Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $111,063
New Grad - Onsite Project Manager
$79K - $116K *
Optimize project delivery by supporting large-scale warehouse automation deployments. Engage with cross-functional teams to track deliverables, manage risks, and maintain schedules, ensuring successfu...
Reposted today
Regional Director Plant Operations
$90K - $110K *
Empower facility operations by providing expert maintenance support across multiple centers. Lead training, audits, and contractor management to ensure compliance and enhance operational efficiency in...
Today
Sr Data & Control Systems Engineer
$124K - $186K *
Champion the design and integration of advanced instrumentation and control systems, ensuring safe and reliable operations at a dynamic test facility. Collaborate with cross-functional teams to drive...
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Director, Franchise Operations - South
$145K - $169K *
Transform the South Zone's beverage landscape by driving strategic growth, aligning stakeholders, and executing innovative plans that enhance market performance and profitability across a diverse Coca...
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$232K - $320K *
Unlock potential by leading a dynamic Solutions Consulting team to deliver innovative cybersecurity solutions. Collaborate with sales and customers to ensure value realization and drive success in pre...
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$80K - $95K *
Lead the design and delivery of impactful training programs, creating engaging learning materials and facilitating sessions to enhance employee skills and knowledge across various business units. Driv...
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Senior Information Assurance Analyst / Program Manager
$110K - $130K *
Empower your career by leading the Information Assurance program for critical Army systems. Oversee compliance, manage security processes, and collaborate with stakeholders to ensure robust cybersecur...
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Remote Call Center Triage Registered Nurse
$108K - $155K *
Empower patient care by joining a dedicated team that provides telephonic support, addresses diverse medical and psychological needs, and enhances patient experiences while ensuring documentation accu...
Reposted today
Sr. Architect, AI & Automation
$150K - $190K *
Drive innovation by architecting scalable AI solutions that transform business processes across multiple domains. Collaborate with leaders to establish enterprise standards and governance frameworks f...
Reposted today
$69K - $104K *
Unlock your potential by collaborating with leaders to enhance payor performance, streamline revenue cycle operations, and drive innovation in healthcare. Your expertise will ensure impactful engageme...
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National Accounts Lead Director, Clinical Program Consultant (CPC)
$100K - $231K *
Transform healthcare outcomes by leading a team of Clinical Program Consultants to analyze data, optimize clinical programs, and drive strategic initiatives that enhance customer health and reduce cos...
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Solutions Architect (Pre-Sales & Delivery) - Remote - USA
$125K - $150K *
Drive technical solutions as a client-facing architect, leveraging deep expertise in JavaScript, TypeScript, and Python to guide enterprise-level projects across multiple cloud environments and enhanc...
Reposted today
Projects Procurement Manager USA
$110K - $130K *
Unlock your potential by leading project procurement efforts, optimizing processes, and managing supplier relationships to enhance operational efficiency and profitability across diverse project categ...
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$120K - $160K *
Join a team that's redefining integrated marketing strategies, leading cross-channel campaigns that drive product narratives and customer engagement. Shape the future of marketing through collaboratio...
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$124K - $224K *
Unlock potential by leading revenue operations, bridging sales, finance, and analytics. Drive forecasting, pipeline management, and team development to enhance business performance and ensure data int...
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Let's begin! Director Product Manager- Banking (15734)
$151K - $248K *
Unlock your potential by driving product innovation and cross-functional alignment in a dynamic environment. Lead initiatives that shape lending solutions, enhance decision-making, and deliver impactf...
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(USA) Operations Manager - Floor (fashion, Import, Jewelry, Regional, Returns, Sam's, Wm.com, Hmsc)
$84K - $126K *
Unlock your potential by leading operations in a dynamic environment. Drive performance, enhance quality, and foster team development while ensuring compliance with safety standards and operational go...
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Senior Data Scientist, Marketing Measurement, Consumer Solutions
$115K - $130K *
Drive marketing measurement innovation by developing scalable frameworks and advanced analytics. Collaborate across teams to enhance performance tracking, optimize investment strategies, and deliver a...
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$119K - $180K *
Optimize SAP environments by administering, monitoring, and supporting SAP S/4HANA and related technologies. Collaborate with cross-functional teams to ensure a secure, high-performing system that mee...
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Consultant, Cyber Architecture
$110K - $130K *
Champion your career by leading security engagements, assessing architectures, and enhancing compliance. Collaborate with top professionals to identify risks and implement best practices, ensuring rob...
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$139K - $235K *
Transform compensation strategies by leading program design and execution. Collaborate with cross-functional teams to ensure compliance, enhance processes, and deliver accurate outcomes that attract a...
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Enterprise Account Executive, Ohio
$300K - $350K *
Join a team that's driving sales growth in the cybersecurity sector. This role focuses on acquiring new accounts, building customer relationships, and ensuring satisfaction while exceeding sales quota...
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$90K - $110K *
Join a team that's dedicated to enhancing information security through proactive assessments and innovative solutions. Contribute to compliance and risk management while implementing best practices in...
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Senior AI Engineer with RAG and Agentic architectures
$138K - $165K *
Lead the charge in designing and deploying cutting-edge LLM applications that solve real user challenges. Drive the full AI development lifecycle, ensuring quality and scalability while transforming i...
Reposted today
Revenue Cycle Program Manager (Remote)
$150K - $200K *
Transform revenue cycle operations by leading strategic initiatives, engaging stakeholders, and optimizing financial health through effective project management and collaboration across the organizati...
Today
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.