Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,967
Area Sales Director, Southwest
$415K - $435K *
Empower your career by leading regional Enterprise sales strategies to drive business growth and expand market presence. Manage high-performing teams and build relationships with C-suite executives to...
Reposted 1 week ago
Quality Control Specialist, Medical Writing
$74K - $99K *
Shape the future of regulatory submissions by ensuring high-quality QC reviews of clinical documents. Collaborate with global teams to meet project timelines while maintaining compliance with industry...
Reposted 1 week ago
Senior Cybersecurity Disaster Recovery & Contingency Planning SME
$140K - $150K *
Lead the charge in nationwide Cybersecurity Disaster Recovery and Contingency Planning initiatives, providing strategic oversight and technical expertise to enhance organizational resilience and ensur...
1 week ago
Associate General Counsel, Corporate
$178K - $225K *
Lead legal support for Finance and Capital Markets, ensuring compliance and strategic execution of ABS transactions and SEC reporting, while managing counsel and navigating complex agreements to drive...
Reposted 1 week ago
$100K - $150K *
Lead the charge in enhancing infrastructure reliability and automation for large-scale game development projects, collaborating with teams to implement cloud solutions and streamline CI/CD processes...
1 week ago
Regional Vice President, Public Sector
$253K - $398K *
Shape the future of public sector sales by driving growth and building relationships with key stakeholders. Leverage your expertise to uncover opportunities and deliver impactful digital solutions tha...
1 week ago
Lead Forward Deployed Engineer (AI Enablement)
$194K - $272K *
Elevate AI solutions by leading engineering efforts that transform business workflows. Collaborate with teams to identify opportunities, prototype solutions, and implement scalable AI applications tha...
1 week ago
Senior Full-Stack Software Engineer
$120K - $145K *
Champion the development of impactful software solutions, collaborating across teams to enhance educational tools. Take ownership of code quality and performance, while mentoring peers and leveraging...
1 week ago
$130K - $155K *
Join a team that's redefining data infrastructure by owning and optimizing our data pipelines, warehouse, and modeling layers. Collaborate with cross-functional teams to ensure data integrity and driv...
Reposted 1 week ago
Senior Oncology Account Manager, Baltimore
$150K - $230K *
Lead the promotion of oncology products, building strong relationships with key stakeholders. Drive performance goals, manage territory effectively, and ensure patient access to treatments while embod...
1 week ago
Senior Oncology Account Manager, Jacksonville
$150K - $230K *
Transform the oncology landscape by driving product success and building strong relationships with healthcare professionals. Leverage your expertise to enhance patient access and deliver innovative so...
1 week ago
Senior Oncology Account Manager, Pittsburgh
$150K - $230K *
Empower oncology practices by driving product adoption and building relationships with key stakeholders. Lead strategic initiatives to enhance patient access and optimize territory management while ex...
1 week ago
Senior Oncology Account Manager, Little Rock
$150K - $230K *
Join us to drive the promotion of innovative oncology products, build strong relationships with healthcare professionals, and exceed performance goals while ensuring patient access to vital treatments...
1 week ago
Senior Oncology Account Manager, Jersey North
$150K - $230K *
Grow your career with a dynamic role that drives oncology product success, builds key relationships, and enhances patient access through strategic engagement and innovative solutions in a competitive...
1 week ago
Marketing Technology Program Manager
$110K - $130K *
Unlock the potential of marketing technology by leading cross-functional programs that enhance campaign performance, streamline processes, and drive innovation through AI and automation. Collaborate w...
1 week ago
Vice President, CMC Regulatory Affairs
$272K - $340K *
Elevate your career by leading CMC Regulatory strategy and execution. Drive submissions, build a high-performing team, and engage with global health authorities to ensure compliance and success in dru...
1 week ago
Lead Director, Provider Service Model Lead
$100K - $231K *
Join our dynamic Network team to lead complex projects, enhance provider experiences, and drive strategic initiatives. Collaborate with cross-functional teams to optimize network infrastructure and en...
1 week ago
Mechanical Engineering Lead, NA
$175K - $190K *
Explore strategic leadership in mechanical engineering, guiding a team of experts to innovate and deliver top-tier data center solutions. Collaborate cross-functionally to shape engineering standards...
1 week ago
Leader, Solutions Engineer, Splunk
$209K - $275K *
Elevate your career by leading and developing a high-performing Solutions Engineering team. Drive strategic alignment across functions, foster technical excellence, and implement innovative practices...
Reposted 1 week ago
Credit Risk Review - Strategic Insight Team Manager
$128K - $268K *
Lead the charge in transforming credit risk management through strategic oversight, multidisciplinary team leadership, and innovative solutions. Drive operational excellence and governance while ensur...
1 week ago
Senior Routing Engine Developer (CX Platform)
$120K - $145K *
Deliver innovative routing solutions for enterprise-scale contact centers. Design and build a robust routing engine that intelligently distributes interactions across various channels, ensuring high a...
1 week ago
Field Service Engineer - New England
$90K - $100K *
Join a team that's dedicated to delivering exceptional field service support for Bioprocess products. In this role, you'll ensure customer satisfaction through installations, repairs, and maintenance...
1 week ago
Principal Technical Product Manager
$138K - $165K *
Elevate your career by leading complex product initiatives across technical domains. Collaborate with cross-functional teams to drive strategic direction into actionable plans, ensuring measurable out...
1 week ago
$130K - $155K *
Join a dynamic team as a key partner in revenue operations, collaborating with sales leadership to drive growth, manage forecasting, and enhance business strategies across multiple units. Embrace inno...
1 week ago
$120K - $150K *
Lead the charge in developing strategic frameworks that translate business objectives into actionable insights. Collaborate cross-functionally to identify growth opportunities and influence decision-m...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.