Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,967
$79K - $127K *
Innovate with us to enhance data protection strategies, ensuring robust security and compliance across diverse platforms. Collaborate on complex projects, troubleshoot incidents, and drive improvement...
1 week ago
Director of Safeguarding and Risk
$130K *
Lead the charge in safeguarding and risk management for behavioral health services, ensuring compliance with regulatory frameworks while driving user satisfaction and engagement through strategic coll...
1 week ago
$90K - $110K *
Join a team that's driving growth by generating new B2B opportunities, building industry relationships, and managing the full sales cycle in the modular construction sector. Your expertise will empowe...
1 week ago
$110K - $130K *
Champion business growth by driving market development in healthcare. Build relationships, achieve sales objectives, and influence cross-functional teams to deliver customer-centric solutions while ma...
1 week ago
Senior Space Data and CAD Manager
$115K - $160K *
Join a team that's redefining spatial data management by leading CAD systems and workplace data operations. Drive data quality and governance across portfolios, ensuring actionable insights for stakeh...
1 week ago
Director, Market Access Payer Accounts - Northeast
$197K - $246K *
Lead strategic initiatives in market access by managing key payer accounts, ensuring optimal coverage and reimbursement for products. Collaborate with cross-functional teams to enhance patient access...
1 week ago
$95K - $115K *
Join a team that's driving technical sales excellence in the East Coast market. As a key player, you'll lead the sales cycle, engage with customers, and deliver tailored solutions that drive significa...
1 week ago
Lead, Open Source Program Office
$116K - $194K *
Lead the charge in establishing and advancing the enterprise Open Source Program Office strategy, ensuring effective governance and management of open-source software across the development lifecycle...
1 week ago
Senior Oncology Account Manager, Columbia
$150K - $230K *
Engage with key stakeholders to promote oncology products, build relationships, and drive brand value. Utilize market insights to develop strategic plans, ensuring patient access and compliance while...
1 week ago
Senior Oncology Account Manager, San Jose
$150K - $230K *
Engage with key stakeholders to promote oncology products, build relationships, and drive brand value. Utilize market insights to develop strategic plans, ensuring patient access and exceeding perform...
1 week ago
Senior Oncology Account Manager, Minneapolis
$150K - $230K *
Champion innovative oncology solutions by building strong relationships with key stakeholders. Drive product success through strategic engagement and effective territory management, ensuring timely ac...
1 week ago
Senior Oncology Account Manager, Richmond
$150K - $230K *
Explore opportunities to drive oncology product success by building strong relationships with healthcare professionals, managing territory resources, and delivering impactful solutions that enhance pa...
1 week ago
Senior Analyst, Decision Science (Client Marketing)
$105K - $129K *
Elevate client engagement through data-driven insights! As a Senior Analyst, you'll analyze performance metrics, enhance marketing strategies, and drive client retention, ensuring impactful decisions...
1 week ago
$110K - $130K *
Drive go-to-market strategy for AI-powered healthcare solutions, collaborating cross-functionally to enhance product positioning, messaging, and performance. Own marketing execution and leverage insig...
1 week ago
Principal Pricing and Monetization Manager
$141K - $208K *
Champion innovative pricing strategies that drive revenue growth and enhance customer experience. Lead cross-functional teams to operationalize complex monetization projects, leveraging data analysis...
1 week ago
Full Stack Engineer - Trust and Safety
$187K - $227K *
Engineer robust systems to combat abuse in user interactions, enhance notification reliability, and collaborate across teams to ensure safety and compliance. Drive impactful solutions while maintainin...
1 week ago
Vice President, Client Services
$160K - $200K *
Lead the charge in strategic client services management, overseeing growth, engagement, and high-value account portfolio. Drive team performance and build enduring client relationships that enhance bu...
Reposted 1 week ago
$136K - $187K *
Champion the design and execution of comprehensive benefits programs, ensuring competitive, compliant offerings for a diverse workforce. Collaborate with cross-functional teams to optimize employee ex...
1 week ago
Senior Developer Marketing Manager, Social & Content
$133K - $186K *
Elevate your career by driving developer engagement and community growth through impactful content and strategic partnerships. Collaborate with engineers to enhance product visibility and foster meani...
1 week ago
People Technology Senior Specialist - Reporting & Analytics
$120K - $140K *
Shape the future of HR analytics by designing and maintaining enterprise-level reporting solutions, enabling data-driven decision-making, and partnering with leadership to drive strategic workforce in...
1 week ago
Contractor - Mechanical Engineer 4 (NSSS Vessels & Structures)
$110K - $130K *
Join a team that's engineering advanced nuclear components to meet industry standards. You'll perform design and stress analyses, ensuring compliance with ASME codes while mentoring junior engineers a...
1 week ago
Senior Backend Engineer, External
$199K - $235K *
Innovate backend solutions by designing, building, and maintaining scalable services for external pentesting. Collaborate across teams to enhance user experience and ensure system performance, reliabi...
1 week ago
Principal Engineer, Monetization Engineering
$223K - $317K *
Drive the evolution of a robust Fulfillment platform, shaping architecture and strategy while mentoring teams. Lead modernization efforts to enhance scalability, reliability, and performance, ensuring...
1 week ago
Lead Audit Services Consultant
$100K - $120K *
Oversee consulting engagements to assess risks in processes and controls. Act as a subject matter expert in financial, operational, and IT audits, providing advisory services and enhancing audit funct...
1 week ago
Lead Healthcare Services Software Engineer
$110K - $130K *
Unlock innovation by designing, developing, and maintaining software systems. Collaborate with stakeholders to analyze requirements and ensure solutions meet business needs while providing technical e...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.