Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,961
Vice President, Integrated Medicines Business — East
$300K - $500K+*
Join a dynamic team as a senior leader driving portfolio performance across the eastern U.S. Oversee regional execution, manage a team of directors, and collaborate on national strategies to enhance b...
3 days ago
Field Pharmacy Account Manager
$90K - $150K *
Unlock member value by managing pharmacy solutions, optimizing contract use, and fostering relationships with healthcare systems to enhance operational efficiency and savings...
3 days ago
$113K - $188K *
Unlock potential by leading product strategy and management for diverse lines, ensuring customer needs drive innovation while aligning with corporate goals. Collaborate with cross-functional teams to...
3 days ago
Senior Consultant - HHS Collaboratives
$90K - $150K *
Join a dynamic team to leverage clinical expertise in healthcare consulting, driving improvements in perinatal care and women's health. Collaborate with leaders to analyze data, share best practices...
3 days ago
$72K - $120K *
Transform healthcare systems by analyzing data, leading client engagements, and implementing performance improvements. Collaborate with a skilled team to deliver actionable insights and drive meaningf...
3 days ago
Senior Workday Engagement Manager (Certified)
$110K - $130K *
Lead transformative Workday implementations, managing client relationships and project lifecycles. Drive innovation and strategic growth while ensuring exceptional customer satisfaction and effective...
3 days ago
Senior/National Account Director, Market Access
$158K - $250K *
Join a team that's redefining market access strategies in the pharma industry. Leverage your expertise in managed care and payer relationships to drive coverage and reimbursement for innovative therap...
3 days ago
Payment Integrity Program Development Senior Manager
$110K - $150K *
Lead the charge in optimizing payment integrity programs, ensuring effective execution and performance monitoring. Collaborate across functions to drive improvements in operational efficiency and prov...
3 days ago
Director of Clinical Operations, Strategy, and Innovation
$182K - $247K *
Drive innovative clinical operations to enhance member care and outcomes. Collaborate across teams to implement strategies, optimize processes, and scale programs, ensuring seamless coordination and e...
3 days ago
$80K - $95K *
Accelerate your career by leading a dynamic team in sales strategy execution, inventory management, and compliance. Drive growth and enhance customer engagement while ensuring safety and operational e...
3 days ago
Sr. Product Manager, Embedded Payments
$125K - $154K *
Drive the strategy and execution of embedded payments products, collaborating across teams to enhance customer experiences. Leverage data insights to prioritize roadmaps and deliver scalable solutions...
Reposted 3 days ago
$95K - $115K *
Join a team that's enhancing employee separation processes through expert Workday configuration. Leverage your skills in Termination and Offboarding to ensure seamless transitions while collaborating...
3 days ago
Principal Ruby on Rails Engineer
$96K - $207K *
Join a dynamic team to design and implement innovative technology solutions using Agile practices. Collaborate with cross-functional teams to deliver critical products while enhancing your skills in a...
3 days ago
$61K - $104K *
Engage in impactful public health data analysis, utilizing quantitative skills and epidemiological knowledge to enhance surveillance programs and support critical health initiatives...
3 days ago
$78K - $113K *
Innovate healthcare fraud prevention by leading complex investigations, evaluating medical necessity, and collaborating with regulatory agencies to ensure quality member care and safeguard plan assets...
3 days ago
$78K - $113K *
Unlock potential by leading complex investigations into healthcare fraud, waste, and abuse. Collaborate with regulatory agencies and internal teams to ensure compliance and safeguard member care while...
3 days ago
$90K - $189K *
Transform SAP ABAP development for mission-critical DoD logistics systems, ensuring alignment with regulatory requirements and optimizing user interfaces while collaborating across teams to enhance op...
3 days ago
$105K - $231K *
Accelerate progress at the forefront of SAP integration, driving complex data exchanges and ensuring compliance with DoD standards while enhancing transportation operations across diverse systems...
3 days ago
$75K - $158K *
Drive agile excellence by coaching teams in a scaled framework, facilitating planning, and enhancing collaboration. Engage with stakeholders to ensure successful delivery and continuous improvement in...
3 days ago
$90K - $189K *
Shape the future of network infrastructure by leading modernization efforts across classified and unclassified systems. Collaborate with teams to design secure, high-performance networks while ensurin...
3 days ago
$75K - $158K *
Join us to lead agile teams in a dynamic environment, coaching and facilitating processes to enhance productivity and collaboration. Drive successful project delivery while fostering strong relationsh...
3 days ago
$90K - $189K *
Contribute to critical government missions as a Release Train Engineer, facilitating Agile Release Train events, coaching teams, and driving continuous improvement to deliver value using cutting-edge...
3 days ago
Senior Business Systems Analyst
$75K - $158K *
Elevate your career as a Senior Business Systems Analyst, driving modernization initiatives in federal financial systems. Collaborate with teams to analyze data, implement solutions, and lead developm...
3 days ago
Systems SW Analyst / Principal Systems SW Analyst - (UX Designer)
$83K - $125K *
Shape the future of user experience by leading UX design for data analytics products. Collaborate with cross-functional teams to create intuitive interfaces that enhance engineering workflows and driv...
3 days ago
Sr Principal Software Engineer
$129K - $193K *
Lead the development of innovative Data & Analytics solutions, collaborating with cross-functional teams to transform complex data into actionable insights. Drive full stack projects from design to de...
3 days ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.