K - $102K *
Join a dynamic consulting team as a Senior Developer, leveraging your SAP ABAP-Fiori expertise to design solutions, implement strategies, and drive client success in a rapidly evolving global landscap...
4 days ago
Alliance Marketing Manager, Artificial Intelligence
$126K - $273K *
Shape the future of alliance marketing by architecting innovative demand strategies with strategic tech partners, driving growth and impactful campaigns on a global scale, while collaborating across t...
Reposted 4 days ago
Manager, SEO Marketing (Virtual, US)
$85K - $95K *
Lead the digital strategy for consumer moving, driving SEO initiatives and managing a dynamic team. Shape innovative marketing approaches, optimize online presence, and enhance lead generation across...
4 days ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.