Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,967
$65K - $108K *
Lead the charge in ensuring coding accuracy and compliance by reviewing medical records and documentation. Utilize ICD-10 and CPT systems to uphold quality standards while responding to coder inquirie...
1 week ago
Senior Product Manager, Marketplace Supply
$120K - $145K *
Accelerate progress at a dynamic marketplace by owning the Driver App, enhancing user experience, and driving engagement. Collaborate cross-functionally to optimize workflows and improve marketplace h...
1 week ago
$110K - $130K *
Drive the design and enhancement of corporate security infrastructure, improving automation and maintaining strong security posture in a cloud environment. Collaborate with teams to implement controls...
Reposted 1 week ago
$100K - $150K *
Drive strategic sales initiatives and expand business within light industrial, hospitality, and retail sectors. Manage full sales process from prospecting to closing while collaborating across teams t...
Reposted 1 week ago
Technical Solutions Architect - Anthropic / Claude Cowork
$165K - $185K *
Lead the charge in transforming organizations through AI adoption. Collaborate with cross-functional teams to design and implement innovative solutions that enhance productivity and drive measurable o...
1 week ago
Workforce AI Business Development Manager
$145K - $160K *
Drive the future of Workforce AI by leading business development initiatives, engaging with executives, and translating complex technology into impactful solutions that enhance enterprise productivity...
1 week ago
Technical Product Manager - AI & Data Analytics
$155K - $160K *
Drive the data and AI strategy by collaborating with clients, shaping predictive roadmaps, and translating complex problems into actionable product development, enhancing customer-facing analytics and...
Reposted 1 week ago
Physician - Diagnostic Tele-Radiologist
$210K - $250K *
Grow your career by providing comprehensive diagnostic radiology services, including consultations and interpretations for a diverse patient population. Collaborate remotely to ensure timely and accur...
1 week ago
Sr. Account Manager - Health Plans
$180K - $205K *
Champion client success by managing strategic accounts, driving growth, and enhancing relationships with health plans. Collaborate cross-functionally to deliver tailored solutions and ensure seamless...
1 week ago
$80K - $120K *
Grow your career with a dynamic team focused on client retention and revenue growth. Drive go-to-market strategies for new products while nurturing key relationships and championing client needs in a...
1 week ago
Pharmacy District Manager, Amazon Pharmacy
$130K - $176K *
Inspire operational excellence as a strategic leader overseeing 8-10 pharmacies. Drive compliance, enhance patient care, and develop talent while ensuring consistent performance across multiple locati...
1 week ago
Remote Endpoint Engineering Senior Systems Architect (VA ESOM)
$145K - $185K *
Lead enterprise-level architectural initiatives to enhance endpoint technologies, guiding modernization efforts and integrating emerging solutions across multiple divisions while ensuring security and...
1 week ago
$150K - $180K *
Champion a transformative product vision, leading cross-functional teams to drive strategic outcomes in a dynamic digital health environment. Shape the future of patient care and client experience whi...
1 week ago
$80K - $95K *
Shape the future of content marketing by owning strategy and execution across channels. Collaborate with teams to create impactful, high-quality content that resonates with audiences and drives engage...
1 week ago
Senior Director, Client Services B2B
$136K - $155K *
Champion integrated B2B marketing strategies by leading client relationships, driving account growth, and connecting marketing performance to business outcomes. Collaborate with cross-functional teams...
1 week ago
Technical Product Manager (Integrated Solutions)
$180K - $220K *
Lead the integration of complex defense solutions by translating tactical requirements into innovative products. Collaborate with cross-functional teams to optimize performance and drive market adopti...
1 week ago
Technical Product Manager (Spectrum Dominance)
$180K - $220K *
Innovate your career by joining a dynamic team focused on translating complex defense requirements into actionable software features, driving product adoption and revenue growth in the Spectrum Domina...
1 week ago
Software Customer Service Manager
$100K - $115K *
Join a team that's dedicated to enhancing customer success through expert management of software solutions, ensuring exceptional service delivery and operational excellence in public safety environmen...
1 week ago
Product Quality Leader - Home Energy
$83K - $105K *
Join a dynamic team to lead product quality initiatives, ensuring excellence from supplier to customer. Drive continuous improvement and defect prevention while fostering a culture of quality and acco...
1 week ago
$120K - $180K *
Drive the growth of our partner channel by leading recruitment and strategy for ISVs, VARs, and ISOs in the payments landscape. Collaborate across teams to enhance partner relationships and expand rev...
1 week ago
$150K - $165K *
Transform your career by leading technical direction and architecture for complex systems. Collaborate across teams to drive innovation, establish standards, and mentor engineers while ensuring alignm...
1 week ago
$95K - $106K *
Optimize legal operations by providing expert advice on contracts, collaborating with teams, and ensuring compliance. Leverage your transactional law experience to streamline processes and support the...
1 week ago
Director, Applied Behavior Research
$105K - $136K *
Shape the future of animal welfare by leading innovative research projects focused on companion animal behavior and welfare. Collaborate across teams to translate findings into impactful applications...
1 week ago
$150K - $180K *
Join a team that's shaping the future of platform engineering, driving innovation across cloud, DevOps, and site reliability. This role empowers you to build core services, enhance architecture, and m...
Reposted 1 week ago
$145K - $157K *
Transform space operations by leveraging Kubernetes to deliver resilient solutions. Collaborate within an Agile framework to enhance software deployment, ensuring optimal performance and security for...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.