Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,961
Client Growth & Success Principal Manager- Enterprise Accounts
$150K - $175K *
Shape the future of client partnerships by driving strategic growth and success for large enterprise organizations. Collaborate with cross-functional teams to deliver exceptional value and measurable...
2 weeks ago
Senior Data Engineer - Data Platform
$130K - $160K *
Champion the migration to a modern Databricks lakehouse, designing robust data pipelines and ensuring data quality. Collaborate with teams to enhance analytics capabilities and set technical standards...
2 weeks ago
$110K - $130K *
Champion strategic growth by managing key accounts, fostering relationships, and driving sales initiatives. Collaborate with leadership to meet customer needs and exceed performance objectives while r...
Reposted 2 weeks ago
$215K - $230K *
Transform compliance into actionable insights by bridging technical teams and auditors. Own your area of responsibility, enhance security measures, and drive automation in a multi-cloud environment wh...
2 weeks ago
$110K - $130K *
Join a team that's redefining organizational strategy and driving impactful solutions. As a Senior People Partner, you'll collaborate with leadership to align talent priorities with business outcomes...
2 weeks ago
Manager, Regional Sales - Specialty (Penn-Erie)
$149K - $187K *
Drive regional sales success by leading a team of Territory Sales Managers, fostering a culture of accountability and collaboration, and executing strategic initiatives to achieve performance targets...
2 weeks ago
Customer Success Engineer - LATAM
$100K - $200K *
Join a team that's dedicated to enhancing customer success through technical expertise. You'll build strong relationships with enterprise clients, guiding them in adopting our products and ensuring th...
Reposted 2 weeks ago
Associate Director, Regulatory Project Management
$136K - $220K *
Unlock project management excellence in Global Regulatory Affairs, driving timelines and compliance for drug submissions. Collaborate cross-functionally to ensure accurate documentation and effective...
Reposted 2 weeks ago
Senior Manager, Clinical Conduct
$90K - $110K *
Empower cross-functional teams to drive the Future of Medicine initiatives, ensuring scalable processes and compliance while enhancing patient safety and experience through strategic planning and exec...
2 weeks ago
Client Growth & Success, Senior Manager- Enterprise Accounts
$130K - $145K *
Champion client success by managing strategic partnerships with mid-sized enterprises. Drive measurable outcomes through relationship management, consultative problem-solving, and cross-functional col...
2 weeks ago
Senior Product Marketing Manager, Core (Remote, US)
$117K - $130K *
Transform your career by leading strategic go-to-market initiatives for a fast-growing ELA Core Curriculum portfolio. Drive impactful messaging, cross-functional alignment, and scalable processes to e...
2 weeks ago
$90K - $110K *
Lead the charge in ensuring compliance and integrity within federal healthcare programs through rigorous investigations, data analysis, and collaboration with key stakeholders to produce actionable fi...
2 weeks ago
$95K - $115K *
Join a dynamic global accounting team as you manage international audits, enhance month-end close processes, and drive improvements in accounting operations. Take ownership of complex projects while c...
2 weeks ago
Continuous Improvement Engineer
$120K - $135K *
Drive operational excellence by leveraging data analysis and Lean Six Sigma methodologies. Lead initiatives that enhance performance across functions, mentor teams, and align improvements with strateg...
2 weeks ago
$150K - $500K *
Accelerate progress at a leading pharmaceutical engagement firm by driving sales strategy and growth for a new compliance-focused product, Curated. Leverage your extensive network and expertise to bui...
2 weeks ago
$156K - $247K *
Lead the charge in patient engagement strategy, optimizing support programs and enhancing the patient journey from consideration to conversion. Collaborate across teams to amplify patient voices and d...
2 weeks ago
Associate Corporate Counsel- Employment and Labor
$87K - $120K *
Champion our legal team by providing expert guidance on employment and labor matters, ensuring compliance and risk management across diverse jurisdictions while collaborating with HR and business lead...
2 weeks ago
$125K - $147K *
Join a team that's redefining revenue operations by enhancing visibility and accountability across the customer journey. Collaborate with marketing and sales to build insightful reporting and drive da...
2 weeks ago
$120K - $145K *
Lead the charge in driving strategic sales initiatives, managing key accounts, and fostering long-term partnerships. Collaborate with cross-functional teams to identify growth opportunities and delive...
2 weeks ago
$85K *
Manage the end-to-end polling process by designing effective surveys, analyzing data, and collaborating with cross-functional teams to deliver strategic insights that inform client decisions and enhan...
Reposted 2 weeks ago
$120K - $175K *
Unlock potential by leading AI deployments that transform customer experiences. Collaborate with cross-functional teams to ensure projects deliver real business outcomes. Take charge of planning, exec...
Reposted 2 weeks ago
Director of Organic Growth - SEO | AEO (Remote)
$125K - $150K *
Shape the future of organic growth by driving strategic digital transformation across channels, improving patient access to mental healthcare through innovative marketing strategies, data-driven insig...
Reposted 2 weeks ago
Maintenance And Engineering Manager
$95K - $115K *
Transform maintenance and reliability performance in a dynamic manufacturing environment. Lead a high-performing team to enhance equipment availability, reduce downtime, and foster a culture of contin...
2 weeks ago
Director, Talent - Talent Management
$110K - $120K *
Elevate talent management by executing core programs, enhancing employee experience, and driving performance initiatives. Lead cross-functional projects, ensuring accountability and operational contin...
2 weeks ago
$135K - $155K *
Drive innovation as you develop and deploy cutting-edge AI solutions that enhance advertising measurement products, collaborating with cross-functional teams to maximize ROI and shape technology at sc...
2 weeks ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.