Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,967
$110K - $130K *
Lead growth marketing initiatives to scale acquisition channels, optimize conversion, and enhance measurement. Collaborate with freelance specialists to build a sustainable pipeline and drive impactfu...
1 week ago
Regional Sales Director, Territory Sales
$240K - $280K *
Drive sales excellence by leading a high-performing team, executing strategic territory plans, and fostering consultative relationships with key customers to enhance revenue and market share...
1 week ago
$110K - $130K *
Engage in driving revenue growth by targeting key enterprise accounts, leveraging your expertise in digital transformation and customer experience to foster relationships and secure large contracts in...
1 week ago
$80K - $100K *
Drive financial crime detection and investigation by monitoring customer activity, managing alerts, and documenting findings. Collaborate with a growing team to shape processes and standards in a dyna...
1 week ago
$147K - $250K *
Empower a dynamic sales team to drive growth in regional and community banks. Lead strategic initiatives, foster client relationships, and deliver innovative fintech solutions while achieving sales ex...
1 week ago
Litigation Attorney Workers' Compensation (California)
$119K - $201K *
Empower your legal career by managing complex workers' compensation cases, providing strategic litigation services, and delivering expert legal advice to ensure optimal outcomes for clients and claims...
1 week ago
$90K - $110K *
Unlock potential by enhancing revenue operations through data-driven workflows, improving systems, and automating processes. Collaborate with cross-functional teams to ensure efficiency and scalabilit...
1 week ago
Sr. Project Manager, Construction (Remote)
$120K - $130K *
Manage construction projects for new builds and remodels, overseeing vendors and maintaining quality standards while ensuring timely delivery and adherence to budgets. Foster collaboration with stakeh...
Reposted 1 week ago
Manager of Revenue Cycle & Compliance
$120K - $135K *
Transform compliance oversight in the DME order-to-payment lifecycle. Lead audits, analyze data, and coordinate payer audits while developing practical controls and reporting to enhance revenue integr...
1 week ago
Senior Roadway Transportation Engineer
$120K - $150K *
Transform communities by leading roadway design projects, ensuring timely execution and budget management while collaborating with clients and teams to deliver impactful transportation solutions...
1 week ago
Senior Project Engineer - Multidisciplinary
$125K - $150K *
Drive impactful engineering solutions by leading a multidisciplinary team in delivering innovative projects across water and transportation sectors, ensuring quality and efficiency within budget and t...
1 week ago
Senior Manager, Accounting & Finance
$165K - $190K *
Lead the charge in shaping financial strategy and operations, overseeing accounting, financial planning, and analysis. Drive integration across revenue models while managing a skilled finance team to...
1 week ago
$86K - $144K *
Unlock potential by leading the design and development of scalable generative AI services, ensuring architectural integrity and mentoring teams. Collaborate with cross-functional stakeholders to drive...
Reposted 1 week ago
Sales Enablement Support Manager
$80K - $107K *
Join us to develop and manage educational resources that enhance Commercial readiness across clinical data solutions. Collaborate with cross-functional teams to translate complex information into acti...
1 week ago
$100K - $120K *
Elevate customer relationships by managing and growing strategic national accounts. Focus on retention, upselling, and cross-selling within the Collision and Mechanical sectors while leveraging SaaS s...
1 week ago
$143K - $183K *
Shape the future of security testing by identifying vulnerabilities in AI-driven systems. Collaborate with engineers to enhance security protocols and tools, ensuring robust protection for innovative...
1 week ago
Technical Services Engineer - Federal
$125K - $150K *
Join a team that's dedicated to providing exceptional post-sales technical support for federal clients. You'll troubleshoot complex systems, collaborate with engineering teams, and ensure seamless ope...
1 week ago
Clinical Development Director, Early Development Oncology
$274K - $371K *
Develop and lead early phase clinical strategies for oncology candidates, ensuring design and execution of clinical trials. Collaborate with internal teams and external experts to drive innovative dru...
Reposted 1 week ago
$70K - $142K *
Join a team that's dedicated to driving successful product launches and maximizing adoption. This role coordinates cross-functional efforts, ensuring effective communication and readiness across depar...
1 week ago
Senior Software Engineer - Data Infrastructure
$175K - $200K *
Optimize our data infrastructure platform by enhancing automation, observability, and stability. Drive architectural changes to support long-term service requirements while ensuring high throughput an...
1 week ago
$80K - $90K *
Champion the analysis and resolution of complex liability claims, ensuring timely adjudication and client satisfaction. Collaborate with a dedicated team while leveraging industry expertise across mul...
1 week ago
Quality Compliance Senior Manager
$132K - $178K *
Lead a dynamic team to optimize quality oversight through data-driven insights, ensuring compliance and continuous improvement in R&D processes. Drive governance and operational excellence in quality...
1 week ago
Principal Machine Learning Engineer (Memory & Context)
$199K - $334K *
Champion the architecture and engineering of agent memory systems, leading the development of context-driven AI agents. Drive innovation and technical direction while collaborating across teams to enh...
1 week ago
$110K - $130K *
Transform your career by driving market development in quantum technology. Engage with strategic accounts and forge strong relationships while identifying new business opportunities and expanding exis...
Reposted 1 week ago
Manager, Corporate Portfolio and M&A
$138K - $150K *
Elevate your career by managing corporate portfolio growth through strategic projects and business development in a dynamic environment. Collaborate with leadership and cross-functional teams to drive...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.