Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,961
$90K - $137K *
Lead the charge in cloud migration by managing infrastructure engineering tasks, executing migrations to Azure and AWS, and ensuring operational readiness for applications and services in a dynamic, r...
2 days ago
Enterprise Account Executive, Georgia
$300K - $350K *
Drive sales growth in the cybersecurity sector by acquiring new accounts, building relationships, and ensuring customer satisfaction. Leverage your expertise to exceed quotas and manage Channel Partne...
2 days ago
Manufacturing Rotational Program Associate - Chemours Leadership LAB (Early Career)
$73K - $115K *
Launch your engineering career by tackling real manufacturing challenges. Engage in a three-year rotational program that fosters growth through mentorship, diverse experiences, and exposure to industr...
2 days ago
$90K - $110K *
Lead the charge in resolving complex technical issues, enhancing support processes, and collaborating with engineering teams to improve product functionality and customer satisfaction in a dynamic B2B...
2 days ago
Pediatric Online Didactic Faculty
$83K - $95K *
Join a team that's shaping the future of nursing education by teaching innovative online Pediatrics courses. Engage students with cutting-edge methodologies and foster a vibrant online learning cultur...
2 days ago
$98K - $130K *
Drive financial excellence by leading cost accounting operations, ensuring accurate reporting and analysis. Collaborate across departments to support strategic business decisions and contribute to tim...
2 days ago
Director, Global Regulatory Affairs - Cardiometabolic Disorders
$195K - $264K *
Drive global regulatory strategies for obesity and cardiometabolic disorders, ensuring alignment across teams and leading interactions with health authorities. Leverage scientific expertise to navigat...
2 days ago
Asset Lead Medical Director - Obesity and Related Conditions
$217K - $294K *
Innovate the U.S. Cardiovascular & Metabolic Medical strategy, leading evidence generation and stakeholder engagement for chronic weight management. Collaborate cross-functionally to ensure launch rea...
2 days ago
Customer Quality Engineering Specialist
$68K - $109K *
Empower customer satisfaction by representing the Voice of the Customer, resolving cases through data-driven analysis, and coaching teams to enhance quality and prevent non-conformance. Drive cross-fu...
Reposted 2 days ago
$120K - $135K *
Elevate our proposal management efforts by leading strategic submissions, fostering collaboration among teams, and enhancing our pursuit capabilities to secure high-value projects that improve infrast...
Reposted 2 days ago
$150K - $165K *
Transform client relationships by driving revenue growth and satisfaction in healthcare accounts. Collaborate with stakeholders to develop tailored strategies, ensuring long-term partnerships and meas...
2 days ago
Product Manager - Wellness and Social Health
$86K - $138K *
Lead the charge in defining and executing a comprehensive product strategy, driving value across product portfolios. Collaborate with key stakeholders to align strategic vision while overseeing perfor...
Reposted 2 days ago
$134K - $223K *
Lead digital web projects, ensuring optimal performance and compliance across the GSK.com platform. Collaborate with cross-functional teams to enhance user experience, mitigate cybersecurity risks, an...
2 days ago
$120K - $145K *
Lead the charge in delivering complex renewable energy projects, ensuring safety, quality, and budget adherence. Collaborate with diverse stakeholders to drive project success from development through...
2 days ago
Intracept Clinical Specialist - Louisiana / Mississippi
$90K *
Empower surgical teams by providing expert clinical support and training on Intracept devices. This role involves case coverage, technical education, and ensuring compliance, all aimed at enhancing pa...
2 days ago
$90K - $100K *
Join a team that's driving franchise sales success by leading, coaching, and developing a high-performing sales team. Optimize processes, leverage analytics, and collaborate across departments to enha...
2 days ago
$80K - $95K *
Elevate your career as a Senior Accountant, driving day-to-day operations and enhancing internal processes. Collaborate with teams to transition activities, ensuring accuracy and scalability in a fast...
2 days ago
Senior Digital Marketing Manager
$100K - $120K *
Execute multi-channel marketing campaigns, driving results through strategic planning and collaboration. Own project timelines and coordinate teams to enhance player engagement in the crypto and iGami...
2 days ago
Customer Growth & Success Director - Cancer Registry
$135K - $165K *
Drive customer success in Cancer Registry by building relationships, enhancing retention, and translating insights into actionable solutions. Collaborate across teams to improve outcomes and shape bus...
2 days ago
Vice President, Executive Planning Consultant - Washington State & Oregon
$96K - $210K *
Join a team that's dedicated to providing tailored financial strategies for senior executives. As a trusted advisor, you'll enhance client relationships and drive business growth through personalized...
2 days ago
Software Engineer (Time & Billing)
$115K - $120K *
Innovate solutions for time capture and billing in a dynamic team. Leverage AI tools to enhance software development, ensuring accuracy and efficiency in invoicing processes while collaborating across...
2 days ago
$80K - $96K *
Join a team that's driving automation and digital transformation in government and defense. Leverage your RPA expertise to design, develop, and deploy innovative solutions while collaborating with div...
2 days ago
$74K - $91K *
Contribute to national health data collection efforts by leveraging your nursing expertise and survey research skills. Engage in participant-centered data collection, quality control, and training whi...
2 days ago
Direct of Strategic Sales- PR/ Comms/ Media
$119K - $221K *
Advance your career by driving strategic sales initiatives within large enterprises. Collaborate with cross-functional teams to exceed sales quotas and develop innovative solutions that meet client ne...
2 days ago
Founding Account Executive - Travel & Hospitality
$140K - $170K *
Join us to drive growth in the travel loyalty sector by building relationships with airlines, hotels, and gaming operators. You'll lead new business initiatives, shaping partnerships that enhance cust...
2 days ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.