Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,961
Senior Manager Medical Economics - QuickBase Developer
$82K - $182K *
Develop and maintain QuickBase applications while leading complex analytics projects. Ensure data integrity and support clinical performance reporting. Collaborate with stakeholders to drive continuou...
2 weeks ago
$127K - $172K *
Elevate your career by shaping user experiences as a UI/UX Developer. Leverage 10+ years of expertise in React SPAs and responsive design to modernize financial applications. Collaborate across teams...
Reposted 2 weeks ago
AWS Technical Lead/Sr. Java/Angular Developer
$131K - $178K *
Unlock your potential by leading a dynamic Agile team in developing enterprise applications. Leverage your AWS expertise and hands-on coding skills to drive innovation and mentor developers while ensu...
2 weeks ago
Oracle Application Systems Analyst (Mid-Level)
$83K - $112K *
Transform your career by leveraging your analytical skills to enhance application systems. Collaborate with teams to improve workflows, execute tests, and support mission-driven initiatives that stren...
2 weeks ago
Oracle eBusiness Suite (EBS) Database Administrator
$129K - $175K *
Champion the optimization of mission-critical Oracle EBS environments, ensuring seamless database administration and support for complex financial systems. Collaborate with cross-functional teams to e...
2 weeks ago
Child Support Systems APD/Budget Review Specialist
$93K - $126K *
Join us to support state child support systems modernization initiatives, ensuring compliance with federal requirements and enhancing operational efficiency through effective project management and an...
2 weeks ago
Business Process Analyst Senior
$85K - $115K *
Lead the design and deployment of Power BI solutions, collaborating with cross-functional teams to gather requirements, analyze data, and enhance operational efficiency in secure environments. Drive i...
2 weeks ago
APP (NP/PA) Primary Care Inbox Management (remote)
$119K - $134K *
Partner with us to enhance patient care by supporting primary care teams remotely. Collaborate with on-site providers to manage patient needs effectively, ensuring seamless communication and coordinat...
2 weeks ago
$90K - $100K *
Unlock potential by delivering innovative robotic solutions, ensuring seamless integration and operational success for customers. Collaborate, troubleshoot, and enhance system performance while provid...
2 weeks ago
Senior Advisor, Clinical Pharmacology
$153K - $268K *
Join our team to provide expert clinical pharmacology insights, driving dose selection and study design for innovative therapies. Collaborate with cross-functional teams to translate complex data into...
2 weeks ago
Environmental Compliance Specialist
$70K - $95K *
Join a dedicated team ensuring compliance with environmental regulations. This role involves monitoring operations, conducting audits, and collaborating with agencies to enhance environmental performa...
Reposted 2 weeks ago
Account Specialist (Norfolk, VA)
$160K - $192K *
Grow your career by engaging healthcare providers and driving commercial success. Collaborate with cross-functional teams to support product launches and enhance patient access to innovative therapies...
2 weeks ago
Account Specialists (Peoria, IL)
$160K - $192K *
Join a team that's pivotal in driving commercial performance and product adoption. Engage healthcare providers, build relationships, and support innovative therapies while collaborating with cross-fun...
2 weeks ago
Account Specialist, Olympia, WA
$160K - $192K *
Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative...
2 weeks ago
Account Specialist (Wilkes Barre, PA)
$160K - $192K *
Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and enhance patient access to innovativ...
2 weeks ago
Manager, Strategic Partnerships
$117K - $187K *
Join a team that's dedicated to optimizing strategic partnerships and enhancing service excellence. Lead a skilled team to manage vendor relationships, drive process improvements, and ensure top-tier...
Reposted 2 weeks ago
Clinical Development Medical Director, Early Development - Cardiometabolic
$274K - $371K *
Lead the early phase clinical development of innovative therapeutics, collaborating across teams to design and execute trials. Your expertise will directly influence strategy, protocol development, an...
Reposted 2 weeks ago
$157K - $174K *
Elevate technical execution in GMP manufacturing by leading complex workstreams for comparability strategies, tech transfers, and process improvements. Collaborate with cross-functional teams to ensur...
2 weeks ago
Account Specialist (Madison, WI)
$160K - $192K *
Join a dynamic team to drive commercial performance and enhance patient access through strong relationships with healthcare providers, executing strategic business plans in a pivotal role focused on i...
2 weeks ago
Account Specialist, Des Moines, IA
$160K - $192K *
Optimize commercial performance by engaging healthcare providers and driving product adoption. Collaborate with cross-functional teams to support launches and enhance patient access to innovative ther...
2 weeks ago
Account Specialist (Burlington, MA)
$160K - $192K *
Elevate commercial performance by engaging healthcare providers and driving product adoption. Collaborate with cross-functional teams to support launches and optimize patient access, ensuring complian...
2 weeks ago
Account Specialist (Palo Alto / San Francisco, CA)
$160K - $192K *
Lead the charge in driving commercial performance by engaging healthcare providers, building relationships, and executing territory business plans to ensure patient access to innovative therapies and...
2 weeks ago
Account Specialist (Berlin, DE)
$160K - $192K *
Execute territory business plans to drive commercial performance, engage healthcare providers, and support product launches. Collaborate with cross-functional teams to optimize patient access and ensu...
2 weeks ago
Account Specialist, Lafayette, IN
$160K - $192K *
Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative...
2 weeks ago
$110K - $172K *
Transform project execution by managing integrated schedules for capital projects, ensuring strategic alignment throughout their lifecycle. Collaborate with cross-functional teams to drive results and...
Reposted 2 weeks ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.