Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $110,967

Sort By: Relevance

$120K - $145K *

Unlock potential by driving AI security marketing initiatives, creating demos, and collaborating with cross-functional teams to enhance product visibility and adoption. Serve as the technical voice fo...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$98K - $122K *

Empower progress at the intersection of project management and benefits innovation. Lead initiatives for 401(k) MEP and Benefits Billing, collaborating with diverse stakeholders to enhance operational...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Shape the future of startups by driving high-impact initiatives across multiple portfolio companies. Engage directly with founders to tackle critical challenges, scale operations, and explore new busi...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $158K *

Transform the Property Intelligence platform by connecting customer needs with product insights. Collaborate across teams to enhance product adoption and engagement through analytics and feedback, dri...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$165K - $225K *

Unlock your potential by designing and operating robust Kubernetes infrastructure. Collaborate with cross-functional teams to ensure high-performance, reliable systems that support enterprise-scale AI...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$99K - $164K *

Join a team that's dedicated to enhancing client relationships through strategic management and satisfaction. You'll oversee client communications, identify growth opportunities, and ensure service ex...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Innovate demand generation strategies by managing paid media, automating workflows, and leveraging AI tools. Collaborate with teams to enhance pipeline efficiency and drive measurable results through...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Media

$200K - $230K *

Lead customer success initiatives by managing federal program delivery, ensuring seamless deployment, support, and renewal processes. Drive team performance and build strategic partnerships to enhance...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$130K - $160K *

Empower AI innovation by designing and building robust tooling for deploying AI agents in production. Collaborate with cross-functional teams to enhance infrastructure reliability and developer experi...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$132K - $170K *

Shape the future of client relationships by driving retention and growth through strategic account management and consultative sales, engaging with C-level executives to maximize value and expand serv...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Business Services

$150K - $180K *

Shape and execute a comprehensive partnership strategy to drive growth, enhance market presence, and foster high-value alliances across the healthcare ecosystem, collaborating with executive leadershi...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Champion transformative initiatives by translating priorities into actionable plans, coordinating cross-functional teams, and driving organizational change to enhance operational effectiveness and ado...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$107K - $133K *

Champion a skilled team of technicians to optimize test operations, ensuring safety and efficiency at our facility. Lead daily activities, manage workflow, and drive continuous improvement for the suc...

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$110K - $140K *

Lead the charge in driving sales for mid-sized public safety agencies, managing full-cycle deals from opportunity identification to closing. Collaborate with cross-functional teams to ensure successfu...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$106K - $167K *

Join us to analyze and optimize complex business processes, design ERP solutions, and lead integration efforts. Collaborate with teams to enhance performance and ensure compliance while delivering hig...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$160K - $190K *

Pioneer innovative AI solutions to transform biomedical discovery, collaborating with top scientists and engineers to bridge virtual and real-world data, enhancing drug discovery and clinical care pro...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Help us deliver exceptional training and support for medical imaging equipment, enhancing customer experiences through expertise and mentorship while traveling frequently to engage with healthcare pro...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$73K - $102K *

Join a team that's transforming ERP solutions by customizing and integrating systems to meet business needs. Collaborate with stakeholders to enhance performance and ensure compliance while delivering...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Drive AI-powered marketing initiatives to optimize campaigns, enhance pipeline generation, and leverage automation. Collaborate cross-functionally while experimenting with emerging technologies to red...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$130K - $150K *

Unlock potential by leading the design and integration of secure, resilient network architectures for mission-critical systems, ensuring operational performance and recovery objectives are met through...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $120K *

Shape the future of data-driven decision-making by developing innovative data products and AI solutions. Collaborate with cross-functional teams to deliver impactful analytics and automation tools tha...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$100K - $127K *

Elevate your career by driving new business in healthcare accounts. Engage with C-level executives, navigate complex sales cycles, and close high-value deals to expand market presence and achieve reve...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$97K - $151K *

Lead the growth of agency relationships to enhance profitability in your territory. Oversee the execution of strategic initiatives, manage agent performance, and deliver training to drive success in G...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $105K *

Innovate Salesforce solutions to enhance global operations, translating business needs into effective strategies. Collaborate with teams to optimize user experience and drive revenue growth through ad...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Lead the charge in transforming cost estimating processes by developing and implementing advanced methodologies, ensuring accuracy and consistency in estimates while providing technical leadership and...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.