Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,961
$150K - $180K *
Transform the future of quantum technology by leading product definition and architecture for a groundbreaking initiative. Collaborate with cross-functional teams to shape solutions and drive market e...
2 weeks ago
$80K - $90K *
Lead the visual narrative of client brands by delivering exceptional design solutions across multiple channels. Collaborate with diverse teams to uphold high standards and participate in innovative pr...
Reposted 2 weeks ago
$90K - $110K *
Transform complex clinical data into compelling copy that resonates. Collaborate with cross-functional teams to create impactful healthcare campaigns, ensuring accuracy and brand voice across diverse...
2 weeks ago
Senior Manager, Integrated Intelligence
$85K - $105K *
Shape impactful insights through analytics, driving data-informed decisions for healthcare clients. Collaborate with cross-functional teams to enhance marketing performance and audience understanding...
Reposted 2 weeks ago
Account Director, Promotional Medical Education
$100K - $120K *
Partner with us to drive strategic healthcare marketing initiatives. Lead client relationships, oversee peer-to-peer programs, and mentor team members to ensure compliance and achieve results while fo...
Reposted 2 weeks ago
Marketing Manager (Entertainment & Commercial)
$80K - $95K *
Lead the marketing strategy for our Entertainment and Commercial team, managing projects from conception to execution. Collaborate with cross-functional teams to create impactful sales materials, supp...
2 weeks ago
Business Analytics Engineer, Customer Insights
$100K - $120K *
Lead the charge in transforming healthcare analytics by building robust data models and dashboards. Collaborate with diverse stakeholders to deliver actionable insights, ensuring data quality and clar...
2 weeks ago
$80K - $95K *
Transform the workplace by aligning HR strategies with business goals. Collaborate with leaders to enhance employee engagement, manage complex relations, and drive compliance while supporting multiple...
2 weeks ago
$110K - $130K *
Unlock developer potential by creating engaging content, organizing events, and fostering community connections. Collaborate with cross-functional teams to enhance user experience and advocate for dev...
2 weeks ago
$90K - $100K *
Join a team that's dedicated to driving client success through strategic marketing engagement. You'll manage client relationships, enhance platform adoption, and collaborate cross-functionally to achi...
2 weeks ago
$170K - $195K *
Elevate revenue growth by building strong relationships with law firms and corporations. Drive new business development through consultative sales, leveraging industry insights and collaboration with...
2 weeks ago
Principal Contracts Strategist (Pre-Award)
$125K - $150K *
Lead complex contract strategy and execution, enhancing scalable systems to support sales and growth. Collaborate across teams to align contracts with business needs while addressing immediate challen...
2 weeks ago
$100K - $140K *
Champion the early stages of the sales journey by qualifying leads, conducting discovery calls, and collaborating cross-functionally to enhance customer engagement and drive automation solutions in ma...
2 weeks ago
Director, Sales Engineering (Presales) - Retirement & Pension
$165K - $195K *
Transform enterprise sales and modernization for retirement technology. Lead a team of Sales Engineers, engaging with diverse stakeholders to deliver tailored solutions and drive impactful customer ex...
2 weeks ago
Manager, Network Connectivity & Carrier Strategy
$150K - $200K *
Drive the future of network connectivity by managing site selection, carrier negotiations, and team leadership to ensure robust, efficient data center connections globally. Collaborate with engineerin...
2 weeks ago
Principal Specialist Sales Engineer, Zero Trust Branch - Healthcare/SLED
$175K - $251K *
Lead the charge in transforming customer experiences through innovative cloud security solutions, leveraging your expertise to craft tailored technical presentations and solutions that drive strategic...
Reposted 2 weeks ago
Associate Medical Director (Promotional Medical Education)
$100K - $125K *
Manage a team of medical writers to develop impactful scientific content, ensuring accuracy and compliance. Collaborate with clients and cross-functional teams to drive medical strategies and delivera...
Reposted 2 weeks ago
Operational Technology (OT) Engineer
$76K - $118K *
Explore a pivotal role in enhancing operational technology solutions for Army facilities. Collaborate with diverse teams to ensure system security, reliability, and compliance while supporting moderni...
2 weeks ago
$125K - $150K *
Elevate your career as a Senior Data Engineer, driving innovation in cloud-native data pipelines and architectures. Leverage your expertise in structured credit and financial analytics to modernize da...
2 weeks ago
$182K - $243K *
Lead a dynamic communications team to shape brand narrative and media presence, driving public safety technology's impact through proactive strategy and crisis management across various platforms and...
Reposted 2 weeks ago
$210K - $250K *
Lead global revenue growth by driving B2B sales strategies, managing high-performing teams, and expanding market presence across key sectors. Collaborate cross-functionally to achieve ambitious revenu...
2 weeks ago
Virtual Telehealth Nurse Practitioner
$100K - $120K *
Elevate patient care by delivering virtual health services, ensuring compliance with regulations, and fostering teamwork in a dynamic environment. Utilize your expertise to provide accurate diagnoses...
2 weeks ago
Sr Software Engineer (Backend)
$140K - $165K *
Join a dynamic team as you lead the design and development of complex software systems. Drive technical direction, mentor peers, and ensure high-quality, scalable solutions that align with business go...
2 weeks ago
Senior Director, Software Engineering
$145K - $190K *
Lead the charge in designing and optimizing scalable data pipelines using Azure, PySpark, and Airflow. Collaborate with teams to ensure data quality and performance while mentoring engineers and drivi...
2 weeks ago
Patient Programming / Ambassador Manager
$205K - $228K *
Champion patient-focused initiatives by leading strategy and execution of ambassador programs. Build relationships with patients and advocacy groups to enhance engagement and ensure their voices shape...
2 weeks ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.