Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $111,063

Sort By: Relevance

$117K - $161K *

Shape the future of Quality Engineering by leading portfolio management, financial governance, and strategic execution. Collaborate across teams to enhance operational effectiveness and drive transfor...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$106K - $147K *

Drive proactive analysis of the cyber threat landscape, translating insights into actionable strategies for information security. Collaborate with teams to enhance preparedness and countermeasures, le...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Unlock operational excellence by aligning supplier capabilities with business demand. Collaborate across global teams to optimize inventory, enhance supplier partnerships, and drive continuous improve...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Join a dynamic team where your expertise in electrical design transforms concepts into innovative power solutions, impacting real-world projects and driving continuous improvement across a purpose-dri...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Contribute to high voltage service projects by managing coordination between sales, field ops, and customers. Ensure timely execution from installation to invoicing, while supporting reliable grid ope...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Join a team that's dedicated to delivering high-voltage service projects, overseeing the entire process from sales handoff to project execution and customer validation, while utilizing advanced projec...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Drive a culture of safety and excellence as you lead HSSE initiatives, ensuring compliance and fostering continuous improvement. Collaborate with leadership to enhance organizational capability and cr...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Optimize manufacturing processes and lead continuous improvement initiatives, collaborating with cross-functional teams to enhance safety, quality, and performance. Drive data-driven decision making i...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Drive analytics initiatives that connect Paid Media performance to full-funnel outcomes. Collaborate with cross-functional teams to design measurement frameworks, optimize data models, and provide act...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$141K - $234K *

Lead compliance initiatives in privacy, cybersecurity, and digital governance. Collaborate cross-functionally to enhance regulatory frameworks and provide strategic legal guidance to support business...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$141K - $234K *

Shape the future of privacy and AI governance by providing expert legal guidance on compliance with evolving regulations, collaborating cross-functionally to enhance governance programs, and ensuring...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $150K *

Elevate payment integrity operations by leading a team focused on dispute resolution, compliance, and provider education. Drive data analysis and operational excellence to enhance collaborative relati...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join us to drive growth in the Hydraulic Business by leading strategy, fostering customer relationships, and collaborating across teams to deliver innovative solutions and actionable insights that enh...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$90K - $189K *

Manage the design, construction, and maintenance of cloud infrastructure for a federal HCM modernization initiative, ensuring secure, reliable environments and automating deployment processes across m...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $189K *

Lead, shape, and execute advanced penetration testing assessments, overseeing scoping, planning, and reporting. Collaborate with teams to enhance cybersecurity measures across various platforms, ensur...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $189K *

Drive the transformation of federal HR systems by leading the functional design of Oracle Fusion Cloud HCM modules, collaborating with stakeholders to deliver modern, efficient solutions for millions...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $189K *

Join a team that's dedicated to enhancing information technology solutions within the Department of the Air Force. Drive the implementation and modernization of Tenable architecture to ensure complian...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$105K - $231K *

Transform HR solutions by leading Oracle HCM Cloud implementations for federal agencies. Shape functional designs and lead workshops to ensure effective migration from legacy systems in an Agile envir...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$114K - $252K *

Shape the future of cloud infrastructure by optimizing AWS GovCloud environments. Leverage your expertise in architecture and security compliance while empowering technical teams toward innovation and...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $189K *

Join a team that's redefining cyber analysis by designing AI-assisted workflows to enhance cybersecurity. Leverage expertise in Python automation and security to streamline the triage of complex cyber...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $189K *

Elevate your career as you design, implement, and maintain SAP security roles across various platforms while ensuring compliance and optimizing security frameworks in a collaborative environment...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$75K - $158K *

Drive enterprise-level technical solutions by analyzing system needs, coordinating design activities, and ensuring compliance with governance processes. Leverage your expertise to enhance performance...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$75K - $158K *

Join a dynamic team to develop RPA solutions using UiPath and Java technologies. Engage with stakeholders to implement automation solutions that enhance workflows while working on cutting-edge project...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$82K - $172K *

Transform your career by leading the integration of Oracle EBS and Cloud EPM. Spearhead data flow management and architectural redesign while collaborating with technical teams to enhance financial sy...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $189K *

Architect comprehensive testing strategies and oversee automation efforts for a vital supply chain management system. Lead a team to ensure effective test cycles and enhance capabilities, delivering a...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.