Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,961
Senior Infrastructure Engineer
$163K - $224K *
Transform your career by automating and improving infrastructure systems, collaborating with engineering teams, and enhancing operational efficiency as part of a dynamic team focused on self-service s...
Reposted 2 weeks ago
$100K - $140K *
Reimagine client success by managing relationships and ensuring seamless communication across teams. Drive operational excellence and enhance client satisfaction through proactive updates, coordinatio...
2 weeks ago
Staff Software Engineer - ML/AI
$148K - $254K *
Transform connected systems by designing and deploying advanced anomaly detection models. Lead a team to build robust pipelines, ensuring real-time analysis and integration across AI and engineering t...
2 weeks ago
Sales Director, New Business - Financial Services
$175K - $241K *
Empower a high-performing sales team in the Financial Services sector, driving new business growth and fostering long-term client relationships. Lead with a consultative approach to exceed revenue tar...
2 weeks ago
$175K - $190K *
Shape the future of search by designing intuitive, engaging experiences that enhance user interactions and drive revenue. Collaborate with cross-functional teams to create a seamless journey for neigh...
2 weeks ago
$135K - $160K *
Lead the charge in designing cutting-edge infrastructure for large-scale AI deployments. Collaborate with multidisciplinary teams to ensure seamless execution from concept to construction, maintaining...
2 weeks ago
Software Engineer II, Full Stack (Card Acquisition)
$146K - $206K *
Join a team that's driving innovation in card acquisition by leveraging technology and data insights to create seamless user experiences and foster customer loyalty. Collaborate with cross-functional...
2 weeks ago
AI Native Delivery Manager (AI/Run practice)
$120K - $145K *
Grow your career with a dynamic role leading AI Native pods, managing cross-functional teams through education and client engagements, while championing AI SDLC practices and ensuring delivery excelle...
2 weeks ago
Territory Sales Manager - CCST (Midtown Manhattan, NY)
$108K - $135K *
Unlock your potential by driving sales success in specialty biopharmaceuticals. Collaborate with healthcare professionals to enhance patient outcomes and execute strategic business plans within primar...
Reposted 2 weeks ago
Lead Civil Engineer - Renewables
$111K - $150K *
Drive innovative civil engineering solutions for utility-scale solar projects. Lead design teams, mentor engineers, and ensure high-quality project execution while collaborating with clients and stake...
2 weeks ago
$120K - $145K *
Innovate with us as a Senior Software Engineer, driving core feature development and automation across the stack. Collaborate with diverse teams to enhance scalability and performance in a dynamic, mi...
Reposted 2 weeks ago
Senior Vice President, Marketing - Retirement, Investment & Wealth Solutions
$300K - $325K *
Drive your career with a strategic leadership role focused on enhancing marketing initiatives, optimizing client engagement, and achieving commercial growth across diverse financial services sectors...
2 weeks ago
$125K - $150K *
Unlock potential by joining a high-impact team focused on managing global financial crime risks. Collaborate across functions to develop risk-based policies and controls that ensure compliance and sup...
2 weeks ago
$95K - $115K *
Optimize customer success by driving engagement and retention, ensuring clients maximize value from services. Collaborate with teams to enhance the customer experience and advocate for their needs, co...
2 weeks ago
$125K - $150K *
Join our dynamic team as you lead Methods and Insights, driving engineering excellence through effective people management, operational delivery, and innovative system building. Empower engineers to t...
2 weeks ago
$115K *
Transform your career by driving net-new logo sales in the mid-market space. Leverage your HRMS/Payroll expertise to exceed quotas and build lasting client relationships while benefiting from exceptio...
2 weeks ago
Global Vice President, Mid-Market Sales
$200K - $225K *
Accelerate growth by leading a global Mid-Market sales organization, driving strategy and execution across regions. Build a high-performing team, optimize sales processes, and foster partnerships to a...
2 weeks ago
$94K - $99K *
Elevate your culinary career by preparing high-quality meals in large volumes across the nation. Join a dynamic team dedicated to excellence in culinary operations, disaster response, and remote workf...
2 weeks ago
Senior Network Development Contractor
$100K - $120K *
Drive network expansion by engaging providers and negotiating contracts to enhance Medicare services. Collaborate with a remote team to ensure network adequacy and build strong relationships with heal...
2 weeks ago
Program Administration Director
$130K - $216K *
Transform program administration for a large federal services initiative, overseeing workforce planning, financial operations, and compliance. Collaborate with diverse teams to enhance operational eff...
2 weeks ago
Senior Medical Science Liaisons (MSL) - Cardiovascular, Florida
$190K - $225K *
Drive scientific engagement as a Senior Medical Science Liaison, fostering relationships with Key Opinion Leaders and healthcare professionals. Leverage your expertise in cardiovascular disease to sup...
2 weeks ago
$135K - $160K *
Transform client relationships by leading customer success strategies, driving utilization, and maximizing retention across enterprise health systems. Oversee a high-performing team to ensure client s...
2 weeks ago
$150K - $180K *
Join us to lead groundbreaking research in quantum technologies, shaping innovative measurement approaches and collaborating with cross-functional teams to drive product development and experimental v...
2 weeks ago
$166K - $195K *
Shape the future of talent acquisition by leading full-lifecycle recruiting for senior roles. Collaborate with leaders to enhance hiring strategies, build strong candidate pipelines, and drive process...
2 weeks ago
$135K - $160K *
Lead the charge in delivering innovative solutions as a Solutions Architect, guiding teams and customers through technical challenges while maximizing mission impact and enhancing customer experiences...
2 weeks ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.