Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,961
Regional Sales Director (Tampa)
$112K - $143K *
Champion new business growth by building strategic partnerships and expanding market share within your territory. Drive revenue through effective relationship management and a proactive sales strategy...
2 weeks ago
Senior Managing Counsel - Corporate Payments
$170K - $213K *
Manage and lead a team of legal professionals supporting complex commercial transactions and product development in Corporate Payments, ensuring compliance and risk management while fostering collabor...
2 weeks ago
Manager, Nursing, Emergency Department, United Memorial Medical Center
$95K - $140K *
Empower a team dedicated to excellence in clinical practice and patient care. Lead operational, budgetary, and personnel activities while fostering collaboration and quality initiatives to enhance pat...
2 weeks ago
Design Engineer II, High Voltage (Remote)
$90K - $113K *
Shape the future of renewable energy by leading preliminary substation design for utility-scale solar and BESS projects. Collaborate with cross-functional teams to ensure technical excellence from con...
2 weeks ago
Territory Sales Manager, UT/NV
$97K - $151K *
Join us to drive agency growth across Utah and Nevada, enhancing relationships and performance. You'll oversee strategic initiatives, deliver training, and ensure compliance while managing a diverse t...
2 weeks ago
Commercial Physical Damage Field Adjuster
$75K - $129K *
Empower clients by expertly assessing commercial damage claims, negotiating settlements, and delivering exceptional service in diverse environments. Join a dynamic team dedicated to providing top-notc...
2 weeks ago
Field Service Engineer 2 - Kansas City Metro OR Central Iowa
$74K - $112K *
Support customer success by providing expert technical assistance, troubleshooting, and maintenance for hardware systems. Collaborate with sales and service teams to enhance customer satisfaction and...
2 weeks ago
Sr. Regulatory Affairs Specialist - Recall and Post-Market Compliance (Hybird/Remote)
$90K - $135K *
Unlock potential by leading regulatory compliance for IVD products, ensuring adherence to global standards. Collaborate with cross-functional teams to assess risks, manage adverse events, and drive co...
2 weeks ago
Full-stack Engineer 5 - Shopping (Remote-Eligible)
$209K - $238K *
Accelerate transformative tech solutions by leading diverse teams in building innovative cloud-based systems. Collaborate cross-functionally to optimize performance and enhance user experiences, empow...
Reposted 2 weeks ago
$108K - $166K *
Lead corporate audit activities, ensuring compliance and operational excellence across North American entities. Collaborate with stakeholders to assess risks, develop audit plans, and mentor audit sta...
2 weeks ago
Manager, Application Domain Architecture
$124K - $189K *
Join a team that's shaping the future of application architecture by leading strategic initiatives, ensuring alignment with enterprise standards, and driving innovation across technology domains to su...
2 weeks ago
$91K - $163K *
Lead the charge in safeguarding our organization against evolving cyber threats. As a Senior Cybersecurity Engineer, you'll design robust defenses and collaborate across teams to enhance security post...
2 weeks ago
$80K - $95K *
Help us advance high-quality digital design by coordinating BIM workflows across multidisciplinary projects. Leverage your expertise in Revit and Autodesk technologies to ensure model integrity, suppo...
2 weeks ago
Assistant Controller (Director)
$125K - $150K *
Join a dynamic team as you lead corporate accounting operations, driving financial reporting, audits, and process improvements. Shape the future of accounting through strategic leadership and innovati...
2 weeks ago
Director, HR Business Partner - Product and Engineering
$150K - $215K *
Collaborate with senior leaders to design and implement global HR strategies, driving organizational performance and employee engagement while leading a team of HR professionals in a dynamic environme...
2 weeks ago
Principal Subcontract Administrator
$112K - $196K *
Lead subcontract administration efforts, ensuring compliance and effective negotiation while fostering relationships with suppliers and stakeholders. Drive strategic procurement initiatives within the...
2 weeks ago
Sr. Subcontract Administrator (Remote)
$88K - $154K *
Join a team that's dedicated to excellence in subcontract management. Leverage your expertise in procurement to ensure compliance and foster collaboration, driving successful outcomes in our dynamic d...
2 weeks ago
Vice President Contracts, Engineered Systems
$200K - $383K *
Join us to lead the contracts function in a dynamic Federal contracting environment. Oversee a team of 20+ professionals, develop strategies, and negotiate complex contracts while fostering strong rel...
2 weeks ago
$69K - $125K *
Transform regulatory insights into actionable strategies by analyzing national and state legislative activities. Collaborate with legal and business teams to ensure compliance and support effective de...
2 weeks ago
Occupational Therapist - Full-time
$62K - $112K *
Empower patients on their recovery journey by delivering compassionate occupational therapy. Collaborate with healthcare teams to create tailored treatment plans and supervise support staff, ensuring...
2 weeks ago
Senior Technical Product Manager, IT Service Management
$143K - $169K *
Lead the transition to a modern, AI-native ITSM platform, enhancing service management across teams. Drive employee-centric design, streamline workflows, and ensure seamless integration while maintain...
Reposted 2 weeks ago
Field Reimbursement Manager-Southeast
$185K - $230K *
Unlock potential by leading reimbursement strategies for rare disease therapies, integrating provider education with patient support. Collaborate cross-functionally to enhance access and navigate comp...
2 weeks ago
Senior CRM Consultant - HubSpot & Creatio
$88K - $118K *
Join us to transform client CRM strategies by leveraging your HubSpot expertise. Collaborate with teams to design and implement scalable solutions, guiding clients through every stage of their CRM jou...
2 weeks ago
$95K - $115K *
Transform the go-to-market strategy by owning and optimizing HubSpot systems, ensuring seamless integration across Marketing, Sales, and Customer Success to drive measurable business impact and enhanc...
2 weeks ago
$100K - $120K *
Take ownership of data center operations, driving governance and service quality across hybrid environments and ensuring optimal performance and compliance...
Reposted 2 weeks ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.