Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,967
Clinical Specialist, Philadelphia
$80K - $95K *
Empower clinical excellence by delivering expert technical support for neurovascular products. Collaborate with healthcare professionals to enhance patient care, drive product adoption, and ensure suc...
4 days ago
General Manager, Healthcare Practices
$275K - $325K *
Drive the growth of healthcare practices by owning strategy, partnerships, and P&L. Collaborate with teams to deliver tailored financial solutions, while leveraging your network to establish Flex as t...
4 days ago
$80K - $90K *
Elevate your career by building and maintaining a network of specialist consultants and physicians. Drive business growth and enhance clinical trial delivery through strong relationships and strategic...
4 days ago
Senior Account Executive - Sports Vertical
$130K - $150K *
Unlock potential by driving new business growth in the sports industry, leveraging your extensive network and sales expertise to close strategic deals and innovate through AI solutions for sports orga...
4 days ago
$69K - $101K *
Manage supplier relationships and procurement processes to ensure seamless production. Collaborate with cross-functional teams to track costs, monitor delivery performance, and resolve material shorta...
4 days ago
Business Development Manager- WA/OR
$95K - $115K *
Accelerate progress at the forefront of commercial fleet sales by driving new customer acquisition and expanding market share through strategic relationship building and consultative selling in a dyna...
4 days ago
Manager, Infrastructure Governance
$125K - $178K *
Accelerate progress at the forefront of cloud security governance, leading a dynamic team to enhance compliance, drive automation, and ensure robust risk management across multi-cloud environments...
4 days ago
Self-Managed Business Development Manager- East Region
$100K - $120K *
Champion growth by driving new customer acquisition and fleet sales within your territory. Leverage consultative selling and relationship-building to secure small to medium-sized business clients, enh...
4 days ago
$150K - $180K *
Transform sales leadership by building and guiding a high-performing team to drive growth and retention in the AMER region, collaborating across departments to execute strategic initiatives and enhanc...
4 days ago
$95K - $115K *
Innovate AI-driven solutions by collaborating with teams to enhance operations, analyze data, and implement advanced analytics across production and office environments, ensuring effective integration...
Reposted 4 days ago
Associate Medical Director, Global Safety Physician
$184K - $253K *
Drive global pharmacovigilance efforts by managing safety data, leading clinical development strategies, and collaborating across teams to enhance product safety and efficacy throughout their lifecycl...
4 days ago
$110K - $130K *
Unlock potential by driving enterprise sales through consultative approaches, managing complex deals with multiple stakeholders, and leveraging a proven sales methodology to achieve targets and foster...
4 days ago
Assistant Vice President - Captive Solutions
$165K - $200K *
Transform captive program management by driving portfolio growth, enhancing underwriting practices, and fostering strong partner relationships. Join a dynamic team to shape innovative solutions and de...
4 days ago
Security & AI Proposal Specialist
$94K - $102K *
Drive your career with a hands-on role coordinating customer security and AI assessments. Collaborate across teams to streamline processes, enhance communication, and ensure timely responses, enabling...
4 days ago
Strategic Accounts Manager, Data Centers - US Robotics West
$110K - $130K *
Join a pioneering team driving sales growth in the data center segment. You'll develop strategies, manage key accounts, and lead a virtual team to enhance customer satisfaction and deliver value in a...
4 days ago
$111K - $167K *
Join a team that's driving healthcare transformation by leading client integration initiatives. Collaborate across departments to ensure seamless transitions, operational readiness, and long-term succ...
4 days ago
$150K - $200K *
Champion the resolution of complex technical issues for clients, leveraging expertise in Linux, networking, and cloud environments. Collaborate with teams to enhance service delivery and operational c...
4 days ago
Post-acute Wound Healing Specialist (Seattle North area)
$104K - $144K *
Unlock potential by serving as a consultative wound care expert, educating clinicians, driving product adoption, and managing accounts to enhance patient healing and business growth in a dynamic healt...
4 days ago
Director, Infrastructure Platform Services
$190K - $316K *
Lead a high-performing platform engineering organization to deliver secure, reliable infrastructure services globally. Drive strategy, execution, and operational management across cloud, AI, and core...
Reposted 4 days ago
Senior Power BI /Dashboard UI Specialist - Remote - USA
$110K - $130K *
Collaborate with clients to design, build, and integrate Power BI solutions, enhancing dashboard UI/UX and driving data insights through effective team engagement and innovative data modeling techniqu...
Reposted 4 days ago
Pharmacist, Home Infusion - Evernorth - Hybrid or Remote
$112K - $189K *
Join us to ensure safe, effective medication therapy while advancing pharmaceutical care. Collaborate with healthcare teams, educate future practitioners, and support drug-related research to optimize...
4 days ago
Product Manager, Provider Marketplace
$120K - $145K *
Join a dynamic team to drive the development of a cutting-edge marketplace, enhancing provider products and economic incentives while collaborating closely with engineering and operations to transform...
4 days ago
Clinical Informatics & Ontology Lead
$120K - $145K *
Lead the design and governance of clinical ontologies and terminology services, ensuring data quality and alignment with product needs. Collaborate cross-functionally to enhance data normalization and...
4 days ago
Director, Business Strategy & Operations, Research
$192K - $288K *
Join a team that's driving strategic initiatives in Neuroscience and Oncology. In this pivotal role, you'll partner with leadership to enhance operations, manage budgets, and streamline workforce plan...
4 days ago
Remote Business Process Consultant (VA ESOM)
$125K - $145K *
Unlock potential by bridging business needs with technical solutions. Collaborate with stakeholders to define requirements, manage product backlogs, and ensure successful delivery of ServiceNow capabi...
4 days ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.