Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,961
Global Marketing Director, Oncology
$195K - $265K *
Transform global marketing strategies in oncology by leading cross-functional teams, driving insights, and optimizing brand value for pipeline assets. Collaborate with stakeholders to enhance commerci...
2 days ago
Manager, BD Electronic Warfare
$110K - $130K *
Unlock potential by driving business development in Electronic Warfare, managing relationships with US DoD customers, and expanding market presence through strategic sales initiatives and customer eng...
2 days ago
Mitigation and Response - Technical
$106K - $214K *
Join a team that's dedicated to enhancing cybersecurity through proactive incident response, threat analysis, and collaboration across various DHS components, ensuring the safety and integrity of nati...
2 days ago
Sales Representative, Pain - Thousand Oaks, CA
$72K - $108K *
Transform your career by developing strategic sales plans and building strong relationships in a dynamic territory. Drive results through effective presentations and ethical practices while achieving...
2 days ago
Sales Representative, Pain - Fresno, CA
$72K - $108K *
Unlock potential by developing strategic business plans and conducting impactful sales presentations. Achieve sales goals while fostering relationships and ensuring compliance with ethical practices i...
2 days ago
$105K - $165K *
Join a team that's dedicated to enhancing AI-driven consumer interactions. You'll analyze AI chat data, identify inaccuracies, and collaborate with cross-functional teams to improve product quality an...
2 days ago
Director, Southeast State Management
$150K - $180K *
Lead the charge in shaping pricing strategy for a key region, overseeing a talented team to drive profitable growth while navigating complex regulatory environments and leveraging data for strategic d...
Reposted 2 days ago
VP, Business Development and Earned Revenue
$172K - $211K *
Drive the development of innovative earned-revenue strategies that enhance mission impact and financial sustainability. Collaborate with cross-functional teams to identify, test, and scale viable busi...
2 days ago
Senior Project Manager, eDiscovery Staffing
$110K - $130K *
Join a team that's dedicated to delivering innovative eDiscovery solutions. Collaborate with cross-functional teams to manage client relationships, oversee project execution, and provide expert guidan...
2 days ago
$80K - $95K *
Champion operational excellence by overseeing regional profitability, managing staffing efficiencies, and driving performance improvements. Collaborate with management to achieve financial goals and e...
2 days ago
Director of Nursing Services Exempt
$80K - $95K *
Transform healthcare by leading nursing teams, managing budgets, and enhancing resident care. Collaborate with stakeholders to implement best practices and foster professional growth in a supportive e...
2 days ago
Director-Business Operations - Student Union
$80K - $95K *
Join a dynamic team to oversee business operations, financial planning, and resource management. Lead and coordinate departmental activities while ensuring compliance and enhancing productivity throug...
2 days ago
$110K - $124K *
Transform the future of AI education by mentoring fellows through their journey, guiding them in technical and organizational challenges while fostering their professional growth across diverse host o...
2 days ago
$130K - $145K *
Champion data privacy across jurisdictions by providing expert advice, managing compliance, and supporting initiatives within a global team. Collaborate with colleagues to ensure lawful handling of pe...
2 days ago
Senior Technical Program Manager
$125K - $150K *
Transform complex customer implementations into seamless successes by owning the delivery lifecycle, driving technical discussions, and ensuring stakeholder satisfaction from kickoff to go-live. Your...
2 days ago
Enterprise Data Analyst Specialist
$102K - $184K *
Join a dynamic team to lead the development of business requirements in Healthcare IT, focusing on data analytics and FHIR standards. Drive innovation and strategy while collaborating with architects...
2 days ago
Director of Public Safety Sales and Business Development
$140K - $160K *
Champion growth in public safety sales by leading a dynamic team, forging strategic partnerships, and driving revenue across North America. Leverage your expertise to enhance market presence and deliv...
2 days ago
Director of Product Operations
$133K - $248K *
Join a transformative team to enhance product operations, driving strategic execution and measurable outcomes. Collaborate across functions to streamline processes, leverage AI, and elevate product ma...
2 days ago
Client Success Manager III - Energy Efficiency
$105K - $120K *
Drive client success by managing utility and energy efficiency programs, ensuring satisfaction, fostering relationships, and identifying growth opportunities while delivering on contractual obligation...
Reposted 2 days ago
$80K - $95K *
Analyze labor market data and audience behaviors to develop actionable insights that enhance recruitment marketing strategies. Collaborate with cross-functional teams to create data-driven audience pe...
2 days ago
Senior Lead GTM Growth Platforms
$105K - $141K *
Contribute to the development of data and tooling capabilities that drive GTM growth strategies. Collaborate across teams to translate business needs into scalable solutions, enhancing marketing and r...
2 days ago
Senior Site Management Associate
$80K - $95K *
Lead the charge in managing site operations and vendor relations, ensuring compliance and efficiency in clinical research projects. Collaborate with teams to streamline processes and enhance training...
2 days ago
$230K - $275K *
Join a team that's redefining B2B sales by leading and mentoring a high-performing regional team while driving significant revenue growth and building a vibrant sales culture in a rapidly scaling envi...
Reposted 2 days ago
Account Implementation Program Consultant
$75K - $95K *
Accelerate client onboarding by leading the implementation lifecycle, ensuring seamless coordination across departments. Drive alignment and maintain operational infrastructure for successful account...
2 days ago
Director of Sales - Eastern US
$150K - $180K *
Drive your career with a leadership role overseeing enterprise sales, guiding a team to exceed quotas while developing strategies that align with market opportunities and fostering strong client relat...
2 days ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.