Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,967
Senior Technical Marketing Manager, AI
$120K - $145K *
Unlock potential by driving AI security marketing initiatives, creating demos, and collaborating with cross-functional teams to enhance product visibility and adoption. Serve as the technical voice fo...
3 days ago
Project Manager, Financial Benefits
$98K - $122K *
Empower progress at the intersection of project management and benefits innovation. Lead initiatives for 401(k) MEP and Benefits Billing, collaborating with diverse stakeholders to enhance operational...
3 days ago
Generalist Builder-in-Residence
$100K - $120K *
Shape the future of startups by driving high-impact initiatives across multiple portfolio companies. Engage directly with founders to tackle critical challenges, scale operations, and explore new busi...
3 days ago
Product Manager, Property Intelligence
$95K - $158K *
Transform the Property Intelligence platform by connecting customer needs with product insights. Collaborate across teams to enhance product adoption and engagement through analytics and feedback, dri...
3 days ago
Sr. Site Reliability Engineer (SRE)
$165K - $225K *
Unlock your potential by designing and operating robust Kubernetes infrastructure. Collaborate with cross-functional teams to ensure high-performance, reliable systems that support enterprise-scale AI...
3 days ago
$99K - $164K *
Join a team that's dedicated to enhancing client relationships through strategic management and satisfaction. You'll oversee client communications, identify growth opportunities, and ensure service ex...
3 days ago
Growth Marketing Manager, AI & Paid Programs
$110K - $130K *
Innovate demand generation strategies by managing paid media, automating workflows, and leveraging AI tools. Collaborate with teams to enhance pipeline efficiency and drive measurable results through...
3 days ago
Sr Director of Customer Operations & Delivery
$200K - $230K *
Lead customer success initiatives by managing federal program delivery, ensuring seamless deployment, support, and renewal processes. Drive team performance and build strategic partnerships to enhance...
3 days ago
AI Infrastructure Engineer [Tooling]
$130K - $160K *
Empower AI innovation by designing and building robust tooling for deploying AI agents in production. Collaborate with cross-functional teams to enhance infrastructure reliability and developer experi...
3 days ago
$132K - $170K *
Shape the future of client relationships by driving retention and growth through strategic account management and consultative sales, engaging with C-level executives to maximize value and expand serv...
3 days ago
$150K - $180K *
Shape and execute a comprehensive partnership strategy to drive growth, enhance market presence, and foster high-value alliances across the healthcare ecosystem, collaborating with executive leadershi...
3 days ago
$110K - $130K *
Champion transformative initiatives by translating priorities into actionable plans, coordinating cross-functional teams, and driving organizational change to enhance operational effectiveness and ado...
3 days ago
Lead Test Operations Technician
$107K - $133K *
Champion a skilled team of technicians to optimize test operations, ensuring safety and efficiency at our facility. Lead daily activities, manage workflow, and drive continuous improvement for the suc...
3 days ago
Key Account Leader, Mid Cities East
$110K - $140K *
Lead the charge in driving sales for mid-sized public safety agencies, managing full-cycle deals from opportunity identification to closing. Collaborate with cross-functional teams to ensure successfu...
3 days ago
$106K - $167K *
Join us to analyze and optimize complex business processes, design ERP solutions, and lead integration efforts. Collaborate with teams to enhance performance and ensure compliance while delivering hig...
Reposted 3 days ago
$160K - $190K *
Pioneer innovative AI solutions to transform biomedical discovery, collaborating with top scientists and engineers to bridge virtual and real-world data, enhancing drug discovery and clinical care pro...
3 days ago
Clinical Applications Specialist
$80K - $95K *
Help us deliver exceptional training and support for medical imaging equipment, enhancing customer experiences through expertise and mentorship while traveling frequently to engage with healthcare pro...
3 days ago
$73K - $102K *
Join a team that's transforming ERP solutions by customizing and integrating systems to meet business needs. Collaborate with stakeholders to enhance performance and ensure compliance while delivering...
3 days ago
$110K - $130K *
Drive AI-powered marketing initiatives to optimize campaigns, enhance pipeline generation, and leverage automation. Collaborate cross-functionally while experimenting with emerging technologies to red...
3 days ago
Mission Integration Lead - Survivable Airborne Operations
$130K - $150K *
Unlock potential by leading the design and integration of secure, resilient network architectures for mission-critical systems, ensuring operational performance and recovery objectives are met through...
3 days ago
$80K - $120K *
Shape the future of data-driven decision-making by developing innovative data products and AI solutions. Collaborate with cross-functional teams to deliver impactful analytics and automation tools tha...
3 days ago
Account Executive - Healthcare
$100K - $127K *
Elevate your career by driving new business in healthcare accounts. Engage with C-level executives, navigate complex sales cycles, and close high-value deals to expand market presence and achieve reve...
3 days ago
Territory Sales Manager (IOWA)
$97K - $151K *
Lead the growth of agency relationships to enhance profitability in your territory. Oversee the execution of strategic initiatives, manage agent performance, and deliver training to drive success in G...
3 days ago
$90K - $105K *
Innovate Salesforce solutions to enhance global operations, translating business needs into effective strategies. Collaborate with teams to optimize user experience and drive revenue growth through ad...
3 days ago
$110K - $130K *
Lead the charge in transforming cost estimating processes by developing and implementing advanced methodologies, ensuring accuracy and consistency in estimates while providing technical leadership and...
3 days ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.