Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,967
Senior Software Engineer - Open Source (RD217)
$148K - $201K *
Empower the development of our open source software solutions while collaborating with engineers and community contributors. Leverage your cloud native expertise to enhance mission outcomes through in...
Reposted 1 week ago
$100K - $120K *
Join a team that's committed to transforming literacy by collaborating with school leaders. Leverage your educational leadership experience in a dynamic role, driving partnerships that foster effectiv...
Reposted 1 week ago
Hardware Deployment Project Manager
$100K - $120K *
Champion hardware readiness for customer deployments, ensuring timely delivery and accurate documentation. Collaborate with cross-functional teams to manage escalations, RMAs, and configuration contro...
1 week ago
$135K - $160K *
Champion the delivery of innovative data solutions, leading cross-functional teams to modernize platforms and drive AI integration. Ensure project success through effective management of scope, qualit...
1 week ago
Lead Proposal Developer - Water & Environment
$93K - $126K *
Help us lead complex proposals and interviews, enhancing our proposal practices while mentoring colleagues and driving strategic improvements across the organization. Your expertise will shape our app...
1 week ago
Associate Director, Field Medical Affairs Cutaneous Oncology (Pacific Northwest)
$176K - $287K *
Shape the future of oncology by cultivating relationships with KOLs, providing critical insights, and supporting research initiatives. Drive awareness and education while ensuring compliance and integ...
1 week ago
Senior Manager, Commercial Training (Rare Disease)
$134K - $219K *
Join a team that's dedicated to enhancing commercial training for rare diseases. Lead innovative learning experiences, collaborate with cross-functional teams, and drive impactful training programs th...
1 week ago
$65K - $109K *
Partner with us to foster strategic relationships, optimize account performance, and drive engagement with key stakeholders, leveraging your knowledge of healthcare technology to deliver impactful sol...
Reposted 1 week ago
Senior Oncology Account Manager, Louisville
$150K - $230K *
Elevate patient care by driving oncology product success through strategic relationships and innovative solutions. Collaborate with key stakeholders to ensure timely access to therapies while exceedin...
1 week ago
Senior Oncology Account Manager, Houston
$150K - $230K *
Manage strategic oncology product promotion and build relationships with key stakeholders. Drive performance goals, analyze market data, and ensure patient access to therapies while embodying corporat...
1 week ago
Senior Oncology Account Manager, Indianapolis
$150K - $230K *
Drive impactful oncology solutions by building relationships with key stakeholders. Leverage your expertise to promote innovative products, exceed performance goals, and enhance patient access while n...
1 week ago
Senior Oncology Account Manager, Atlanta North
$150K - $230K *
Unlock potential by driving oncology product success through strategic relationships and innovative solutions. Lead market engagement, exceed performance goals, and ensure patient access while embodyi...
1 week ago
Senior Oncology Account Manager, Albany
$150K - $230K *
Shape the future of oncology by driving product success and building strong relationships with healthcare professionals. Lead initiatives that enhance patient access and deliver innovative solutions i...
1 week ago
Senior Oncology Account Manager, Phoenix West
$150K - $230K *
Engineer impactful relationships in oncology by promoting innovative therapies, driving patient access, and exceeding performance goals. Collaborate with stakeholders to enhance care delivery and leve...
1 week ago
Senior Oncology Account Manager, Detroit
$150K - $230K *
Transform the oncology landscape by driving product success and building strong relationships with key stakeholders. Leverage your expertise to enhance patient access and deliver innovative solutions...
1 week ago
Senior Oncology Account Manager, Los Angeles North
$150K - $230K *
Lead the charge in oncology sales by building strong relationships with key stakeholders, driving product adoption, and ensuring patient access to innovative therapies. Collaborate with internal teams...
1 week ago
Mid-Market Account Executive - MOLAT
$80K - $95K *
Drive new business growth by owning the full sales cycle in the mid-market segment. Leverage your expertise in cybersecurity solutions to maximize revenue and collaborate cross-functionally to achieve...
Reposted 1 week ago
Customer Development Specialist - Florida Gulf
$68K - $93K *
Grow your career with a dynamic team focused on driving sales and enhancing customer relationships in the animal health sector. Utilize innovative strategies and digital tools to maximize performance...
1 week ago
$210K - $250K *
Empower oncology research by leveraging real-world evidence and clinical expertise. Collaborate with cross-functional teams to develop innovative solutions that enhance cancer treatment and support bi...
1 week ago
Field Medical Excellence & Operations
$210K - $255K *
Shape the future of cancer treatment by leading Field Medical Excellence initiatives. Drive operational improvements, strategic planning, and cross-functional collaboration to enhance the impact of ou...
1 week ago
Computer Systems Engineer/ Architect
$110K - $130K *
Unlock potential by designing and optimizing enterprise data solutions in a Databricks Lakehouse environment, supporting critical missions with a focus on scalability and best practices...
Reposted 1 week ago
Technical Delivery Manager - Healthcare, Release Management & AI
$120K - $145K *
Shape the future of patient services by ensuring timely delivery of features and integrations. Collaborate across teams to enhance operational efficiency in a compliance-heavy environment, driving inn...
1 week ago
Manager, Tagging and Analytics
$113K - $130K *
Join a team that's dedicated to ensuring data quality and governance in retail analytics. You'll lead tagging initiatives, collaborate with internal and external partners, and empower teams with best...
1 week ago
Senior Digital Marketing Specialist
$80K - $95K *
Unlock potential by driving growth marketing strategies that enhance visibility and engagement with federal agencies. Collaborate with business development to create impactful campaigns and manage eve...
1 week ago
Backend Software Engineer, SDK
$145K - $200K *
Transform your career by developing robust SDKs that empower customers globally. Collaborate with cross-functional teams to enhance performance and resiliency while contributing to open-source project...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.