Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $110,961

Sort By: Relevance

$120K - $145K *

Champion innovative product development in power connectors and cable assemblies. Lead cross-functional teams, drive technical excellence, and mentor engineering talent to deliver high-quality, cost-e...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$69K - $93K *

Champion innovative IoT solutions by engaging with customers to understand their needs, providing technical expertise, and ensuring seamless integration of our technology into their operations, drivin...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Lead the charge in driving partner-sourced revenue growth and market expansion through strategic alliances in Data, AI, and Cloud. Collaborate with top technology partners to convert relationships int...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$180K - $220K *

Lead the charge in driving growth for our Guidewire InsuranceNow practice by developing strategic relationships, generating new business opportunities, and executing revenue strategies across the US i...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$180K - $220K *

Lead the charge in driving growth across insurance platforms by building strategic alliances, developing executive relationships, and executing market strategies to enhance revenue and expand opportun...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$166K - $192K *

Elevate user experience by leading end-to-end product design, driving stakeholder alignment, and optimizing complex workflows. Utilize your expertise to deliver impactful, user-centered solutions in a...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$174K - $209K *

Innovate within a dynamic team to design and enhance full-stack applications that drive Grafana's core business operations, ensuring seamless customer experiences and robust internal processes across...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$65K - $100K *

Join us in leading and developing high-performing teams while driving exceptional customer service and financial performance. Collaborate across all levels to implement business solutions and foster a...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$65K - $100K *

Explore a dynamic role driving sales and enhancing customer experiences through effective merchandise presentation, team leadership, and loss prevention strategies while fostering a culture of safety...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$184K - $356K *

Transform data processing architectures by optimizing performance and efficiency. Collaborate with diverse teams to enhance user experiences and drive innovation in hardware-software co-design for cut...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Engage in a dynamic role overseeing large projects and teams, ensuring successful delivery through effective stakeholder coordination and project management. Contribute to innovative power delivery so...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$65K - $98K *

Join a team that's committed to excellence by leading and developing associates, ensuring productivity and safety, and fostering a culture of belonging while delivering exceptional results in logistic...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$120K - $150K *

Transform your career by leading a dynamic team to ensure clinical excellence across multiple regions, driving project success through strategic management and collaboration while fostering a culture...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$106K - $284K *

Reimagine application development by leading architecture and scaling core systems. Drive AI integration, mentor teams, and ensure operational excellence across full-stack technologies while deliverin...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$71K - $100K *

Drive strategic initiatives by analyzing market trends and performance metrics. Collaborate with cross-functional teams to develop business cases and forecasts, ensuring data integrity and delivering...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$65K - $98K *

Shape the future by leading a dynamic team, driving productivity, and ensuring quality standards. Collaborate with associates to foster a culture of belonging while delivering exceptional results and...

2 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$135K - $160K *

Transform the Private Equity landscape by leading FP&A initiatives, enhancing operational efficiencies, and mentoring teams to deliver tailored solutions that drive sustainable value creation for clie...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$175K - $210K *

Innovate in AI research by driving cutting-edge projects in cybersecurity. Leverage your expertise in LLMs and model evaluation to translate complex challenges into actionable insights, collaborating...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$65K - $100K *

Drive team success by leading, mentoring, and enhancing customer service while managing financial performance and operational excellence in a dynamic retail environment. Foster a culture of continuous...

2 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$150K - $180K *

Engage with key Insurance clients to drive strategic growth and account management. Leverage your expertise in business development and executive relationships to expand enterprise accounts across the...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Shape the future of governance by building and managing comprehensive GRC frameworks, ensuring regulatory compliance, policy library development, and strategic vendor risk management, while collaborat...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$56K - $109K *

Empower our team by quantifying core laboratory studies and ensuring compliance with industry standards. Collaborate with multidisciplinary teams to enhance echocardiography analysis and contribute to...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$106K - $284K *

Shape enterprise-grade Workforce Management solutions through expert forecasting, staffing, and scheduling. Collaborate with stakeholders to design, deliver, and execute strategies that enhance operat...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $235K *

Lead the charge in developing robust backend applications, driving complex projects from design to launch. Collaborate across teams, mentor junior engineers, and tackle architectural challenges to enh...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $205K *

Join a team that's driving M&A success by leading financial strategy, target evaluation, and integration planning. Collaborate with senior leaders to identify opportunities and execute critical phases...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.